[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648874":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":40,"locations":48,"responsibleParty":65,"collaborators":26,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":26,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":26,"enrollmentInfo":76,"targetDuration":26,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":50,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Lahore University of Management Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment Arm (new GPT-4o Interface)","EXPERIMENTAL","Participants can access any assistance methods they would typically employ (e.g., web search or health portals) in addition to a new LLM interface (based on GPT-4o) to complete medical scenarios. The new LLM interface uses a fixed system prompt that (a) instructs the model to ask targeted clarifying questions before providing any diagnostic or triage suggestions, and (b) requires all final responses to follow a structured template listing: possible conditions, approximate likelihood of each, and a recommended triage with brief reasoning.",[13],"Device: new GPT-4o Interface",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","PLACEBO_COMPARATOR","Participants can use any assistance methods they would typically employ (e.g., web search or health portals) in addition to a standard LLM (GPT-4o) to complete medical scenarios. AI-overview in web searches will be disabled via an extension. They would not be allowed to access any LLMs other than the standard LLM interface.",[19],"Other: Control",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","new GPT-4o Interface","Participants can access any assistance methods they would typically employ (e.g., web search or health portals) in addition to a new LLM (GPT-4o) interface to complete medical scenarios. The new LLM interface uses a fixed system prompt that (a) instructs the model to ask targeted clarifying questions before providing any diagnostic or triage suggestions, and (b) requires all final responses to follow a structured template listing: possible conditions, approximate likelihood of each, and a recommended triage with brief reasoning.",[9],null,{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Participants use any assistance methods they would typically employ at home (e.g., Google or health portals) in addition to a standard LLM (GPT-4o) to complete medical scenarios. AI-overview in web searches will be disabled via an extension. They would not be allowed to access any LLMs other than the standard LLM interface.",[15],[31,35,38],{"name":32,"affiliation":33,"role":34},"Ihsan Ayyub Qazi, PhD","Lahore University of Management Sciences (LUMS)","STUDY_CHAIR",{"name":36,"affiliation":33,"role":37},"Ayesha Ali, PhD","PRINCIPAL_INVESTIGATOR",{"name":39,"affiliation":33,"role":37},"Zafar Ayyub Qazi, PhD",[41,45],{"name":32,"role":42,"phone":43,"phoneExt":26,"email":44},"CONTACT","+923233333766","ihsan.qazi@lums.edu.pk",{"name":36,"role":42,"phone":46,"phoneExt":26,"email":47},"04235608368","ayeshaali@lums.edu.pk",[49],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":57,"coordinates":58},"Point",[59,60],74.35071,31.558,{"lat":60,"lon":59},[63,64],{"name":32,"role":42,"phone":43,"phoneExt":26,"email":44},{"name":36,"role":42,"phone":46,"phoneExt":26,"email":47},{"type":37,"investigatorFullName":32,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Professor","100648874","improving-ai-assisted-medical-diagnosis-and-triage-by-the-general-public-100648874",false,"NCT07728513","Improving AI-Assisted Medical Diagnosis and Triage by the General Public","Inclusion Criteria:\n\n* Enrolled student or employed administrative staff at LUMS.\n* 18 years of age or older.\n* Able to read and understand English.\n\nExclusion Criteria:\n\n* Individuals with any formal education or professional training in medicine, nursing, or any other healthcare profession.",true,"ALL","18 Years",{"count":77,"type":78},220,"ESTIMATED","INTERVENTIONAL",[81],"NA","This study is a randomized controlled trial (RCT) investigating whether access to a new LLM interface can improve medical triage and diagnostic accuracy for laypeople compared to access to a standard LLM interface. It addresses previous findings where laypeople using standard LLMs performed worse than those using conventional methods (e.g., web search) due to incomplete symptom sharing and poor interpretation of AI advice. To address this, the research tests a structured LLM system that proactively asks clinical history questions before providing a standardized, easy-to-read diagnostic output.",[84,85],"AI-Assisted Diagnosis","Large Language Models",[87,88,89],"LLMs","Diagnosis","Triage","2026-07-22",{"date":92,"type":93},"2026-07-27","ACTUAL",{"date":95,"type":78},"2026-07-25",{"date":97,"type":78},"2027-07-01",{"name":5,"class":6},1]