[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647448":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":42,"collaborators":10,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":10,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Andijan State Medical Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients With Hypothyroidism",null,"Adult patients with a previously established diagnosis of hypothyroidism who will undergo clinical examination, anthropometric assessment, ultrasonographic evaluation of the liver, pancreas and kidneys, functional assessment of the musculoskeletal system, and laboratory testing according to the study protocol.",[13],"Diagnostic Test: Comprehensive Morphometric and Functional Assessment",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Comprehensive Morphometric and Functional Assessment","Participants will undergo a standardized diagnostic assessment including clinical evaluation, anthropometric measurements, ultrasonographic examination of the liver, pancreas, and kidneys, functional",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Abdukhalim Kh. Abdurakhimov, PhD","CONTACT","+998941010091","abduhalim@adti.uz",[27],{"facility":5,"status":10,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Andijan","170127","Uzbekistan","UZ",{"type":33,"coordinates":34},"Point",[35,36],72.35067,40.78338,{"lat":36,"lon":35},[39],{"name":22,"role":23,"phone":40,"phoneExt":10,"email":41},"+9988941010091","abduhalimaka@mail.ru",{"type":43,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100647448","internal-organ-and-musculoskeletal-assessment-in-hypothyroidism-hypomorph-100647448",false,"NCT07707830","Internal Organ and Musculoskeletal Assessment in Hypothyroidism (HYPOMORPH)","Morphometric Characteristics of Internal Organs and Morphofunctional Status of the Musculoskeletal System in Patients With Hypothyroidism","HYPOMORPH","Inclusion Criteria:\n\n* Adults aged 18-59 years.\n* Previously established diagnosis of hypothyroidism.\n* Receiving routine outpatient or inpatient care at participating healthcare institutions.\n* Ability to undergo ultrasonographic, anthropometric, and functional assessments.\n* Provision of written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy or lactation.\n* History of thyroid malignancy.\n* Acute infectious or inflammatory disease at the time of enrollment.\n* Severe decompensated cardiovascular, hepatic, or renal disease preventing study procedures.\n* Neurological or musculoskeletal disorders that preclude functional testing.\n* Refusal or inability to provide informed consent.\n* Incomplete clinical or laboratory data.","ALL","18 Years",{"count":55,"type":56},500,"ESTIMATED","OBSERVATIONAL","This hospital-based observational cross-sectional study aims to investigate the morphometric characteristics of internal organs and the morphofunctional status of the musculoskeletal system in adult patients with previously diagnosed hypothyroidism. The study will evaluate ultrasonographic morphometric characteristics of the liver, pancreas, and kidneys, as well as anthropometric and functional characteristics of the musculoskeletal system. Associations between these outcomes and clinical characteristics, anthropometric parameters, physical activity, and laboratory findings will also be assessed. The study is expected to identify accessible clinical, anthropometric, and functional markers associated with morphometric and musculoskeletal changes in patients with hypothyroidism, thereby improving risk assessment and early detection of systemic involvement.",[60],"Hypothyroidism",[60,62,63,64,65,66,67,68,69,70,71,72],"Ultrasonography","Morphometry","Liver","Pancreas","Kidney","Musculoskeletal System","Anthropometry","Physical Function","Cross-Sectional Study","Physical Activity","Physical Inactivity","NOT_YET_RECRUITING","2026-07-14",{"date":76,"type":77},"2026-07-16","ACTUAL",{"date":79,"type":56},"2026-08-01",{"date":81,"type":56},"2028-12-31",{"name":5,"class":6},1]