[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556475":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":11,"centralContacts":11,"locations":34,"responsibleParty":54,"collaborators":11,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":11,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":11,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":11,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Kemerovo State Medical University","OTHER",[8,14,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Ketamine 1","EXPERIMENTAL",null,[13],"Drug: Ketamine Hcl 50Mg\u002FMl Inj",{"label":15,"type":10,"description":11,"interventionNames":16},"Ketamine 3",[13],{"label":18,"type":19,"description":11,"interventionNames":20},"Control","PLACEBO_COMPARATOR",[21],"Other: Control",[23,28,31],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"DRUG","Ketamine Hcl 50Mg\u002FMl Inj","ketamine infusion at a dose of 0.1 mg\u002Fkg\u002Fhour for 16 hours",[9],{"type":24,"name":25,"description":29,"armGroupLabels":30,"otherNames":11},"ketamine infusion at a dose of 0.3 mg\u002Fkg\u002Fhour for 16 hours",[15],{"type":6,"name":18,"description":32,"armGroupLabels":33,"otherNames":11},"Without ketamine",[18],[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Artem Ivkin","RECRUITING","Kemerovo","Please Select","650066","Russia","RU",{"type":44,"coordinates":45},"Point",[46,47],86.10435,55.35417,{"lat":47,"lon":46},[50],{"name":36,"role":51,"phone":52,"phoneExt":11,"email":53},"CONTACT","+79030701880","ivkiaa@kemcardio.ru",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Evgeny Grigoryev","Head of the Department of Anesthesiology","100556475","ketamine-infusion-as-a-method-of-cerebral-protection-in-children-100556475",false,"NCT06525584","Ketamine Infusion as a Method of Cerebral Protection in Children","Ketamine Infusion in the Postoperative Period as a Method of Cerebral Protection in Children During Surgical Correction of Congenital Heart Defects","Inclusion Criteria:\n\n* age from 1 to 60 months\n* body weight from 3.5 to 20 kg\n* planned surgical intervention to correct a congenital heart defect (atrial or ventricular septal defect) with CPBё\n* the presence of informed consent for participation in the study signed by the child's legal representative\n\nExclusion Criteria:\n\n* lack of informed consent of the patient and parents to participate in the study,\n* emergency and urgent surgical interventions;\n* the presence of clinically significant anemia;\n* hypo-thermic during operation, episodes of desaturation in the perioperative period;\n* the presence of another congenital heart diseases besides the atrial or ventricular septal defect, as well as their combination;\n* a history of central nervous system diseases;\n* an installed pacemaker;\n* hemodynamic instability requiring preoperative pharmacological and\u002For mechanical support;\n* any episodes of cerebrovascular accidents in the history or periop-erative period;\n* the presence of a patient with severe concomitant diseases that worsen mental and somatic conditio;\n* acute infection and exacerbation of chronic infection in the perioperative period;\n* concomitant autoimmune diseases;\n* the presence of malignant neoplasms;\n* surgical complications in the postoperative period.","ALL","1 Month","5 Years",{"count":69,"type":70},196,"ESTIMATED","INTERVENTIONAL",[73],"NA","The study is devoted to the use of ketamine infusion in a subanesthetic dose in the postoperative period in children after surgical correction of congenital heart defects in children.",[76],"Brain Injuries","2026-08-13",{"date":79,"type":80},"2026-08-17","ACTUAL",{"date":82,"type":80},"2023-11-05",{"date":84,"type":70},"2028-12-30",{"name":5,"class":6},1]