[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646712":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":43,"centralContacts":47,"locations":57,"responsibleParty":93,"collaborators":96,"id":105,"slug":106,"hasResults":107,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":113,"sex":114,"minAge":115,"maxAge":116,"enrollmentInfo":117,"targetDuration":52,"studyType":120,"phases":121,"briefSummary":123,"conditions":124,"keywords":128,"overallStatus":60,"whyStopped":52,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":158},{"fullName":5,"class":6},"National University of Singapore","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"VIPP-SD-SingH","EXPERIMENTAL","Participants assigned to this arm will receive the VIPP-SD-SingH program. Both adult and child participants will actively take part in at least some aspects of the VIPP-SD-SingH.\n\nEach VIPP-SD-SingH session is scheduled as close to 14 days after the prior home-visit as possible. Participants will not progress to the next VIPP-SD-SingH session if they have not completed the prior one. However, the maximum duration for the intervention will be 32 weeks.",[13],"Behavioral: VIPP-SD-SingH, \"Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline Adapted for the Singapore Context with a Health Component\"",{"label":15,"type":6,"description":16,"interventionNames":17},"CARE-SD","Participants assigned to this arm will receive the CARE-SD program for proof of principle, implying whatever the outcome further tests are indispensable for translation to policy or practice. Results will further inform feasibility\u002Facceptability and preliminarily efficacy information.\n\nParents will be asked to watch online CARE-SD sessions and then involve children in activities. After session videos have been opened, participants can mark a session as complete. Then, the completed session's materials will remain accessible for 14 days. Marking a session \"complete\" also triggers the next session to open 14 days later. User metrics and additional self-reported involvement data (e.g., How much did you watch? Did you do the activities?) will be collected, but will not influence the first-level assessment of completion (for Intent to Treat analyses) or session progression. Participants will not progress without completing prior sessions, though the maximum duration will be 32 weeks.",[18],"Behavioral: CARE-SD, \"Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline\"",{"label":20,"type":6,"description":21,"interventionNames":22},"NeuroEducation for Parents","This arm will serve as an Active Control for both VIPP-SD-SingH and CARE-SD. It is not expected to notably impact sensitive caregiving though it may impact caregiver knowledge about child development.\n\nAfter a sessions' videos have been opened, participants will have access to a form where they can mark a session as complete. Once they do so, the completed session's materials will remain accessible for 14 days. Marking a session as \"complete\" also triggers the next session to open 14 days later. Although user metrics and additional self-reported involvement data (e.g., How much did you watch? Did you read the additional material?) will be collected, those will not influence the first-level assessment of completion (for Intent to Treat analyses) or session progression.\n\nPeople will not progress to the next NeuroEducation session if they have not completed the prior one. However, the maximum duration for the intervention will be 32 weeks.",[23],"Behavioral: NeuroEducation for Parents",[25,32,38],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","VIPP-SD-SingH, \"Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline Adapted for the Singapore Context with a Health Component\"","The VIPP-SD-SingH is an adaptation of the seven session home-visiting VIPP-SD program. During the first six VIPP-SD sessions the parent-child dyad will be asked to take part in certain activities together while being recorded. During sessions 2-7 the parent will watch the prior sessions's videos and receive frequent (e.g., 10-30 second) feedback ( e.g., focusing on children's perspectives, awareness of attachment and explorative child behavior, tips for sensitive discipline, and back-and-forth behavior). The VIPP-SD-SingH will include some adjustments for local language use and VIPP-SD compatible stimulation for reflections on tips and activities that allow greater generalization of the VIPP-SD principles to physical health contexts (e.g., waiting to eat a snack, using toys that