[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525847":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":60,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":66,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":26,"overallStatus":46,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Anhui Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"real stimulation","ACTIVE_COMPARATOR","The central electrode was placed over F3, with return electrodes at Fp1, Fz, F7 and C3. Fourteen 2-mA sessions (ramp-up and ramp-down periods of 15 and 15 seconds, respectively) were applied for 20 minutes per session, twice daily over 7 consecutive days, and the stimulus frequency was set as IAF.",[13],"Device: High-Definition Transcranial Alternating Current Stimulation (HD-tACS)",{"label":15,"type":16,"description":17,"interventionNames":18},"sham stimulation","SHAM_COMPARATOR","In the sham condition, tACS was delivered only during the ramp-up and ramp-down periods (15 and 15 s); no current was delivered during the 20-minute intervention. Participants will receive sham tACS twice daily for two weeks.",[19],"Device: sham High-Definition Transcranial Alternating Current Stimulation (HD-tACS)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","High-Definition Transcranial Alternating Current Stimulation (HD-tACS)","tACS is described as a non-invasive form of brain stimulation that uses a low-intensity, alternating current applied directly to the head through scalp electrodes.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"sham High-Definition Transcranial Alternating Current Stimulation (HD-tACS)","In the sham condition, tACS was delivered only during the ramp-up and ramp-down periods (15s and 15s); no current was delivered during the 20-minute intervention.",[15],[32],{"name":33,"affiliation":5,"role":34},"Yanghua Tian, PhD","STUDY_CHAIR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Kai Wang, PhD","CONTACT","+86-0551-62923704","wangkai1964@126.com",{"name":33,"role":38,"phone":42,"phoneExt":26,"email":43},"+8613955188448","ayfytyh@126.com",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":26,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Hefei","Anhui","China","CN",{"type":52,"coordinates":53},"Point",[54,55],117.28083,31.86389,{"lat":55,"lon":54},[58,59],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},{"name":33,"role":38,"phone":42,"phoneExt":26,"email":43},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","WANG KAI","Head, Dept of Neurology & Medical Psychology, Director, Cognitive Neuropsychology Lab, PRC","100525847","intervention-effect-of-high-definition-transcranial-alternating-current-stimulation-hd-tacs-on-non-suicidal-self-injury-nssi-100525847",false,"NCT06127056","Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)","Inclusion Criteria:\n\nThe patients were diagnosed by 2 or more senior clinical psychiatrists, meeting DSM-V criteria, and having 1 or more non-suicidal self-injurious behaviors in the last 6 months.\n\n12-18 years of age.\n\nThe medicine has not changed in the 4 weeks prior to or after this study, and if it has to be changed, the treatment medication is required to be at a subtherapeutic dosage level.\n\nExclusion Criteria:\n\nThe patient has suicidal ideation or has committed suicidal behavior\n\nT1 or T2 weighted phase magnetic resonance images show focal brain lesions\n\npatients had neurological disorders such as epilepsy, or serious physical illnesses\n\npatients had a history of substance abuse and drug dependence in the last 6 months or use of anticonvulsant drugs in the last 3 months\n\npatients had received radial cranial electrical stimulation or magnetic stimulation treatment in the last 3 months or received electroconvulsive therapy in the last 6 months\n\npatients had previous significant head trauma or EEG abnormality in the last 1 month\n\nbody-mounted devices unsuitable for treatment, such as pacemakers, artificial valves, and other metal implants.","ALL","12 Years","18 Years",{"count":74,"type":75},40,"ESTIMATED","INTERVENTIONAL",[78],"NA","To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging (MRI).",[81,82],"Transcranial Alternating Current Stimulation","Non-suicidal Self-injury","2026-07-20",{"date":85,"type":86},"2026-07-22","ACTUAL",{"date":88,"type":86},"2023-05-01",{"date":90,"type":75},"2026-08-30",{"name":5,"class":6},1]