[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647818":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":19,"locations":29,"responsibleParty":59,"collaborators":18,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":18,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":18,"enrollmentInfo":70,"targetDuration":18,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":32,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Abramson Cancer Center at Penn Medicine","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Single","Participants will complete study intervention which consists of the BPI-SF, PROMIS Global v1.2, UEFI (for those with joint pain of the upper extremity) and\u002For LEFS (for those joint pain of the lower extremity) at baseline, 3-month and 1-year follow-up following 1 or 2 courses of standard of care LDRT.",[12],"Radiation: Low Dose Radiation Therapy",[14],{"type":15,"name":16,"description":10,"armGroupLabels":17,"otherNames":18},"RADIATION","Low Dose Radiation Therapy",[9],null,[20,25],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},"Marlowe Estioko, BS, MS","CONTACT","267-343-6483","Marlowe.Estioko@Pennmedicine.upenn.edu",{"name":26,"role":22,"phone":27,"phoneExt":18,"email":28},"Sonya George, BS","267-760-7636","Sonya.George@PennMedicine.upenn.edu",[30,50],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Penn Presbyterian Medical Center","RECRUITING","Philadelphia","Pennsylvania","19104","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-75.16362,39.95238,{"lat":42,"lon":41},[45,46,47],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},{"name":26,"role":22,"phone":27,"phoneExt":18,"email":28},{"name":48,"role":49,"phone":18,"phoneExt":18,"email":18},"John Plastaras, MD, PhD","PRINCIPAL_INVESTIGATOR",{"facility":51,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":52,"geoPoint":54,"contacts":55},"Perelman Center for Advanced Medicine",{"type":39,"coordinates":53},[41,42],{"lat":42,"lon":41},[56,57,58],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},{"name":26,"role":22,"phone":27,"phoneExt":18,"email":28},{"name":48,"role":49,"phone":18,"phoneExt":18,"email":18},{"type":60,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100647818","low-dose-radiotherapy-for-osteoarthritis-100647818",false,"NCT07715188","Low Dose Radiotherapy for Osteoarthritis","A Prospective Study of Low Dose Radiotherapy for Osteoarthritis","Inclusion Criteria:\n\n* 18 years or older\n* Diagnosis of OA \\>3 months in hips, knees, hands, shoulders, ankles or elbows.\n* Refractory to standard of care therapies for OA or those who are being considered for more aggressive interventional treatment such as joint replacement, but more conservative treatment is desired.\n* Provision of signed and dated informed consent.\n\nExclusion Criteria:\n\n* Unable to reasonably complete study instruments.","ALL","18 Years",{"count":71,"type":72},113,"ESTIMATED","INTERVENTIONAL",[75],"NA","This single institution, multi-site, single arm prospective study will enroll patients with a history of OA and assess changes in pain and function after treatment with LDRT as measured by patient-reported outcomes.",[78],"Osteoarthitis",[80,81],"Low Dose Radiotherapy","Osteoarthritis","2026-07-15",{"date":84,"type":85},"2026-07-20","ACTUAL",{"date":87,"type":85},"2026-06-24",{"date":89,"type":72},"2029-06",{"name":5,"class":6},2]