[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650479":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":33,"responsibleParty":49,"collaborators":20,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":20,"enrollmentInfo":60,"targetDuration":20,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":75,"whyStopped":20,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Implementation of Virtual reality exposure","EXPERIMENTAL","The investigators designed the VRE protocol based on our two studies: one proof-of-concept study, and a second study measuring VRE efficacy (both manuscripts under review). We found our VRE protocol to be highly feasible, usable, satisfying, and to lead to significant improvements in our outcomes focused on ease of vaginal insertion and associated vaginal pain. Participants will take part in a one-time 120-minute session, in addition to standard clinical care at the BCCVH, and complete study questionnaires before the VRE session and at follow-up time points to evaluate clinical outcomes. The VRE session will adhere to 3 key principles: (i) Exposure is prolonged; patients view a sexual scene multiple times; (ii) Treatment proceeds gradually, with the sexual activities depicted moving from non-penetrative (low fear) to penetrative (high fear); and (iii) Exposures are repeated, with participants re-watching the videos until their fear response has habituated.",[13],"Behavioral: Implementation of Virtual Reality Exposure",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Implementation of Virtual Reality Exposure","To inform implementation, clinicians at BCCVH (n=6) will participate in individual semi-structured interviews prior to implementation to identify barriers and facilitators. Findings from these interviews will refine the implementation protocol. Following implementation, clinicians will complete questionnaires assessing implementation outcomes, including adoption, implementation, and maintenance.\n\nParticipants (n=167) will receive a single VRE session in addition to standard clinical care at the BCCVH. The VRE session is designed to support treatment of vaginismus and will be delivered according to the study protocol. Participants will complete study questionnaires at baseline and follow-up.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Lori Brotto","The University of British Columbia","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Lauren Selden","CONTACT","604-875-4111","68901","lselden@student.ubc.ca",[34],{"facility":35,"status":20,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Gordon and Leslie Diamond Health Care Centre","Vancouver","British Columbia","V5Z 1M9","Canada","CA",{"type":42,"coordinates":43},"Point",[44,45],-123.11934,49.24966,{"lat":45,"lon":44},[48],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},{"type":25,"investigatorFullName":23,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Professor and Licensed Psychologist","100650479","implementing-virtual-reality-exposure-therapy-for-vaginismus-from-efficacy-to-clinical-integration-vivid-3-100650479",false,"NCT07747298","Implementing Virtual Reality Exposure Therapy for Vaginismus: From Efficacy to Clinical Integration (VIVID 3)","VIVID 3","Inclusion Criteria:\n\n* Diagnosis of vaginismus defined by a \"marked fear or anxiety about vulvovaginal or pelvic pain in anticipation of, during, or because of vaginal penetration\" (criterion from the DSM-5 definition of Genito-Pelvic Pain Penetration Disorder)\n* Aged \\>19 y, of any sexual orientation\n* Fluent in English (psychoeducational materials and questionnaires delivered in English)\n* Normal or corrected-to-normal vision (to view the VR scenes during exposure)\n* Able to travel to Vancouver\n\nExclusion Criteria:\n\n* Presence of: unprovoked vaginal pain\n* Vulvar skin condition (i.e., lichen sclerosus)\n* Epilepsy characterized by photosensitive seizures.\n\nNote: provoked vulvar pain is not an exclusion criterion because at least 40% of people with vaginismus report pain with attempted penetration.","FEMALE","19 Years",{"count":61,"type":62},167,"ESTIMATED","INTERVENTIONAL",[65],"NA","Vaginismus, a condition characterized by involuntary tightening of the pelvic floor muscles due to strong fear of vaginal insertion, impact ≥6% of the female population and can make vaginal intercourse and medical exams difficult. This project explores virtual reality exposure (VRE) as a new treatment approach. Building on our two previous studies showing that VRE is feasible and effective in helping patients to gradually face feared sexual encounters in a virtual environment, we aim to implement our VRE protocol at the BC Centre for Vulvar Health (BCCVH). We will assess barriers\u002Ffacilitators to implementation, clinician uptake, and patients' outcomes and engagement.",[68,69],"Vaginismus","Difficulties With Vaginal Penetration",[71,72,73,74,68],"Virtual reality","Digital health","Sexual health","Implementation science","NOT_YET_RECRUITING","2026-07-30",{"date":78,"type":79},"2026-08-05","ACTUAL",{"date":81,"type":62},"2026-09-01",{"date":83,"type":62},"2028-09-01",{"name":5,"class":6},1]