[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648797":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":35,"centralContacts":44,"locations":50,"responsibleParty":76,"collaborators":79,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":84,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":35,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":108,"overallStatus":53,"whyStopped":35,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"University College London Hospitals","OTHER",[8,15,20,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Combined Exposure and Response Prevention and Habit Reversal","EXPERIMENTAL","Participants allocated to this arm will receive a 12-week individual psychological intervention integrating Exposure and Response Prevention (ERP) and Habit Reversal Training (HRT). ERP will involve planned exposure to obsessional fears, distress, sensory discomfort, premonitory urges, and \"not-just-right\" experiences while reducing compulsions, avoidance, reassurance seeking, and other safety behaviours. HRT will include awareness training, identification of premonitory urges and tic-related cues, development and practice of competing responses, and strategies to support generalisation. Sessions will last approximately 50 minutes and will be delivered face-to-face or remotely.",[13,14],"Behavioral: Exposure and Response Prevention (ERP)","Behavioral: Habit Reversal Training (HbRT",{"label":16,"type":17,"description":18,"interventionNames":19},"Standardised Exposure and Response Prevention","ACTIVE_COMPARATOR","Participants allocated to this arm will receive a 12-week individual psychological intervention based on Exposure and Response Prevention (ERP). Treatment will involve gradual and systematic exposure to obsessional fears, distress, sensory discomfort, premonitory urges, and \"not-just-right\" experiences while refraining from compulsions, avoidance, reassurance seeking, and other safety behaviours. The intervention aims to reduce obsessive-compulsive symptoms by promoting inhibitory learning and increasing tolerance of uncertainty and internal experiences. Sessions will last approximately 50 minutes and will be delivered face-to-face or remotely.",[13],{"label":21,"type":17,"description":22,"interventionNames":23},"Standardised Habit Reversal","Participants allocated to this arm will receive a 12-week individual psychological intervention based on Habit Reversal Training (HbRT). Treatment will include awareness training to improve recognition of tics and premonitory urges, identification of antecedents and contextual triggers, development and practice of competing responses, and strategies to promote generalisation of skills to everyday settings. The intervention aims to reduce tic severity and improve voluntary tic management. Sessions will last approximately 50 minutes and will be delivered face-to-face or remotely.",[14],{"label":25,"type":17,"description":26,"interventionNames":27},"Psychoeducation \u002F Supportive Intervention","Participants allocated to this arm will receive a 12-week individual psychological intervention consisting of psychoeducation and supportive therapy. Sessions will provide information about obsessive-compulsive disorder, tic disorders, Tourettic obsessive-compulsive disorder, stress, and wellbeing, together with supportive discussion and general problem-solving. This intervention will not include structured Exposure and Response Prevention, Habit Reversal Training, or other targeted behavioural techniques. Sessions will last approximately 50 minutes and will be delivered face-to-face or remotely.",[28],"Behavioral: Psychoeducation and Supportive Intervention",[30,36,40],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"BEHAVIORAL","Exposure and Response Prevention (ERP)","Exposure and Response Prevention (ERP) is a behavioural intervention that involves gradual and systematic exposure to obsessional fears, distress, sensory discomfort, premonitory urges, and \"not-just-right\" experiences while refraining from compulsions, avoidance, reassurance seeking, and other safety behaviours. Treatment is delivered individually over 12 weekly 50-minute sessions, either face-to-face or remotely.",[9,16],null,{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Habit Reversal Training (HbRT","Habit Reversal Training (HbRT) is a behavioural intervention that includes awareness training, identification of premonitory urges and antecedents to tic expression, development