encourage movement, or activities that may encourage relaxation).",[9],[31],"This was referred to as \"O\" or \"Own\" during earlier LOVING Development\u002FPilot research.",{"type":26,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"CARE-SD, \"Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline\"","CARE-SD, Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline was developed within the context of proof-of-concept research. CARE-SD is a standardized, digitally delivered parenting program using vicarious pre-rendered video examples and comments derived from the VIPP-SD program and does not include personalized feedback during home visits. Furthermore, CARE-SD includes health related scenarios and language and settings familiar to families living in Singapore. As with the VIPP-SD-SingH, CARE-SD's design includes seven sessions with scenarios and comments for generalizability to physical activity, feeding, and relaxation. After watching each of the videos in sessions 2-7, parents will be asked to try out the activities they've viewed with their own child. Instructions and suggestions for materials will be provided as will be questions for reflection.",[15],[37],"This was referred to as \"V\" or \"Vicarious\" in LOVING Developmental\u002FPilot research.",{"type":26,"name":20,"description":39,"armGroupLabels":40,"otherNames":41},"NeuroEducation for Parents was designed as a seven session online program for parents containing informational videos about young children's Brain Basics, Seven Senses, Learning and Memory, Emotion, Curiosity and Creativity, Thinking, and Friendships. Sensitive caregiving is not discussed explicitly. Each session will end with a short video quiz, complete with answers. Additional optional written material will be provided for parents who wish to learn more.",[20],[42],"This was referred to as \"E\" or \"neuroEducation\" in LOVING Developmental\u002FPilot research.",[44],{"name":45,"affiliation":5,"role":46},"Anne E Rifkin-Graboi, PhD","PRINCIPAL_INVESTIGATOR",[48,54],{"name":49,"role":50,"phone":51,"phoneExt":52,"email":53},"Christy Yifan Jiang, PhD","CONTACT","80695639",null,"jyifan@nus.edu.sg",{"name":55,"role":50,"phone":51,"phoneExt":52,"email":56},"Shamini Sanmugam, MA","shamini.sanmugam@nus.edu.sg",[58,70,75,81,87],{"facility":59,"status":60,"city":61,"state":61,"zip":62,"country":61,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":52},"Insitute of Human Development and Potential, Agency for Science and Technology Research (A*STAR)","RECRUITING","Singapore","117609","SG",{"type":65,"coordinates":66},"Point",[67,68],103.85007,1.28967,{"lat":68,"lon":67},{"facility":5,"status":60,"city":61,"state":61,"zip":71,"country":61,"countryCode":63,"cosmosGeoPoint":72,"geoPoint":74,"contacts":52},"11907",{"type":65,"coordinates":73},[67,68],{"lat":68,"lon":67},{"facility":76,"status":60,"city":61,"state":61,"zip":77,"country":61,"countryCode":63,"cosmosGeoPoint":78,"geoPoint":80,"contacts":52},"KK Women and Children's Hospital","229899",{"type":65,"coordinates":79},[67,68],{"lat":68,"lon":67},{"facility":82,"status":60,"city":61,"state":61,"zip":83,"country":61,"countryCode":63,"cosmosGeoPoint":84,"geoPoint":86,"contacts":52},"National Institute of Education, Nanyang Technological University","637616",{"type":65,"coordinates":85},[67,68],{"lat":68,"lon":67},{"facility":88,"status":60,"city":61,"state":61,"zip":89,"country":61,"countryCode":63,"cosmosGeoPoint":90,"geoPoint":92,"contacts":52},"Nanyang Technological University","639798",{"type":65,"coordinates":91},[67,68],{"lat":68,"lon":67},{"type":46,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":52,"oldOrganization":52},"Anne Rifkin-Graboi","Research Associate Professor",[97,98,100,102],{"name":88,"class":6},{"name":99,"class":6},"Institute for Human Development and Potential (IHDP), Singapore",{"name":101,"class":6},"National Institute of Education, Singapore",{"name":103,"class":104},"KK Women's and Children's Hospital","OTHER_GOV","100646712","loving-learning-about-our-behavior-is-valuable-for-increasing-nurturing-relationships-and-healthy-growth-rct-100646712",false,"NCT07687524","LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCT","LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth)","LOVING","Children must be 2 to 5.5 years of age at their pre-test visit. Children with a medical or developmental condition that makes it hard for them to see, hear, move, or communicate in typical ways (for example, autism spectrum disorder, down syndrome, spina bifida, or serious vision or hearing problems) will not be eligible to participate. This is because the study focuses on everyday patterns of parent-child interaction. Children with minor or symptom-free medical or genetic conditions (for example, traits that do not affect their day-to-day health or development) can take part.