[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646172":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":55,"centralContacts":59,"locations":65,"responsibleParty":92,"collaborators":39,"id":95,"slug":96,"hasResults":97,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":103,"sex":104,"minAge":105,"maxAge":106,"enrollmentInfo":107,"targetDuration":39,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":122,"whyStopped":39,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"Karabuk University","OTHER",[8,14,19,24,29],{"label":9,"type":10,"description":11,"interventionNames":12},"Condition 1","EXPERIMENTAL","Dynamic contraction",[13],"Other: dynamic conraction",{"label":15,"type":10,"description":16,"interventionNames":17},"Condition 2","isometric contraction",[18],"Other: isometric contraction",{"label":20,"type":10,"description":21,"interventionNames":22},"Condition 3","Dynamic + EMS contraction",[23],"Other: dynamic and EMS contraction",{"label":25,"type":10,"description":26,"interventionNames":27},"Condition 4","Isometric + EMS Contraction",[28],"Other: isometric and EMS conraction",{"label":30,"type":10,"description":31,"interventionNames":32},"Condition 5","EMS contraction",[33],"Other: ems contraction",[35,40,43,47,51],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"dynamic conraction","Participants performed a dynamic back squat conditioning protocol on a Smith machine consisting of five sets of one repetition at 90% of one-repetition maximum (1RM), with 1 min of passive recovery between sets. Each repetition included a controlled descent to approximately 90° of knee flexion, an explosive concentric phase, a 2-s isometric hold at full knee extension, and a slow, controlled eccentric phase (Pincivero et al.). All repetitions were supervised to ensure proper technique. The protocol was selected based on previous evidence supporting high-intensity resistance exercise as an effective conditioning activity for inducing PAPE responses (Dobbs et al.).",[9],null,{"type":6,"name":16,"description":41,"armGroupLabels":42,"otherNames":39},"The isometric contraction protocol was conducted as described by Koźlenia and Domaradzki (2023) and Lim and Kong (2013). Participants assumed a squat position in a squat rack with the barbell fixed in place and the knee joint positioned at approximately 90° of flexion (Profitness 1030, Türkiye). The barbell was secured to the rack using safety pins, and participants were instructed to exert maximal force against the immovable bar to produce a MVIC. Each contraction lasted 3 seconds, and a total of 3 repetitions were performed with 2 min of rest between repetitions (Koźlenia \\& Domaradzki, 2023; Lim \\& Kong, 2013).",[15],{"type":6,"name":44,"description":45,"armGroupLabels":46,"otherNames":39},"dynamic and EMS contraction","Participants performed a dynamic back squat conditioning protocol on a Smith machine consisting of five sets of one repetition at 90% of one-repetition maximum (1RM), with 1 min of passive recovery between sets. In the DC-EMS condition, electromyostimulation (EMS) was applied simultaneously throughout the conditioning protocol. Each repetition included a controlled descent to approximately 90° of knee flexion, an explosive concentric phase, a 2-s isometric hold at full knee extension, and a slow, controlled eccentric phase (Pincivero et al.). All repetitions were supervised to ensure proper technique. The protocol was selected based on previous evidence supporting high-intensity resistance exercise as an effective conditioning activity for inducing PAPE responses (Dobbs et al.).",[20],{"type":6,"name":48,"description":49,"armGroupLabels":50,"otherNames":39},"isometric and EMS conraction","The isometric contraction protocol was conducted as described by Koźlenia and Domaradzki (2023) and Lim and Kong (2013). Participants assumed a squat position in a squat rack with the barbell fixed in place and the knee joint positioned at approximately 90° of flexion (Profitness 1030, Türkiye). The barbell was secured to the rack using safety pins, and participants were instructed to exert maximal force against the immovable bar to produce an MVIC. Each contraction lasted 3 seconds, and a