[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601120":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":37,"responsibleParty":55,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":25,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":25,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Information Letter","ACTIVE_COMPARATOR","This arm provides an information letter about Lynch syndrome and genetic services.",[13],"Behavioral: Information Letter",{"label":15,"type":16,"description":17,"interventionNames":18},"Information Letter and Booklet","EXPERIMENTAL","This arm provides an information letter with a booklet about Lynch syndrome and genetic services.",[19],"Behavioral: Information Letter and Booklet",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","an information letter with a booklet for at-risk families highlighting implications of family history, testing considerations, steps for genetic testing, and potential costs.",[15],null,{"type":22,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"an information letter with basic information about LS and implications of counseling and testing of LS, and a few websites for more information and locating genetic counselors.",[9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Haoyang Yan, PhD","CONTACT","205-914-2249","LSPilotStudy@uabmc.edu",{"name":36,"role":32,"phone":33,"phoneExt":25,"email":34},"Kaylee Burgan, MS",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"UAB","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-86.80249,33.52066,{"lat":50,"lon":49},[53],{"name":54,"role":32,"phone":33,"phoneExt":25,"email":34},"study team",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Haoyang Yan","assistant professor",[60],{"name":61,"class":62},"National Cancer Institute (NCI)","NIH","100601120","initial-testing-of-a-behavioral-intervention-about-genetic-services-for-families-at-risk-of-lynch-syndrome-100601120",false,"NCT07106359","Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome","A Randomized Controlled Pilot Trial of a Behavioral Intervention to Increase Uptake of Genetic Services Among Relatives at Risk of Lynch Syndrome","Probands Inclusion Criteria:\n\n* English speaking\n* at least 18 years old\n* have had genetic testing for Lynch syndrome (LS)\n* do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)\n\nClinical Trial Participants Inclusion Criteria:\n\n* English-speaking\n* at least 18 years old\n* a blood relative of a patient who was diagnosed with LS\n* potentially at risk for LS\n* have not scheduled or had pre-test genetic counseling or genetic testing for LS\n* do not have a personal history of a cancer (excluding non-melanoma skin cancer)\n* do not have a condition that would interfere with their ability to provide informed consent and complete study activities (e.g., cognitive dysfunction evaluated using clinical judgment during screening)",true,"ALL","18 Years",{"count":74,"type":75},185,"ESTIMATED","INTERVENTIONAL",[78],"NA","The purpose of the study is to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services. Untested relatives of patients with Lynch syndrome will be recruited to complete a baseline survey and will be randomized to receive either the an information letter or an information letter plus a booklet. Two follow-up surveys will be administered over the span of 6 months. Participants will also be invited to join an optional exit interview to provide feedback.",[81,82,83,84,85,86],"Cascade Testing","Lynch Syndrome","Decision Making","Colorectal Cancer","Uterine Cancer","Cancer Prevention","2026-07-20",{"date":89,"type":90},"2026-07-21","ACTUAL",{"date":92,"type":90},"2025-09-15",{"date":94,"type":75},"2027-10-31",{"name":5,"class":6},1]