[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608900":3},{"organization":4,"outcomesModule":7,"designInfo":20,"detailedDescription":19,"studyPopulation":23,"armGroups":24,"interventions":30,"overallOfficials":38,"centralContacts":42,"locations":52,"responsibleParty":87,"collaborators":19,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":93,"acronym":19,"eligibilityCriteria":94,"healthyVolunteers":95,"sex":96,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":19,"studyType":102,"phases":19,"briefSummary":103,"conditions":104,"keywords":19,"overallStatus":55,"whyStopped":19,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Mayo Clinic","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":19},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Pathologic features","Will examine pathologic features from benign tissue to define features related to breast cancer (BC) risk.","Baseline (collection of blood or saliva sample)",{"measure":14,"description":15,"timeFrame":12},"Radiologic features","Will examine radiologic features from mammographic images at time of benign breast disease (BBD) to define features in mammogram images that predict BC risk among women who have a history of BBD. We will also assess whether these features predict BC risk among women without a history of BBD.",{"measure":17,"description":18,"timeFrame":12},"Molecular features","Will examine molecular features to understand how molecular features, including DNA damage and repair work in the breast tissues of women with BBD and how this might relate to risk of developing BC",null,{"allocation":19,"interventionModel":19,"interventionModelDescription":19,"primaryPurpose":19,"observationalModel":21,"timePerspective":22,"maskingInfo":19},"COHORT","PROSPECTIVE","Women who had a benign breast biopsy at Mayo Clinic between 2002 and 2022.",[25],{"label":26,"type":19,"description":27,"interventionNames":28},"Observational","Participants complete a questionnaire, undergo collection of saliva or blood samples, and have their medical records reviewed on study.",[29],"Other: Non-Interventional Study",[31],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"Non-Interventional Study","Non-interventional study",[26],[36,37],"Non-Interventional Observational Study","Noninterventional (Observational) Study",[39],{"name":40,"affiliation":5,"role":41},"Mark E. Sherman, MD","PRINCIPAL_INVESTIGATOR",[43,48],{"name":44,"role":45,"phone":46,"phoneExt":19,"email":47},"Laura Pacheco-Spann","CONTACT","904-953-0408","pachecospann.laura@mayo.edu",{"name":49,"role":45,"phone":50,"phoneExt":19,"email":51},"Clinical Trials Referral Office","855-776-0015","mayocliniccancerstudies@mayo.edu",[53,72],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Mayo Clinic in Florida","RECRUITING","Jacksonville","Florida","32224-9980","United States","US",{"type":62,"coordinates":63},"Point",[64,65],-81.65565,30.33218,{"lat":65,"lon":64},[68,70,71],{"name":44,"role":45,"phone":46,"phoneExt":19,"email":69},"PachecoSpann.Laura@mayo.edu",{"name":49,"role":45,"phone":50,"phoneExt":19,"email":51},{"name":40,"role":41,"phone":19,"phoneExt":19,"email":19},{"facility":73,"status":55,"city":74,"state":75,"zip":76,"country":59,"countryCode":60,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Mayo Clinic in Rochester","Rochester","Minnesota","55905",{"type":62,"coordinates":78},[79,80],-92.4699,44.02163,{"lat":80,"lon":79},[83,84,85],{"name":44,"role":45,"phone":46,"phoneExt":19,"email":47},{"name":49,"role":45,"phone":50,"phoneExt":19,"email":51},{"name":86,"role":41,"phone":19,"phoneExt":19,"email":19},"Celine M. Vachon, PhD",{"type":88,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100608900","integrating-molecular-pathology-radiology-and-genetics-to-improve-breast-cancer-risk-100608900",false,"NCT07207564","Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk","Inclusion Criteria:\n\n* Female patients, ages 18 to 100 years\n* Had a benign breast biopsy at Mayo Clinic between 2002-2022\n\nExclusion Criteria:\n\n* All male patients\n* Prior or concomitant diagnosis of BC\n* Diagnosis of BC within six months of benign breast disease\n* Denial of research authorization\n* Concurrent or post-biopsy bilateral prophylactic mastectomy",true,"FEMALE","18 Years","100 Years",{"count":100,"type":101},4500,"ESTIMATED","OBSERVATIONAL","The purpose of this research is to better understand how benign breast diseases might lead to breast cancer, focusing on genetic factors and including a diverse range of participants to improve future diagnosis and treatment.",[105],"Breast Carcinoma","2026-08-25",{"date":108,"type":109},"2026-08-27","ACTUAL",{"date":111,"type":109},"2025-08-28",{"date":113,"type":101},"2030-06-30",{"name":5,"class":6},2]