[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656628":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":17,"studyPopulation":17,"armGroups":27,"interventions":40,"overallOfficials":17,"centralContacts":17,"locations":47,"responsibleParty":66,"collaborators":17,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":17,"enrollmentInfo":80,"targetDuration":17,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":92,"whyStopped":17,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":17},[9,13],{"measure":10,"description":11,"timeFrame":12},"Incidence of Adverse Events","Number of adverse events collected using a standardized adverse event reporting form (Unit: Count of events).","At baseline and 10-day of feeding",{"measure":14,"description":15,"timeFrame":16},"Adherence to the Intervention","Percentage of prescribed intervention sessions completed, assessed through adherence logs and system usage records (Unit: %)","From baseline to 10 days follow-up.",null,{"allocation":19,"interventionModel":20,"interventionModelDescription":17,"primaryPurpose":21,"observationalModel":17,"timePerspective":17,"maskingInfo":22},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":23,"maskingDescription":17,"whoMasked":24},"DOUBLE",[25,26],"PARTICIPANT","OUTCOMES_ASSESSOR",[28,34],{"label":29,"type":30,"description":31,"interventionNames":32},"Ketogenic feeding","EXPERIMENTAL","The ketogenic feeding will have a macronutrient composition of approximately 10% energy from carbohydrates, 25% energy from protein, and 65% energy from fat.",[33],"Behavioral: Ketogenic feeding",{"label":35,"type":36,"description":37,"interventionNames":38},"Standard feeding","PLACEBO_COMPARATOR","The participant will receive standard hospital care feeding.",[39],"Behavioral: Standard feeding",[41,44],{"type":42,"name":29,"description":31,"armGroupLabels":43,"otherNames":17},"BEHAVIORAL",[29],{"type":42,"name":35,"description":45,"armGroupLabels":46,"otherNames":17},"The participants will receive standard hospital care feeding.",[35],[48],{"facility":5,"status":17,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Birmingham","Alabama","35205","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-86.80249,33.52066,{"lat":58,"lon":57},[61],{"name":62,"role":63,"phone":64,"phoneExt":17,"email":65},"Robert Mankowski, PhD","CONTACT","2059963006","rmankowski@uabmc.edu",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Robert T Mankowski","Associate Professor","100656628","ketogenic-feeding-for-muscle-preservation-after-trauma-100656628",false,"NCT07827820","Ketogenic Feeding for Muscle Preservation After Trauma","Ketogenic Feeding to Preserve Muscle Mass in Middle-aged and Older Trauma Injury Patients","KETO TRAUMA","Inclusion Criteria:\n\n* Age 55 years and older\n* Traumatic injury\n* Expected to survive and at least 10-day stay in the hospital\n* Expected to be enterally fed for at least 10 days\n* Willingness to be randomized to either treatment group\n* Willingness to participate in all study procedures\n\nExclusion Criteria:\n\n* Failure to provide informed consent\n* Moribund\n* Vegeterian\u002Fvegan\n* Diagnosed dementia\n* Hip fracture, hip or knee replacement, or spinal surgery within past 4 months\n* Simultaneous participation in another intervention trial","ALL","55 Years",{"count":81,"type":82},20,"ESTIMATED","INTERVENTIONAL",[85],"NA","The purpose of this study is to determine whether a ketogenic diet, provided as tube feeding, compared with a standard hospital tube feeding, is safe and feasible and helps preserve muscle mass and improve metabolic health in adults aged 55 years and older hospitalized with traumatic injury.",[88],"Traumatic Injury",[90,91],"ketogenic feeding","traumatic injury","NOT_YET_RECRUITING","2026-09-14",{"date":95,"type":96},"2026-09-18","ACTUAL",{"date":98,"type":82},"2026-11-15",{"date":100,"type":82},"2029-08-31",{"name":5,"class":6},1]