[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100395773":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":17,"studyPopulation":21,"armGroups":17,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":31,"responsibleParty":48,"collaborators":17,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":17,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":17,"studyType":64,"phases":17,"briefSummary":65,"conditions":66,"keywords":17,"overallStatus":33,"whyStopped":17,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Huashan Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"cerebrovascular disease","Magnetic resonance images will be used to determine the severity of white matter hyperintensity, using the Scheltens scale. Score 2 or more is abnormal.","5 years",[14],{"measure":15,"description":16,"timeFrame":12},"changes in cognitive function","The Mini-Mental State Examination (MMSE) will be used to assess the changes in cognitive function.The MMSE has a maximum score of 30 points. The scores are generally grouped as follows:\n\n25-30 points: normal cognition 21-24 points: mild dementia 10-20 points: moderate dementia 9 points or lower: severe dementiaThe Mini-Mental State Examination (MMSE) will be used to assess the changes in cognitive function.The MMSE has a maximum score of 30 points. The scores are generally grouped as follows: 25-30 points: normal cognition 21-24 points: mild dementia 10-20 points: moderate dementia 9 points or lower: severe dementia",null,{"allocation":17,"interventionModel":17,"interventionModelDescription":17,"primaryPurpose":17,"observationalModel":19,"timePerspective":20,"maskingInfo":17},"COHORT","PROSPECTIVE","maintenance hemodialysis patients",[23],{"name":24,"affiliation":5,"role":25},"Jing Chen","PRINCIPAL_INVESTIGATOR",[27],{"name":24,"role":28,"phone":29,"phoneExt":17,"email":30},"CONTACT","862152889325","chenjing1998@fudan.edu.cn",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Shanghai","Shanghai Municipality","200040","China","CN",{"type":40,"coordinates":41},"Point",[42,43],121.45806,31.22222,{"lat":43,"lon":42},[46],{"name":47,"role":28,"phone":17,"phoneExt":17,"email":17},"Qian Zhang",{"type":25,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"Chen Jing","Professor","100395773","influencing-factors-of-cerebrovascular-disease-and-cognition-in-hemodialysis-patients-100395773",false,"NCT04433455","Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients","Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients: an Observational Study","Inclusion Criteria:\n\n1. maintenance hemodialysis patients who are younger than 85 years old and older than 50 years old, regardless of gender\n2. dialysis vintage is greater than 3 months;\n\nExclusion Criteria:\n\n1. Those with severe infection and anemia (Hb \\\u003C60g \u002F L);\n2. Those with severe mental illness, metabolic diseases and immune system diseases;\n3. Patients with abnormal liver function","ALL","50 Years","85 Years",{"count":62,"type":63},20,"ESTIMATED","OBSERVATIONAL","In this observational study, the investigators evaluate the influencing factors of cerebrovascular disease and cognition in hemodialysis patients.",[67,68,69],"Hemodialysis","Cognitive Impairment","Cerebrovascular Disorders","2026-09-20",{"date":72,"type":73},"2026-09-23","ACTUAL",{"date":75,"type":73},"2020-06-01",{"date":77,"type":63},"2026-12-31",{"name":5,"class":6},1]