total of three repetitions were performed with 2 min of rest between repetitions (Koźlenia \\& Domaradzki, 2023; Lim \\& Kong, 2013). In the MVIC-EMS condition, electromyostimulation (EMS) was applied simultaneously during each maximal voluntary isometric contraction.",[25],{"type":6,"name":52,"description":53,"armGroupLabels":54,"otherNames":39},"ems contraction","EMS was delivered bilaterally to the quadriceps using a portable stimulator (Compex Rehab 400, Compex Medical SA, Switzerland) with a biphasic symmetrical rectangular waveform (75 Hz, 450 μs). Four self-adhesive electrodes were placed over the vastus medialis and vastus lateralis muscles of both legs. Participants remained seated for 10 min with the knees flexed at approximately 90° and the hips flexed at approximately 110°, while receiving EMS without performing any voluntary contractions. Stimulation intensity was gradually increased to the highest level tolerated by each participant and maintained throughout the intervention (Paillard et al., 2008; Sofuoğlu et al., 2025).",[30],[56],{"name":57,"affiliation":5,"role":58},"Neslihan Akçay, Doctorate","STUDY_CHAIR",[60,64],{"name":57,"role":61,"phone":62,"phoneExt":39,"email":63},"CONTACT","+905468426671","neslihanozcan@karabuk.edu.tr",{"name":57,"role":61,"phone":39,"phoneExt":39,"email":39},[66],{"facility":5,"status":39,"city":67,"state":68,"zip":69,"country":70,"countryCode":39,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"Karabük","Turkey","78200","Turkey (Türkiye)",{"type":72,"coordinates":73},"Point",[74,75],32.62768,41.20488,{"lat":75,"lon":74},[78,79,81,84,86,88,90],{"name":57,"role":61,"phone":62,"phoneExt":39,"email":63},{"name":57,"role":80,"phone":39,"phoneExt":39,"email":39},"PRINCIPAL_INVESTIGATOR",{"name":82,"role":83,"phone":39,"phoneExt":39,"email":39},"Cem Sofuoğlu","SUB_INVESTIGATOR",{"name":85,"role":83,"phone":39,"phoneExt":39,"email":39},"Wolfgang Kemmler, Prof.Dr.",{"name":87,"role":83,"phone":39,"phoneExt":39,"email":39},"Andre Filipovic, Prof.Dr.",{"name":89,"role":83,"phone":39,"phoneExt":39,"email":39},"Metehan Yana, Doctorate",{"name":91,"role":83,"phone":39,"phoneExt":39,"email":39},"Erşan Arslan, Prof.Dr.",{"type":80,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":39,"oldOrganization":39},"Neslihan AKÇAY","Assoc. Prof. Dr.","100646172","isometric-vs-dynamic-squat-pre-loading-acute-pape-responses-100646172",false,"NCT07696026","Isometric vs. Dynamic Squat Pre-Loading: Acute PAPE Responses","Acute Post-Activation Performance Responses to Isometric and Dynamic Squat Pre-Loading Protocols: A Randomized Crossover Trial","IPP vs DPP","Inclusion Criteria:\n\n* Being healthy\n* Male volleyball athletes\n* Willing to maintain the intervention for all sessions\n\nExclusion Criteria:\n\n* Being under 18 years old\n* Having a chronic disease\n* Contraindications for exercise",true,"MALE","18 Years","25 Years",{"count":108,"type":109},22,"ESTIMATED","INTERVENTIONAL",[112],"NA","This randomized crossover study compared the acute post-activation performance responses to isometric and dynamic squat-based preconditioning protocols performed with and without electromyostimulation (EMS). Participants completed five randomized experimental conditions: maximal voluntary isometric contraction (MVIC), dynamic contraction (DC), MVIC+EMS, DC+EMS, and EMS only (O-EMS). Baseline and post-intervention assessments included countermovement jump (CMJ), countermovement jump with arm swing (CMJWH), zig-zag agility, and shooting speed, with post-tests conducted after a 4-minute recovery period. Perceptual responses, including ratings of perceived exertion (RPE), perceived discomfort (RPD), and fatigue (VAS), were recorded immediately after each protocol. All sessions were conducted between 14:00 and 16:00 under standardized conditions, with protocol order randomized and participants instructed to avoid strenuous exercise and food intake before testing.",[115,116,117],"Soccer","Performance","Contraction",[16,119,120,121],"dynamic contraction","squat","PAPE","NOT_YET_RECRUITING","2026-07-06",{"date":125,"type":126},"2026-07-10","ACTUAL",{"date":128,"type":109},"2026-08-01",{"date":130,"type":109},"2026-09-05",{"name":5,"class":6},1]