[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651475":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":23,"locations":33,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":78,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":9,"interventionNames":11},"Patients",null,[12],"Other: Value of neurofilament light chain (NFL) at different time points",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Value of neurofilament light chain (NFL) at different time points","Value of neurofilament light chain (NFL) at different time points (H0, H12, H24, H48, H72, H96, and day 7 after ICU admission",[9],[19],{"name":20,"affiliation":21,"role":22},"Sarah Benghanem","Medical ICU, Cochin hospital, Paris","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Sarah Benghanem, MD PhD","CONTACT","+ 00 33 1 58 41 43 3","sarah.benghanem@aphp.fr",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Marie Benhammani-Godard","0033158411190","marie.godard@aphp.fr",[34],{"facility":35,"status":10,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Medical ICU","Paris","IDF","75014","France","FR",{"type":42,"coordinates":43},"Point",[44,45],2.3488,48.85341,{"lat":45,"lon":44},[48],{"name":49,"role":26,"phone":50,"phoneExt":10,"email":28},"Sarah Benhganem","00331 58 41 43 35",{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100651475","kinetics-and-prognostic-value-of-neurofilament-light-in-post-cardiac-arrest-a-prospective-multicenter-study-100651475",false,"NCT07760636","Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study","CINEFIL","Inclusion Criteria:\n\n* Patients admitted to the ICU for cardiac arrest,\n* Patients who regained consciousness following in-hospital or out-of-hospital cardiac arrest,\n* Patients in a coma upon arrival in the ICU, defined by a Glasgow Coma Scale (GCS) score \\\u003C8,\n* Patients included in the AfterROSC2 cohort,\n\nExclusion Criteria:\n\n* Terminally ill patients (death expected within 3 hours of admission to the ICU),\n* Minors,\n* Patients under legal guardianship,\n* Pregnant women,\n* Patients not enrolled in a social security program,\n* Prior inclusion in the CINEFIL study,\n* Restriction of active therapies prior to the first NFL biomarker assay,\n* Objection by a family member or trusted person, if present","ALL","18 Years",{"count":63,"type":64},270,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to assess the prognostic value of absolute value and kinetic of neurofilament light chain (NFL) collected at different time points (at admission, 12h, 24h, 48h, 72h, 96h, and day 7 after ICU admission) in predicting poor and good neurological outcome in comatose patients after cardiac arrest.",[68,69,70,71],"Cardiac Arrest (CA)","Intensive Care Unit (ICU) Admission","Return of Spontaneous Circulation","Comatose",[73,74,75,76,77],"Cardiac arrest","Coma","Neuroprognostication","Biomarkers","Neurofilament light chain","NOT_YET_RECRUITING","2026-08-10",{"date":81,"type":82},"2026-08-12","ACTUAL",{"date":84,"type":64},"2026-09",{"date":86,"type":64},"2028-06",{"name":5,"class":6},1]