[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640439":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":39,"centralContacts":43,"locations":50,"responsibleParty":68,"collaborators":23,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":23,"eligibilityCriteria":78,"healthyVolunteers":75,"sex":79,"minAge":80,"maxAge":23,"enrollmentInfo":81,"targetDuration":23,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":53,"whyStopped":23,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Istanbul University - Cerrahpasa","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Dual-Task IMT","EXPERIMENTAL","Participants will receive IMT combined with simultaneous cognitive tasks for 8 weeks (5 days\u002Fweek, 2 sessions\u002Fday). One session per week will be supervised, and the remaining sessions will be performed via telerehabilitation. Training intensity will be set at 50% of MIP and adjusted weekly.",[13],"Behavioral: Dual-Task IMT",{"label":15,"type":10,"description":16,"interventionNames":17},"Standard IMT","Participants will receive IMT alone for 8 weeks (5 days\u002Fweek, 2 sessions\u002Fday). One session per week will be supervised, and the remaining sessions will be performed via telerehabilitation. Training intensity will be set at 50% of MIP and adjusted weekly.",[18],"Behavioral: IMT",{"label":20,"type":21,"description":22,"interventionNames":23},"Control (Usual Care)","NO_INTERVENTION","Participants will not receive any additional intervention and will continue their usual medical care. Assessments will be performed at baseline and after 8 weeks.",null,[25,33],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"BEHAVIORAL","IMT will be applied using a threshold loading device at 50% of MIP for 8 weeks (5 days\u002Fweek, 2 sessions\u002Fday, 15 minutes each). One session per week will be supervised, and the remaining sessions will be performed via telerehabilitation. During IMT, participants will simultaneously perform cognitive tasks targeting attention, memory, and executive functions, which will be varied weekly to minimize learning effects.",[9],[30,31,32],"Cognitive-Motor IMT","Cognitive-Motor Dual-Task","Dual-Task",{"type":26,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"IMT","IMT will be applied using a threshold loading device at 50% of MIP for 8 weeks (5 days\u002Fweek, 2 sessions\u002Fday, 15 minutes each). One session per week will be supervised, and the remaining sessions will be performed via telerehabilitation. No additional cognitive task will be applied during training.",[15],[38],"Inspiratory Muscle Training",[40],{"name":41,"affiliation":5,"role":42},"Rengin Demir, Prof. Dr.","STUDY_DIRECTOR",[44],{"name":45,"role":46,"phone":47,"phoneExt":48,"email":49},"Vildan Fidanoglu, PT, MSc","CONTACT","212-924-24-44","1281","fzt.vildanbayraktaroglu@hotmail.com",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":23,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Istanbul University-Cerrahpaşa, Cardiology Institute","RECRUITING","Istanbul","Fatih","34098","Turkey (Türkiye)",{"type":59,"coordinates":60},"Point",[61,62],28.94966,41.01384,{"lat":62,"lon":61},[65],{"name":41,"role":46,"phone":66,"phoneExt":23,"email":67},"212-459-20-00","rengin.demir@iuc.edu.tr",{"type":69,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":72,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Vildan Fidanoglu","Principal Investigator","Halic University","100640439","investigation-of-the-effect-of-inspiratory-muscle-training-and-dual-task-inspiratory-muscle-training-on-cognitive-functions-in-heart-failure-100640439",false,"NCT07581587","Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure","Inclusion Criteria:\n\n* Age ≥ 40 years\n* Diagnosed with HF with reduced ejection fraction (HFrEF) according to the 2023 ESC HF Guidelines\n* Classified as NYHA functional class I-III\n* Clinically stable for at least 3 months and receiving stable pharmacological treatment\n* Able to read and understand Turkish\n* MoCA score ≥ 21\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Diagnosis of any neurological or neurodegenerative disease (e.g., Parkinson's disease, stroke, dementia, Alzheimer's disease)\n* Diagnosis of pulmonary disease (e.g., chronic obstructive pulmonary disease, obstructive sleep apnea)\n* Myocardial infarction within the last 6 months\n* Uncontrolled hypertension and\u002For diabetes mellitus\n* Severe valvular heart disease and\u002For uncontrolled arrhythmias\n* Orthopedic, visual, or hearing impairments that may prevent independent test completion\n* Inability to comply with study procedures or follow instructions","ALL","40 Years",{"count":82,"type":83},54,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure. It will also assess the effects of standard IMT and compare both approaches.\n\nThe main questions it aims to answer are:\n\n* Does dual-task IMT improve cognitive function more than standard IMT or no intervention?\n* Does dual-task IMT improve respiratory function, inspiratory muscle strength, and exercise capacity?\n* What are the effects of dual-task IMT on symptoms such as dyspnea and fatigue, and on quality of life, anxiety, and depression?\n\nDual-task IMT, standard IMT, and a control group (no additional intervention) will be compared to determine which approach is more effective in patients with heart failure (HF).\n\nParticipants will:\n\n* Be randomly assigned to one of three groups: dual-task IMT, standard IMT, or control\n* Perform IMT training 5 days per week for 8 weeks (2 sessions per day, 15 minutes each) if assigned to an intervention group\n* Complete 1 supervised in-person session per week and 4 sessions via telerehabilitation if assigned to an intervention group\n* Undergo assessments before and after the 8-week intervention, including cognitive tests, respiratory function, exercise capacity, and symptom evaluations",[89],"Heart Failure",[91,34,92],"Inspiratory muscle training","Dual-task","2026-07-29",{"date":95,"type":96},"2026-07-30","ACTUAL",{"date":98,"type":96},"2026-07-27",{"date":100,"type":83},"2027-12",{"name":5,"class":6},1]