[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491177":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":41,"centralContacts":45,"locations":54,"responsibleParty":100,"collaborators":102,"id":106,"slug":107,"hasResults":108,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":40,"eligibilityCriteria":112,"healthyVolunteers":113,"sex":114,"minAge":115,"maxAge":40,"enrollmentInfo":116,"targetDuration":40,"studyType":119,"phases":120,"briefSummary":122,"conditions":123,"keywords":40,"overallStatus":57,"whyStopped":40,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":134},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8,14,18,22,26,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort 1","EXPERIMENTAL","6 of the 36 recruited opioid treatment programs (OTPs) will be enrolled in group 1. Group 1 will start the six-month intervention at Baseline and end at Month 6.",[13],"Behavioral: Clinic-Level Multidimensional Intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Cohort 2","6 of the 36 recruited opioid treatment programs (OTPs) will be enrolled in Cohort 2. Cohort 2 will start the six-month intervention at Month 6 and end at Month 12.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Cohort 3","6 of the 36 recruited opioid treatment programs (OTPs) will be enrolled in Cohort 3. Cohort 3 will start the six-month intervention at Month 12 and end at Month 18.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Cohort 4","6 of the 36 recruited opioid treatment programs (OTPs) will be enrolled in Cohort 4. Cohort 4 will start the six-month intervention at Month 18 and end at Month 24.",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Cohort 5","6 of the 36 recruited opioid treatment programs (OTPs) will be enrolled in Cohort 5. Cohort 5 will start the six-month intervention at Month 24 and end at Month 30.",[13],{"label":31,"type":10,"description":32,"interventionNames":33},"Cohort 6","6 of the 36 recruited opioid treatment programs (OTPs) will be enrolled in Cohort 5. Cohort 5 will start the six-month intervention at Month 30 and end at Month 36.",[13],[35],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"BEHAVIORAL","Clinic-Level Multidimensional Intervention","The proximal goal of the intervention will be to increase OTP uptake of flexible THD. The intervention addresses facilitators and barriers to THD practices as identified by existing studies as well as those found during the first phase of the current project. The intervention will be designed to address the information gaps, training needs, and beliefs of individuals across the organizations.",[9,15,19,23,27,31],null,[42],{"name":43,"affiliation":5,"role":44},"Charles Neighbors, PhD","PRINCIPAL_INVESTIGATOR",[46,50],{"name":43,"role":47,"phone":48,"phoneExt":40,"email":49},"CONTACT","646-501-3875","Charles.Neighbors@nyulangone.org",{"name":51,"role":47,"phone":52,"phoneExt":40,"email":53},"Beth Knopf, MPH","646-481-2528","Elizabeth.Knopf@nyulangone.org",[55,72,82,91],{"facility":56,"status":57,"city":58,"state":59,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"University of Connecticut","RECRUITING","Storrs","Connecticut","06268","United States","US",{"type":64,"coordinates":65},"Point",[66,67],-72.24952,41.80843,{"lat":67,"lon":66},[70],{"name":71,"role":44,"phone":40,"phoneExt":40,"email":40},"Megan O'Grady, Ph.D.",{"facility":73,"status":57,"city":74,"state":75,"zip":76,"country":61,"countryCode":62,"cosmosGeoPoint":77,"geoPoint":81,"contacts":40},"University at Buffalo","Buffalo","New York","14260",{"type":64,"coordinates":78},[79,80],-78.87837,42.88645,{"lat":80,"lon":79},{"facility":5,"status":57,"city":75,"state":75,"zip":83,"country":61,"countryCode":62,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"10016",{"type":64,"coordinates":85},[86,87],-74.00597,40.71427,{"lat":87,"lon":86},[90],{"name":43,"role":44,"phone":40,"phoneExt":40,"email":40},{"facility":92,"status":57,"city":75,"state":75,"zip":93,"country":61,"countryCode":62,"cosmosGeoPoint":94,"geoPoint":96,"contacts":97},"Weill Cornell Medical College","10065",{"type":64,"coordinates":95},[86,87],{"lat":87,"lon":86},[98],{"name":99,"role":44,"phone":40,"phoneExt":40,"email":40},"Yuhua Bao",{"type":101,"investigatorFullName":40,"investigatorTitle":40,"investigatorAffiliation":40,"oldNameTitle":40,"oldOrganization":40},"SPONSOR",[103],{"name":104,"class":105},"National Institutes of Health (NIH)","NIH","100491177","leveraging-regulatory-flexibility-for-methadone-take-home-dosing-to-improve-retention-in-treatment-for-opioid-use-disorder-100491177",false,"NCT05675735","Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder","Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder: A Stepped-Wedge Randomized Trial to Facilitate Clinic Level Changes","Inclusion Criteria:\n\n* Clinic staff inclusion will include anyone who works at the 10 clinics that the OASAS client data system generates from the quantitative analysis in year one. In years 2-5, clinics chosen by the OASAS client data system will be placed into six cohorts. Only staff from these clinics will be eligible.\n* Patient inclusion will include anyone aged 18 or older who has been receiving take-home methadone for at least 30 days.\n\nExclusion Criteria\n\n• There are no exclusion criteria related to sex\u002Fgender to increase the generalizability of the findings. The investigators will note include children in this study because the treatment system that we are examining largely excludes adolescents and younger children.",true,"ALL","18 Years",{"count":117,"type":118},318,"ESTIMATED","INTERVENTIONAL",[121],"NA","Using a stepped-wedge randomized controlled trial, the study will test whether a clinic-level multidimensional intervention conducted in 36 opioid treatment programs (OTPs) will improve clinical decision making, regulatory confusion, legal liability concerns, capacity for clinical practice change, and financial barriers to take- home dosing (THD) for methadone as compared to treatment as usual.",[124],"Problems Related to Social Environment","2026-08-10",{"date":127,"type":128},"2026-08-12","ACTUAL",{"date":130,"type":128},"2023-01-27",{"date":132,"type":118},"2027-08-31",{"name":5,"class":6},4]