\n\nParents must be between 21 and 65 years old at the time of consent. Mothers and fathers who consider themselves to have a major caregiving role are eligible. Parents who have been hospitalized for more than two weeks (inclusive) within the past 6 months and\u002For have had any in-patient mental health treatment within the past 6 months may not participate, nor may parents with notable neurodegenerative diagnosis such as Alzheimer's, Parkinson's, or Huntington's disease.\n\nParticipants must be from families earning near to Singapore's median household income or below, provided recruitment and enrollment difficulties have not triggered a pre-defined rule leading to the omission of this requirement. Parents and children must be able to communicate in English, Mandarin, Bahasu Melayu, and\u002For Tamil. Participants must also be willing to be audio-video recorded and amenable to random assignment.",true,"ALL","2 Years","65 Years",{"count":118,"type":119},624,"ESTIMATED","INTERVENTIONAL",[122],"NA","The LOVING study is a randomized controlled trial designed to determine whether adaptations to an internationally recognized parenting program that enhances sensitive caregiving likewise improves sensitive caregiving in Singapore and, in turn, downstream child outcomes in emotional, behavioral, and cognitive development during the early childhood years.\n\nResearch shows that sensitive caregiving is linked to secure relationships, decreased child mental health problems, better executive functioning, and potentially healthier body mass indices. The Video Feedback to Improve Positive Parenting and Sensitive Discipline (VIPP-SD) program is an internationally recognized home-based intervention designed to enhance sensitive caregiving. However, evidence demonstrating its efficacy in Asia remains extremely limited. Moreover, most previous evaluations have focused primarily on parenting or child mental health outcomes, with newer work only beginning to focus upon additional child outcomes.\n\nIn this study, families with young children from median-income and below households living in Singapore will be randomly assigned to one of three groups. Some families will participate in a locally adapted version of the home-based VIPP-SD program that includes additional health-related scenarios (VIPP-SD-SingH). Other families will be assigned to CARE-SD, which was developed within the context of proof-of-concept research. CARE-SD is a standardized, digitally delivered parenting program using vicarious pre-rendered video examples and comments derived from the VIPP-SD program and does not include personalized feedback during home visits. Furthermore, CARE-SD includes health related scenarios and language and settings familiar to families living in Singapore. A third group will receive developmental information about children's learning and development (i.e., NeuroEducation Active Control). The programs are brief and are designed to be practical and accessible for families.\n\nFamilies participating in the study will take part in research visits that include questionnaires, observations of parent-child interaction, and activities designed to assess children's development. Laboratory visits will take place at IHDP (a collaborating institution) research facilities. Information collected in the study will help researchers better understand how parenting support programs influence children's emotional well-being, behavior, learning, and physical health.\n\nThe results of this research may help inform the development of effective programs to support families and promote healthy child development.",[125,126,127],"Child Development","Child Behavioral Problems","Parent Child Relationship",[129,130,131,132,133,134,9,15,135,136,137,138,139,140,141,142,143,144,145,146,147,148,61],"VIPP-SD","Sensitive caregiving","Executive function","BMI","Physical fitness","Externalizing problems","NeuroEducation","Asian","Cortisol","Genetic","Dopamine","EEG","Theta","Frontal Alpha Asymmetry","Emotional memory bias","Preschool","Vicarious","Home visiting","Digital","Sensitive Discipline","2026-07-01",{"date":151,"type":152},"2026-07-07","ACTUAL",{"date":154,"type":152},"2026-05-25",{"date":156,"type":119},"2028-02-09",{"name":5,"class":6},5]