[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646656":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":54,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":78,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intralesional 5% Dextrose Injection","EXPERIMENTAL","Participants in this group will receive ultrasound-guided 5% dextrose injection to the supraspinatus enthesis. In addition, intralesional 5% dextrose injection will be applied to the partial rotator cuff tear using the peppering technique. Injections will be performed in three treatment sessions at 21-day intervals. All participants will receive a home-based exercise program after completion of the injection treatments.",[13],"Procedure: Intralesional 5% Dextrose Injection",{"label":15,"type":16,"description":17,"interventionNames":18},"Perilesional 5% Dextrose Injection","ACTIVE_COMPARATOR","Participants in this group will receive ultrasound-guided 5% dextrose injection to the supraspinatus enthesis. In addition, perilesional 5% dextrose injection will be applied around the partial rotator cuff tear using the peppering technique. Injections will be performed in three treatment sessions at 21-day intervals. All participants will receive a home-based exercise program after completion of the injection treatments.",[19],"Procedure: Perilesional 5% Dextrose Injection",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Ultrasound-guided 5% dextrose injection will be applied to the supraspinatus enthesis and additionally into the partial tear lesion using the peppering technique. A volume of 0.1-0.2 cc will be administered to each point. The treatment will consist of three sessions performed at 21-day intervals.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Ultrasound-guided 5% dextrose injection will be applied to the supraspinatus enthesis and additionally around the partial tear lesion using the peppering technique. A volume of 0.1-0.2 cc will be administered to each point. The treatment will consist of three sessions performed at 21-day intervals.",[15],[30],{"name":31,"affiliation":5,"role":32},"ESRA Ülgen Kıratlıoğlu","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Esra Ülgen Kıratlıoğlu, MD","CONTACT","+905079614194","esraulgen@gmail.com",[40],{"facility":41,"status":42,"city":43,"state":25,"zip":25,"country":44,"countryCode":25,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Ankara Bilkent City Hospital, Physical Medicine and Rehabilitation Hospital","RECRUITING","Ankara","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],32.85427,39.91987,{"lat":49,"lon":48},[52],{"name":53,"role":36,"phone":37,"phoneExt":25,"email":38},"Esra Ülgen Kıratlıoğlu",{"type":32,"investigatorFullName":53,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"MD","100646656","intralesional-versus-perilesional-5-dextrose-injection-in-partial-rotator-cuff-tears-100646656",false,"NCT07688902","Intralesional Versus Perilesional 5% Dextrose Injection in Partial Rotator Cuff Tears","Comparison of Clinical and Ultrasonographic Outcomes of Intralesional and Perilesional 5% Dextrose Injection in Patients With Partial Rotator Cuff Tears: A Prospective Randomized Double-Blind Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of partial rotator cuff tear by a specialist physician after appropriate clinical examination and imaging evaluation\n* Shoulder pain and functional limitation lasting for at least 3 months\n* Clinically confirmed shoulder impingement findings, defined as at least one positive test among Neer, Hawkins-Kennedy, or painful arc tests\n* Age between 18 and 75 years\n* Ability to comply with the study procedures and attend follow-up visits regularly\n* Willingness to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* Advanced cognitive impairment or dementia preventing reliable completion of questionnaires\n* Refusal to participate in the study or inability to provide informed consent\n* Full-thickness rotator cuff tear\n* Major tendon pathology other than the supraspinatus tendon, such as full-thickness subscapularis tear or biceps tendon rupture\n* Advanced acromioclavicular joint osteoarthritis, marked impingement, or marked adhesive capsulitis\n* Advanced glenohumeral joint arthritis\n* Active infection, cellulitis, or dermatologic lesion at the injection site\n* Bleeding diathesis or anticoagulant use\n* Known allergy or intolerance to dextrose injection\n* Intra-articular shoulder injection, including steroid, platelet-rich plasma, or prolotherapy, within the last 3 months\n* Previous shoulder surgery\n* Uncontrolled diabetes mellitus, defined as HbA1c \\>8.5%, or severe endocrine or metabolic disorder\n* Immunosuppression or active infection\n* Rheumatologic shoulder involvement\n* Neurological disease affecting shoulder movements\n* Pregnancy\n* Active malignancy","ALL","18 Years","75 Years",{"count":67,"type":68},30,"ESTIMATED","INTERVENTIONAL",[71],"NA","This prospective, randomized, double-blind controlled clinical trial aims to compare the clinical and ultrasonographic outcomes of intralesional and perilesional 5% dextrose injection in patients with partial rotator cuff tears. Eligible participants will be randomized into two parallel groups. Both groups will receive ultrasound-guided 5% dextrose injection to the supraspinatus enthesis. In addition, one group will receive intralesional 5% dextrose injection, while the other group will receive perilesional 5% dextrose injection using the peppering technique. Injections will be performed in three treatment sessions at 21-day intervals. All participants will receive a home-based exercise program after completion of the injection treatments. Clinical outcomes will be assessed at baseline, 9 weeks, and 12 weeks after treatment, and ultrasonographic outcomes will be assessed at baseline and 12 weeks.",[74,75,76,77],"Partial Rotator Cuff Tears","Rotator Cuff Tendinopathy","Shoulder Pain Chronic","Supraspinatus Tendon Tear",[79,80,81,82,83,84,85,86,87,88],"Dextrose injection","Prolotherapy","Intralesional injection","Perilesional injection","Partial rotator cuff tear","Supraspinatus tendon","Ultrasound-guided injection","Shoulder Pain and Disability Index","Numeric Rating Scale","Ultrasonography","2026-06-30",{"date":91,"type":92},"2026-07-07","ACTUAL",{"date":94,"type":92},"2025-02-01",{"date":96,"type":68},"2026-10-01",{"name":5,"class":6},1]