[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625713":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":25,"responsibleParty":60,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":10,"studyType":81,"phases":10,"briefSummary":82,"conditions":83,"keywords":87,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"German Institute of Human Nutrition","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group A",null,"Night workers",{"label":13,"type":10,"description":14,"interventionNames":10},"Group B","Individuals not working night shifts",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Olga Ramich, Prof. Dr.","CONTACT","+49 33200 882749","olga.ramich@dife.de",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Anna Merckens","+49 33200 882459","anna.merckens@charite.de",[26,45],{"facility":27,"status":28,"city":29,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Charité - Universitätsmedizin Berlin, CharitéCentrum für Anästhesiologie und Intensivmedizin (CC 07) + CIP - Charité Intensivpflege","RECRUITING","Berlin","Germany","DE",{"type":33,"coordinates":34},"Point",[35,36],13.41053,52.52437,{"lat":36,"lon":35},[39,43],{"name":40,"role":18,"phone":41,"phoneExt":10,"email":42},"Enrico Schlunk","+49 30 450 577 048","enrico.schlunk@charite.de",{"name":40,"role":44,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"facility":46,"status":28,"city":29,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":47,"geoPoint":49,"contacts":50},"Charité-Universitaetsmedizin Berlin, Department of Anesthesiology and Intensive Care Medicine (CCM\u002FCVK)",{"type":33,"coordinates":48},[35,36],{"lat":36,"lon":35},[51,55,57],{"name":52,"role":18,"phone":53,"phoneExt":10,"email":54},"Claudia Spies, Univ.-Prof. Dr. med.","+49 30 450 55 11 02","claudia.spies@charite.de",{"name":56,"role":44,"phone":10,"phoneExt":10,"email":10},"Claudia Spies, Prof. Dr.",{"name":58,"role":59,"phone":10,"phoneExt":10,"email":10},"Kathrin Scholtz, Dr. rer. medic.","SUB_INVESTIGATOR",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Olga Ramich (formerly Pivovarova)","Prof., Department Head",[65],{"name":66,"class":6},"Charite University, Berlin, Germany","100625713","impact-of-shift-work-on-glucose-and-lipid-metabolism-of-hospital-workers-100625713",false,"NCT07426211","Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers","METASHIFT","Inclusion Criteria:\n\n* Aged between 18 and 67\n* Male or female\n* Currently employed\n* Body-Mass-Index (BMI) \\\u003C40 kg\u002Fm2\n* Working hours ≥28 hours\u002Fweek\n* Employees working night shifts (group A): (1) Working night shifts for \\>1 year, (2) at least two night shifts within the 2-week observation period\n* Employees not working night shifts (group B): No night shifts for \\>1 year\n* Capable of giving consent\n* Health insurance\n* Good knowledge of German\n\nExclusion Criteria:\n\n* Pregnancy and breastfeeding\n* Special diets, e.g. intermittent fasting\n* Severe acute or chronic diagnosed conditions, e.g., diabetes mellitus, liver or kidney disease (e.g., cirrhosis of the liver or kidney disease with a GFR \\\u003C 60), heart attack within the last 6 months, stroke, or systemic infections; current cancer or cancer diagnosed within the last 2 years\n* Bariatric surgery\n* Hereditary or acquired blood clotting disorders\n* severe mental health conditions, e.g., substance use disorders, eating disorders, or uncontrolled depression (individual assessment by study staff, if necessary following consultation with a physician)\n* Holiday in a different time zone (≥ 2 hours time difference) one month before study participation or within the 2-week observation phase\n* Participation in another study that could influence the results of the current study\n* Specific drug therapies that could influence the study results, e.g., antidiabetic medications including GLP-1 analogs, melatonin (Individual assessment by study staff, if necessary after consultation with a physician)\n* Implanted electronic medical devices, e.g., pacemakers or neurostimulators (to be assessed on a case-by-case basis by study staff, following consultation with a physician if necessary)\n* Physical or mental difficulties in understanding and following instructions from study staff",true,"ALL","18 Years","67 Years",{"count":79,"type":80},48,"ESTIMATED","OBSERVATIONAL","The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff, comparing employees with night shifts to employees without night shifts.",[84,85,86],"Chronodisruption","Shift Work Disorder","Glucose and Lipid Metabolism",[88,89,90,91,92],"Shift work","Circadian clocks","Nutrition","Glucose metabolism","Lipid metabolism","2026-08-10",{"date":95,"type":96},"2026-08-11","ACTUAL",{"date":98,"type":96},"2026-06-01",{"date":100,"type":80},"2028-01",{"name":62,"class":6},2]