[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655545":3},{"organization":4,"outcomesModule":7,"designInfo":55,"detailedDescription":54,"studyPopulation":54,"armGroups":61,"interventions":73,"overallOfficials":83,"centralContacts":54,"locations":54,"responsibleParty":87,"collaborators":54,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":54,"eligibilityCriteria":95,"healthyVolunteers":91,"sex":96,"minAge":97,"maxAge":54,"enrollmentInfo":98,"targetDuration":54,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":111,"whyStopped":54,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":54},{"fullName":5,"class":6},"Duke University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":40,"otherOutcomes":54},[9,13,17,21,25,27,31,34,37],{"measure":10,"description":11,"timeFrame":12},"Feasibility, as measured by number of participants recruited","recruitment of 30 patients in 6 months","6 months",{"measure":14,"description":15,"timeFrame":16},"Feasibility, as measured by screening to enrollment ratio","screen to enrollment ratio \\>30%","from screening to enrollment, approximately 2 weeks",{"measure":18,"description":19,"timeFrame":20},"Feasibility, as measured by completion rate of the comprehensive medication review","60% completion of the comprehensive medication review","from enrollment to completion of 6 month follow up",{"measure":22,"description":23,"timeFrame":24},"Feasibility, as measured by completion rate of the adherence log","80% completion of the adherence log at 3 months","3 months",{"measure":22,"description":26,"timeFrame":12},"60% completion of the adherence log at 6 months",{"measure":28,"description":29,"timeFrame":30},"Acceptability, as measured by Acceptability of Intervention Measure","5-point scale ranging from 1 (completely disagree) to 5 (completely agree). Higher scores indicating greater acceptability of the intervention.","3 months, 6 months",{"measure":32,"description":33,"timeFrame":30},"Usability, as measured by the System Usability Score of the Medisafe application","The System Usability Score is a 10-item questionnaire that has been validated for mobile applications. This scales all values from 0 to 4 (with four being the most positive response).",{"measure":35,"description":36,"timeFrame":24},"Patient-centeredness, as measured by the Patient-Centered Care Questionnaire","The Patient-Centered Care Questionnaire assesses the extent to which care delivery aligns with the core principles of patient-centered care and includes dimensions like respect for patient preferences, emotional support, and physical comfort. The response options are scored from 1 to 5, with higher scores representing better outcome.",{"measure":38,"description":39,"timeFrame":24},"Patient-centeredness, as measured by the Patient-Centered Outcomes Questionnaire","The Patient-Centered Outcomes Questionnaire measures whether healthcare interventions address the issues patients consider most important. It emphasizes outcomes that matter most to patients, such as symptom relief, quality of life, and emotional well-being. The response options are scored from 1 to 5, with higher scores representing better outcome.",[41,45,48,51],{"measure":42,"description":43,"timeFrame":44},"Quality of life, as measured by the 20-item Short Form Survey","Uses a 0% to 100% scale where higher scores always indicate better health.","Baseline, 3 months, 6 months",{"measure":46,"description":47,"timeFrame":44},"Financial well-being, as measured by the Comprehensive Score for Financial Toxicity","Each question is answered on a 0 to 4 scale. The lower numbers indicate worse (more severe) financial toxicity, while higher numbers indicate better financial well-being.",{"measure":49,"description":50,"timeFrame":44},"Patient activation, as measured by the Patient Activation Measure","Patient Activation Measure evaluates the patient's knowledge, skill, and confidence in managing their health, focusing on how engaged patients are in their care and whether they feel empowered in decision-making processes. Each of the 10 statements is scored form 1 (strongly disagree) to 4 (strongly agree). Higher scores show greater patient empowerment and engagement.",{"measure":52,"description":53,"timeFrame":44},"Adherence, as measured by the Adherence to Refills Medication Scale","Adherence to Refills Medication Scale , a validated survey on barriers to adherence, and logs obtained from the Medisafe mobile application. Uses a 4-point scale, 1 (none of the time) to 4 (all of the time) where lower scores show better adherence and fewer barriers.",null,{"allocation":56,"interventionModel":57,"interventionModelDescription":54,"primaryPurpose":58,"observationalModel":54,"timePerspective":54,"maskingInfo":59},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":60,"maskingDescription":54,"whoMasked":54},"NONE",[62,69],{"label":63,"type":64,"description":65,"interventionNames":66},"Intervention Arm","EXPERIMENTAL","Pharmacist-led medication review plus Medisafe app support.",[67,68],"Behavioral: Medisafe Medication Management Program","Behavioral: Pharmacist-Led Medication Review",{"label":70,"type":71,"description":72,"interventionNames":54},"Control Arm","NO_INTERVENTION","Usual care.",[74,79],{"type":75,"name":76,"description":77,"armGroupLabels":78,"otherNames":54},"BEHAVIORAL","Medisafe Medication Management Program","Training and use of Medisafe application for medication adherence support.",[63],{"type":75,"name":80,"description":81,"armGroupLabels":82,"otherNames":54},"Pharmacist-Led Medication Review","Comprehensive medication review and education by pharmacist.",[63],[84],{"name":85,"affiliation":5,"role":86},"Deborah Kaye","PRINCIPAL_INVESTIGATOR",{"type":88,"investigatorFullName":54,"investigatorTitle":54,"investigatorAffiliation":54,"oldNameTitle":54,"oldOrganization":54},"SPONSOR","100655545","improving-adherence-to-chronic-disease-medication-regimens-among-patients-with-recently-diagnosed-cancer-a-pilot-study-100655545",false,"NCT07811258","Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed Cancer","Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed Cancer: A Pilot Study","Inclusion Criteria:\n\n* diagnosed with breast, colorectal, lung or prostate cancer in the previous 12 months\n* had no prior diagnosis of cancer\n* are currently undergoing chemotherapy or radiation and\u002For underwent surgery in the prior 3 months\n* had \\>2 chronic conditions for \\>1 year prior to cancer diagnosis\n* are prescribed \\>1 non-cancer medication(s)\n\nExclusion Criteria:\n\n* cannot read and communicate in English\n* do not have a smartphone","ALL","18 Years",{"count":99,"type":100},30,"ESTIMATED","INTERVENTIONAL",[103],"NA","This pilot study evaluates a pharmacist-led medication adherence intervention and Medisafe mobile application among patients with newly diagnosed cancer and multimorbidity. Thirty participants will be randomized to intervention or usual care to assess feasibility, acceptability, usability, and preliminary efficacy.",[106],"Cancer",[108,109,110],"Medication Adherence","Cancer Survivorship","Multimorbidity","NOT_YET_RECRUITING","2026-09-28",{"date":114,"type":115},"2026-10-01","ACTUAL",{"date":117,"type":100},"2026-09-07",{"date":119,"type":100},"2027-06-30",{"name":5,"class":6}]