[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100653376":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":11,"studyPopulation":16,"armGroups":11,"interventions":11,"overallOfficials":11,"centralContacts":11,"locations":17,"responsibleParty":36,"collaborators":11,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":11,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":11,"studyType":52,"phases":11,"briefSummary":53,"conditions":54,"keywords":11,"overallStatus":57,"whyStopped":11,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"Fondazione IRCCS Policlinico San Matteo di Pavia","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Prevalence of autoimmune or immune-mediated conditions during the menopausal transition",null,"At the baseline visit (cross-sectional assessment)",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":14,"timePerspective":15,"maskingInfo":11},"COHORT","CROSS_SECTIONAL","Women referred to the menopause clinic for the management of climacteric symptoms, perimenopausal menstrual irregularities, and\u002For the prevention of menopause-associated conditions, alongside women referred to an internal medicine outpatient clinic dedicated to the diagnosis and treatment of immune-mediated gastrointestinal diseases",[18],{"facility":5,"status":11,"city":19,"state":20,"zip":21,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Pavia","Lombardy","27100","Italy","IT",{"type":25,"coordinates":26},"Point",[27,28],9.15917,45.19205,{"lat":28,"lon":27},[31],{"name":32,"role":33,"phone":34,"phoneExt":11,"email":35},"Rossella Nappi, MD","CONTACT","0382501561","r.nappi@smatteo.pv.it",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Rossella Nappi","Principal Investigator","100653376","inflammation-autoimmunity-and-healthy-ageing-in-menopause-transition-an-observational-cross-sectional-study-100653376",false,"NCT07784400","Inflammation, Autoimmunity and Healthy Ageing in Menopause Transition. An Observational, Cross-sectional Study","Inclusion Criteria:\n\n* women aged 40-60 years referred to the menopause and gastroenterological outpatient clinic\n\nExclusion Criteria:\n\n* inability to give consent","FEMALE","40 Years","60 Years",{"count":50,"type":51},300,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the prevalence of autoimmune or immune-mediated conditions in women during the menopausal transition (aged 40-60 years). The main questions it aims to answer are:\n\n* What is the prevalence of autoimmune or immune-mediated conditions in women aged 40-60 years across different reproductive stages?\n* How do inflammatory markers, resilience, lifestyle factors, and allostatic load scores relate to menopause-related symptoms and general health?\n\nParticipants will complete evaluations, provide samples for clinical, immunological, and biochemical markers, and undergo assessments to analyze symptom burden and psychosocial determinants during the menopausal transition.",[55,56],"Autoimmune Diseases","Menopause","NOT_YET_RECRUITING","2026-08-20",{"date":60,"type":61},"2026-08-25","ACTUAL",{"date":63,"type":51},"2026-09",{"date":65,"type":51},"2028-09",{"name":5,"class":6},1]