[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648883":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":37,"responsibleParty":52,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":83,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Ankara Etlik City Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"10 mmHg Pneumoperitoneum","ACTIVE_COMPARATOR","Participants assigned to this arm will undergo laparoscopic appendectomy using a pneumoperitoneum pressure of 10 mmHg throughout the procedure. Patients will be allocated using sealed opaque envelope randomization. All other perioperative management and surgical techniques will be standardized.",[13],"Procedure: Laparoscopic appendectomy with 10 mmHg pneumoperitoneum",{"label":15,"type":10,"description":16,"interventionNames":17},"15 mmHg Pneumoperitoneum","Participants assigned to this arm will undergo laparoscopic appendectomy using a pneumoperitoneum pressure of 15 mmHg throughout the procedure. Patients will be allocated using sealed opaque envelope randomization. All other perioperative management and surgical techniques will be standardized.",[18],"Procedure: Laparoscopic appendectomy with 15 mmHg pneumoperitoneum",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Laparoscopic appendectomy with 10 mmHg pneumoperitoneum","Laparoscopic appendectomy performed using an intra-abdominal pneumoperitoneum pressure of 10 mmHg.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Laparoscopic appendectomy with 15 mmHg pneumoperitoneum","Laparoscopic appendectomy performed using an intra-abdominal pneumoperitoneum pressure of 15 mmHg.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Yılmaz Türk, Operator Doctor","CONTACT","+905321349903","+90","yturk9@gmail.com",[38],{"facility":39,"status":25,"city":40,"state":41,"zip":42,"country":43,"countryCode":25,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Ankara Etlik Şehir Hastanesi","Ankara","Yenimahalle","06170","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],32.85427,39.91987,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":36},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Dr Yilmaz TURK","Operator Doctor","100648883","laparoscopic-appendectomy-outcomes-of-10-mmhg-versus-15-mmhg-intra-abdominal-pressure-100648883",false,"NCT07727499","Laparoscopic Appendectomy: Outcomes of 10 mmHg Versus 15 mmHg Intra-abdominal Pressure","Comparison of Standard Pneumoperitoneum Pressures in Laparoscopic Appendectomy: Clinical Outcomes of 10 mmHg Versus 15 mmHg Intra-abdominal Pressure","Inclusion Criteria:\n\n* Age 18-60 years.\n* Clinical and\u002For radiological diagnosis of acute appendicitis.\n* Planned laparoscopic appendectomy(Uncomplicated acute appendicitis considered suitable for laparoscopic management).\n* ASA physical status I-III.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years and \\>60 years\n* Pregnancy\n* Appendiceal mass or suspected appendiceal malignancy\n* Diffuse peritonitis requiring planned open surgery\n* Severe cardiopulmonary disease in whom pneumoperitoneum pressure cannot be standardized\n* Previous extensive abdominal surgery causing expected severe adhesions\n* Patients requiring additional major abdominal procedure\n* Missing consent\n* Incomplete postoperative follow-up\n* Patients managed non-operatively without surgery","ALL","18 Years","60 Years",{"count":67,"type":68},150,"ESTIMATED","INTERVENTIONAL",[71],"NA","This prospective, randomized controlled trial aims to compare the clinical outcomes of laparoscopic appendectomy performed under two standard pneumoperitoneum pressures (10 mmHg and 15 mmHg). The primary objective is to evaluate postoperative pain, while secondary outcomes include operative time, conversion rate, time to first flatus and bowel movement, length of hospital stay, postoperative ileus, and intra-abdominal abscess formation. The study will determine whether lower-pressure pneumoperitoneum provides comparable surgical conditions while improving postoperative recovery.",[74,75],"Appendectomy, Laparoscopic","Intra Abdominal Pressure",[77,78,79,80,81,82],"pain","vas","flatus","pressure","appendicitis","intra-abdominal pressure","NOT_YET_RECRUITING","2026-07-21",{"date":86,"type":87},"2026-07-27","ACTUAL",{"date":86,"type":68},{"date":90,"type":68},"2027-10-27",{"name":5,"class":6},1]