[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650370":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":30,"responsibleParty":44,"collaborators":46,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":20,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":20,"enrollmentInfo":58,"targetDuration":20,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":83,"whyStopped":20,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"International Centre for Diarrhoeal Disease Research, Bangladesh","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Micro-randomized JITAI cohort","EXPERIMENTAL","All participants enter a single 24-day micro-randomized cohort. At each eligible high-stress decision point, the platform independently randomizes with probability 0.50 between two momentary options.\n\nSupport prompt: The app immediately delivers one brief, culturally adapted coping-support message from a locked library. The message is matched to the participant's prespecified target behavior, can be read in under one minute, and does not disclose identity or community membership.\n\nNo prompt: No immediate coping-support message is delivered. The 10-minute micro-check and 45-minute follow-up are delivered on the same schedule in both options. No existing care is withheld, and participants retain access to study contact and distress-referral information.\n\nThe contrast is immediate support prompt versus no immediate support prompt. Thus, the estimated proximal effect combines receiving the message with its coping content; these components are not estimated separately.",[13],"Behavioral: Just-in-Time Adaptive Support Message",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Just-in-Time Adaptive Support Message","A brief, culturally adapted, in-app behavioral support message delivered on the participant's own smartphone immediately after randomization at an eligible high-stress decision point. Content is finalized and locked before the trial following a formative cultural adaptation phase and review by a Community Advisory Board. The message is matched to the participant's locked target behavior and may include grounding, urge-delay, motivational, values-based, environmental, substitute-action, social-support, or location-change strategies. It is nonjudgmental, action-oriented, designed to be read in under one minute, and requires no immediate response. At decision points randomized to the no-message option, no immediate support message is delivered.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Pritom K. Das","PRINCIPAL_INVESTIGATOR",[26],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","+8802222277144","pritom.das@icddrb.org",[31],{"facility":32,"status":20,"city":33,"state":20,"zip":20,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)","Dhaka","Bangladesh","BD",{"type":37,"coordinates":38},"Point",[39,40],90.40744,23.7104,{"lat":40,"lon":39},[43],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},{"type":45,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[47],{"name":48,"class":6},"Global Affairs Canada","100650370","just-in-time-support-for-smoking-vaping-and-eating-urges-during-high-stress-moments-among-gender-and-sexual-minority-adults-in-dhaka-100650370",false,"NCT07746492","Just-in-Time Support for Smoking, Vaping, and Eating Urges During High-Stress Moments Among Gender and Sexual Minority Adults in Dhaka","A Digital Real-Time Support for Stress-Induced Smoking and Unhealthy Eating Among Gender and Sexual Minorities in Dhaka","Inclusion Criteria:\n\n* Age 18 years or older\n* Self-identifies as a gender and\u002For sexual minority person\n* Resides in Dhaka at enrolment and expects to remain in Dhaka throughout the 24-day assessment period\n* Reports at least one qualifying behaviour on average at least 3 days per week during the past month: (a) smoking or vaping, or (b) eating primarily in response to stress, anxiety, or emotional distress\n* Owns a personal Android or iOS smartphone compatible with the study platform that is used solely by the participant and is not shared with others\n* Able to read, understand, and respond to simple Bangla text\n* Able to operate the study app independently after a structured onboarding session\n* Willing to complete five scheduled app-based momentary assessments per day for 24 days and additional brief follow-up assessments after randomized decision points\n* Provides written informed consent\n\nExclusion Criteria:\n\n* Currently participating in another behavioural or pharmacological intervention study targeting smoking, vaping, or eating behaviour\n* Has a severe or unstable psychiatric condition that, based on screening and review by the study clinician, would make participation in the repeated daily assessment protocol unsafe\n* Is unable to operate the study app independently after structured onboarding","ALL","18 Years",{"count":59,"type":60},115,"ESTIMATED","INTERVENTIONAL",[63],"NA","Gender and sexual minority adults in Bangladesh experience high levels of stigma-related stress. Acute stress can trigger strong, affect-driven urges to smoke, vape, or engage in stress-attributed eating. These urges can rise and fall within minutes to hours, operating outside the reach of conventional clinic-based interventions delivered days or weeks later.\n\nThis pilot micro-randomized trial (MRT) evaluates whether delivering a brief, culturally adapted support message via smartphone during moments of high self-reported stress reduces the intensity of the urge for the participant's pre-specified target behaviour, relative to no message. Over a 24-day period, 115 participants will be scheduled for up to 5 ecological momentary assessments (EMA) per day. Whenever a participant reports an acute stress level of 5 or higher (0 to 10 scale) and satisfies pre-specified privacy, safety, behavioural, and spacing criteria, the app randomizes with probability 0.5 to deliver either a brief support message or no message. By contributing multiple randomized decision points over time, each participant serves as their own micro-control.\n\nThe primary outcome is the intensity of the urge for the participant's pre-specified target behaviour, measured 45 to 60 minutes after randomization. An exploratory urge assessment is also collected 10 minutes after randomization; comparing the two time points will help establish whether the support message's effect is immediate, delayed, or both, and will inform the choice of follow-up window for a future, fully powered trial. Prior to trial launch, all EMA items, message content, notification logic, and digital safety protocols will be developed and tested with community members, reviewed by a Community Advisory Board, and locked.\n\nAs a pilot optimization trial, its objectives are to estimate the short-term causal effect of the prompt, to identify the contexts in which that effect is larger or smaller, and to establish whether momentary assessment and just-in-time intervention research can be delivered safely, privately, and acceptably in this high-stigma setting. The study does not evaluate long-term behavioural maintenance and does not claim to address the underlying structural stigma and discrimination that produce minority stress.",[66,67,68,69],"Tobacco Use","Electronic Cigarette Use","Emotional Eating","Stress, Psychological",[71,72,73,74,75,76,77,78,79,80,34,81,82],"micro-randomized trial","just-in-time adaptive intervention","ecological momentary assessment","mHealth","digital health","minority stress","smoking","vaping","stress-attributed eating","urge","gender and sexual minority","pilot optimization trial","NOT_YET_RECRUITING","2026-07-30",{"date":86,"type":87},"2026-08-05","ACTUAL",{"date":89,"type":60},"2026-09-01",{"date":91,"type":60},"2027-02-06",{"name":5,"class":6},1]