[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646896":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":24,"locations":23,"responsibleParty":30,"collaborators":34,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":23,"enrollmentInfo":48,"targetDuration":23,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":59,"whyStopped":23,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":23},{"fullName":5,"class":6},"George Mason University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LifeBio Memory (LBM) digital reminiscence intervention","EXPERIMENTAL","Participants will access the LifeBio Memory (LBM) digital reminiscence platform using a mobile phone or tablet. Informal caregivers will complete a brief training. During Weeks 1-2, dyads will complete at least two weekly sessions recording the older adult's life stories using structured prompts. During Weeks 3-5, dyads will complete one weekly reminiscence and social engagement session. In Week 6, participants will receive personalized LifeBio story materials, including a Life Story Book, Snapshot, and story summary.",[13],"Other: LifeBio Memory (LBM) digital reminiscence intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Waitlist Control (Delayed LBM digital reminiscence intervention)","ACTIVE_COMPARATOR","Participants will receive general education on brain health and information about available local social services during the control period. After the control period, participants will participate in the LifeBio Memory (LBM) App intervention.",[13],[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"LifeBioMEMORY (LBM) is a multilingual digital reminiscence therapy platform that guides older adults through life story sharing using culturally relevant prompts, photos, and voice recording in Spanish, Korean, or English. The app includes \"My Story\" and \"Fun Things to Do\" features to support reminiscence and engagement while capturing personal narratives. Using machine learning, LBM generates personalized Life Story Books and summaries in the preferred language of the older adult and informal caregiver, with electronic and printed copies available. The intervention is designed to promote social engagement, strengthen caregiver relationships, and support person-centered care.",[9,15],null,[25],{"name":26,"role":27,"phone":28,"phoneExt":23,"email":29},"Kyeung Mi Oh, PhD","CONTACT","703 993 4550","koh5@gmu.edu",{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Kyeung Mi Oh","Principal Investigator",[35],{"name":36,"class":37},"National Institute on Aging (NIA)","NIH","100646896","lifebio-memory-development-of-a-reminiscence-therapy-online-platform-with-machine-learning-to-increase-engagement-100646896",false,"NCT07685067","LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement","LifeBio Memory","The investigators will enroll a total of 84 older adult participants and 84 informal caregivers across the 84 dyads, comprising 21 Hispanic\u002FLatino dyads, 21 Korean dyads, 21 Black dyads, and 21 Non-Hispanic White dyads.\n\nThe inclusion and exclusion criteria for older adult participants are:\n\n1. Self-identified as Hispanic\u002FLatino, Korean, Black\u002FAfrican American, and Non-Hispanic White\n2. Speak and read Spanish, Korean, or English\n3. Aged 60 years and older, with Montreal Cognitive Assessment (MoCA) test scores ranging 18-30 (with MCI: 18-25, or at risk for MCI: 26-30)\n4. Have a local or in-home informal caregiver who can participate who is age 18 or older\n5. No pre-existing acute psychotic disease or critical illness\n6. Consent to participate\n\nThe inclusion and exclusion criteria for informal caregivers are:\n\n1. Self-identified as Hispanic\u002FLatino, Korean, Black\u002FAfrican American, and Non-Hispanic White\n2. Speak and read Spanish, Korean, or English\n3. Aged 18 years and older\n4. Currently serving as the primary informal caregiver for older adults aged 60 or older\n5. No pre-existing acute psychotic disease or critical illness\n6. Consent to participate",true,"ALL","60 Years",{"count":49,"type":50},168,"ESTIMATED","INTERVENTIONAL",[53],"NA","LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being. This study will develop and evaluate an enhanced multilingual LBM app for community-dwelling, diverse older adults with mild cognitive impairment (MCI) or at risk of MCI and their informal caregivers, including Hispanic\u002FLatino, Asian American (as one of subgroups, Korean), Black or African American, and non-Hispanic White populations. The app provides culturally tailored life story prompts with audio and visual cues to encourage reminiscence and storytelling. The intervention aims to improve quality of life, reduce depressive symptoms and loneliness, and strengthen caregiver-care recipient relationships, with the potential to provide an accessible, non-pharmacological approach to supporting cognitive and emotional well-being.",[56],"Mild Cognitive Impairment",[56,58],"Reminiscence","NOT_YET_RECRUITING","2026-07-02",{"date":62,"type":63},"2026-07-06","ACTUAL",{"date":65,"type":50},"2026-08-01",{"date":67,"type":50},"2028-05-31",{"name":5,"class":6}]