[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647883":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":26,"responsibleParty":42,"collaborators":10,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":10,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":75,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adult patients (≥18 years old) undergoing CAR-T cell therapy at IRCCS AOUBo",null,"Adult patients (≥18 years old) diagnosed with relapsed\u002Frefractory multiple myeloma or B-cell non-Hodgkin lymphoma who receive CAR-T cell therapy at the IRCCS AOUBo during the study periods",[13],{"name":14,"affiliation":5,"role":15},"Zeno Adrien Igor Pasquini","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Zeno Adrien Igor Pasquini, MD","CONTACT","+39 051 214 3752","zeno.pasquini@aosp.bo.it",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},"Maddalena Giannella, MD, PhD","+39 051 2143199","maddalena.giannella@unibo.it",[27],{"facility":5,"status":10,"city":28,"state":29,"zip":30,"country":29,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Bologna","Italy","40138","IT",{"type":33,"coordinates":34},"Point",[35,36],11.33875,44.49381,{"lat":36,"lon":35},[39,40,41],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},{"name":18,"role":15,"phone":10,"phoneExt":10,"email":10},{"type":43,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100647883","infections-in-patients-treated-with-car-t-100647883",false,"NCT07713511","INfections in Patients Treated With CAR-T","INfections in Patients Treated With CAR-T: Analysis of Incidence, Risk Factors, and Management Strategies","IN-CART","Inclusion Criteria:\n\n* Diagnosis of relapsed\u002Frefractory multiple myeloma or B-cell non-Hodgkin lymphoma, including diffuse large B-cell lymphoma, not otherwise specified (DLBCL-NOS), high-grade B-cell lymphoma (HGBCL), primary mediastinal B-cell lymphoma (PMBCL), follicular lymphoma (FL) and mantle cell lymphoma (MCL)\n* Receipt of CAR-T infusion at IRCCS AOUBo\n* Age ≥18 years at the time of CAR-T infusion\n* Signed informed consent\n\nExclusion Criteria:\n\n* None","ALL","18 Years",{"count":55,"type":56},290,"ESTIMATED","OBSERVATIONAL","This study includes adults with multiple myeloma or B-cell lymphoma who were\u002Fwill be treated with CAR-T cell therapy at the IRCCS Azienda Ospedaliero-Universitaria di Bologna. The aim is to better understand infections that may occur during the first year after CAR-T treatment, including how often they happen, their causes, and factors that may increase the risk. The study will use information from patients treated in the past and from newly enrolled patients. For some patients who develop fever after CAR-T therapy, a rapid molecular blood test will be used alongside standard tests to help identify bloodstream infections more quickly and support timely clinical care.",[60,61,62,63,64],"Relapsed Multiple Myeloma","Refractory Multiple Myeloma","B-Cell Non-Hodgkin Lymphoma","Bloodstream Infections","CAR-T Cell Therapy",[66,67,64,68,69,70,71,72,73,74],"Multiple Myeloma","B-cell Non-Hodgkin Lymphoma","CAR-T Cell Infusion","Bloodstream Infection","Infectious Complications","CAR-T","ddPCR blood test","Cytokine Release Syndrome","CRS","NOT_YET_RECRUITING","2026-07-17",{"date":78,"type":79},"2026-07-20","ACTUAL",{"date":81,"type":56},"2026-11-01",{"date":83,"type":56},"2029-04-30",{"name":5,"class":6},1]