[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591839":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":34,"locations":42,"responsibleParty":59,"collaborators":61,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":12,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":12,"enrollmentInfo":77,"targetDuration":12,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":92,"overallStatus":97,"whyStopped":12,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"University of Maryland, College Park","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Enhanced Treatment As Usual","NO_INTERVENTION","This site will receive enhanced treatment as usual (ETAU)-a one-day training for all CHWs on mental health screening, psychoeducation on mental health in HIV and impact on HIV care outcomes, and available referral pathways, and encouraged to use these skills during their home visits.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Khanya-Ekhaya","EXPERIMENTAL","The Khanya Ekhaya intervention includes an integration of several evidence-based treatment components, including problem solving therapy (PST), mindfulness, and behavioral activation (BA), previously tested and adapted for this context in clinic settings, as well as nature-informed cognitive-behavioral and mindfulness strategies to promote well-being. Aims 1-2 informed Khanya-Ekhaya adaptation.",[18],"Behavioral: Khanya-Ekhaya",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"BEHAVIORAL","The Khanya Ekhaya intervention includes an integration of several evidence-based treatment components, including motivational interviewing (MI), problem solving therapy (PST), and behavioral activation (BA), previously tested and adapted for this context in clinic settings, as well as cognitive-behavioral and mindfulness strategies that target rumination and negative thinking patterns. Aims 1-2 will inform Khanya-Ekhaya adaptation, including intervention length, but it is likely to include 3-6 sessions of CHW home visits based on formative work with ongoing supervision and support for CHWs.",[14],[25,28,31],{"name":26,"affiliation":5,"role":27},"Jessica F Magidson, PhD","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":27},"Tara Carney, PhD","Medical Research Council, South Africa",{"name":32,"affiliation":33,"role":27},"Bronwyn Myers, PhD","Curtin University; South African Medical Research Council",[35,39],{"name":26,"role":36,"phone":37,"phoneExt":12,"email":38},"CONTACT","301-405-5095","jmagidso@umd.edu",{"name":40,"role":36,"phone":12,"phoneExt":12,"email":41},"Abigail C Hines, MPH","ahines01@umd.edu",[43],{"facility":44,"status":12,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"South African Medical Research Council - Delft Office","Cape Town","Western Cape","7580","South Africa","ZA",{"type":51,"coordinates":52},"Point",[53,54],18.42322,-33.92584,{"lat":54,"lon":53},[57],{"name":58,"role":36,"phone":12,"phoneExt":12,"email":12},"Kim Johnson, MA",{"type":60,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[62,63,66],{"name":30,"class":6},{"name":64,"class":65},"Fogarty International Center of the National Institute of Health","NIH",{"name":67,"class":6},"Curtin University","100591839","khanya-ekhaya-a-home-based-intervention-100591839",false,"NCT06985641","Khanya Ekhaya: A Home-Based Intervention","Home-Based Community Health Worker Support for Mental Health Among People Living With HIV in South Africa: A Hybrid Effectiveness Implementation Trial","Inclusion Criteria:\n\n* at least 18 years old\n* must be a CHW who conducts home visits for people with HIV newly initiating or re-initiating ART at the approved clinic site\n\nExclusion Criteria:\n\n-Unable or unwilling to complete informed consent and study procedures in English, isiXhosa, or Afrikaans","ALL","18 Years",{"count":78,"type":79},119,"ESTIMATED","INTERVENTIONAL",[82],"NA","Mental health conditions, such as depression, anxiety, and harmful alcohol use are prevalent among people with chronic diseases, including HIV, and contribute to poor engagement in care. There is a need to address untreated mental health problems. Community health workers (CHWs) are frontline workers who play a central role in supporting vulnerable individuals to stay in care, including seeking people living with HIV who are newly initiating antiretroviral therapy (ART) or re-initiating after a period of care disengagement. CHW-delivered interventions are promising for improving engagement and retention in care. Yet, these programs rarely address mental health -a significant barrier to chronic disease care engagement and treatment. An approach that moves beyond providing care in the clinic setting is needed.\n\nCommunity-delivered mental health care shows promise for integration into broader community health care services for people with chronic conditions, such as HIV. However, as CHWs are taking on more mental health care roles and community-based work, our team's preliminary research has demonstrated that high levels of stress and burnout are important considerations for successful implementation of these models.",[85,86,87,88,89,90,91],"Mental Health","Community Health Workers","Training","Global Health","Burnout","Well-being","Natured-informed Therapy",[86,93,88,94,95,89,90,96],"Health Personnel","Health Care Seeking Behavior","Attitude of Health Personnel","Nature-informed therapy","NOT_YET_RECRUITING","2026-08-14",{"date":100,"type":101},"2026-08-18","ACTUAL",{"date":103,"type":79},"2026-08-17",{"date":105,"type":79},"2026-11-23",{"name":5,"class":6},1]