and practice of competing responses, and strategies to generalise skills across settings. Treatment is delivered individually over 12 weekly 50-minute sessions, either face-to-face or remotely.",[9,21],{"type":31,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"Psychoeducation and Supportive Intervention","Psychoeducation and Supportive Therapy consists of structured education about obsessive-compulsive disorder, tic disorders, Tourettic obsessive-compulsive disorder, stress, and wellbeing, together with supportive discussion and general problem-solving. The intervention does not include Exposure and Response Prevention, Habit Reversal Training, or other targeted behavioural techniques. Treatment is delivered individually over 12 weekly 50-minute sessions, either face-to-face or remotely.",[25],[45],{"name":46,"role":47,"phone":48,"phoneExt":35,"email":49},"Dipesh Patel, MPhil \u002F PhD","CONTACT","+44 (0)20 3456 7890","dipesh.patel.23@ucl.ac.uk",[51,66],{"facility":52,"status":53,"city":54,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"University College London Hospitals NHS Foundation Trust","RECRUITING","London","WC1N 3BG","United Kingdom","UK",{"type":59,"coordinates":60},"Point",[61,62],-0.12574,51.50853,{"lat":62,"lon":61},[65],{"name":46,"role":47,"phone":48,"phoneExt":35,"email":49},{"facility":67,"status":53,"city":54,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"University College London Queen Square Institute of Neurology",{"type":59,"coordinates":69},[61,62],{"lat":62,"lon":61},[72,73],{"name":46,"role":47,"phone":48,"phoneExt":35,"email":49},{"name":74,"role":75,"phone":35,"phoneExt":35,"email":35},"Himanshu Tyagi, PhD","PRINCIPAL_INVESTIGATOR",{"type":75,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"Dipesh Patel","Dr",[80],{"name":81,"class":6},"University College, London","100648797","integrating-exposure-and-response-prevention-and-habit-reversal-techniques-to-treat-a-tourettic-subtype-of-obsessive-compulsive-disorder-tourettic-ocd-100648797",false,"NCT07725926","Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)","TORCH","Inclusion Criteria:\n\n1. Age 18 years or older\n2. All genders\n3. Confirmation of a primary diagnosis of either:\n\na. Tourettes Disorder \u002F Tourette Syndrome b. Persistent Motor or Vocal Tic Disorder \u002F Chronic Motor or Vocal Tic Disorder c. Provisional Tic Disorder \u002F Transient Motor Tics d. Other Specified Tic Disorder e. Unspecified Tic Disorder f. Obsessive-Compulsive Disorder \\[d\\] Participants taking psychotropic medication are eligible provided medication type and dose remain stable throughout the intervention period \\[e\\] Ability to provide sustained informed consent \\[f\\] A minimum score of 16 on YBOCS \\[g\\] A minimum score of 5 on the Premonitory Urge for Tics Scale (PUTS)\n\nExclusion Criteria:\n\n1. Substance misuse\n2. Current diagnosis of a personality disorder\n3. Schizophrenia\n4. Bipolar disorder\n5. Contraindications to participation in a trial (i.e., active suicidal ideations and\u002For requirement of an interpreter)\n6. Any psychiatric or neurological condition that, in the opinion of the investigators, would interfere with participation or interpretation of study outcomes.","ALL","18 Years","65 Years",{"count":93,"type":94},40,"ESTIMATED","INTERVENTIONAL",[97],"NA","Obsessive-Compulsive Disorder and Tic Disorders frequently co-occur, and a subgroup of patients - those with a Tourettic Subtype of OCD (TOCD) - present with concurrent obsessive-compulsive and tic symptoms. Existing psychological interventions typically target one condition or the other, but rarely both together. This study aims to test whether a combined psychological therapy integrating Exposure and Response Prevention (ERP) and Habit Reversal (HbRT) is more effective at reducing symptoms than either therapy delivered alone, in adults with TOCD.",[100,101,102,103,104,105,106,107],"Obsessive - Compulsive Disorder","Tic Disorder, Chronic Motor or Vocal","Tic Disorders","Tic Disorder, Combined Vocal and Multiple Motor","Tourette Disease","Tourette Disorder","Tourettes Syndrome","Gilles de la Tourette Syndrome",[109,102,110,111,112,113],"Obsessive-Compulsive Disorder","Tourette Syndrome","Tourettic Obsessive-Compulsive Disorder","Exposure and Response Prevention","Habit Reversal Training","2026-07-23",{"date":116,"type":117},"2026-07-27","ACTUAL",{"date":119,"type":117},"2026-07-08",{"date":121,"type":94},"2030-02-01",{"name":5,"class":6},2]