[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651907":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":43,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Fatih Sultan Mehmet Training and Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Elective Lumbar Disc Herniation Surgery Cohort",null,"Adults aged 18 to 75 years with ASA physical status I-III who are scheduled for elective surgery for lumbar disc herniation under general anesthesia. Participants will receive routine perioperative care, and no intervention will be assigned by the study protocol. The exposures of interest are the preoperative psoas muscle index and multifidus muscle area and index measured using existing lumbar Magnetic Resonance Imaging (MRI) scans. QoR-15 scores will be recorded before surgery and at 24 hours, 48 hours, and 7 days after surgery. Postoperative pain, analgesic consumption, nausea and vomiting, recovery unit stay, time to first mobilization, and hospital stay will also be recorded.",[13],"Other: Preoperative Psoas and Multifidus Muscle Measurements",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Preoperative Psoas and Multifidus Muscle Measurements","Preoperative psoas muscle index and multifidus muscle cross-sectional area and index will be measured by manual segmentation of existing axial T2-weighted lumbar MRI images at the L3 inferior endplate level. No additional MRI examination or clinical intervention will be performed. These measurements represent observational exposures whose associations with postoperative QoR-15 scores and other recovery outcomes will be evaluated",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Doğa Meriç Yükselen, MD","CONTACT","+905362963155","d.m.boybeyi@gmail.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"cansu ofluoğlu, MD","+905358640564","cansuakin.iu@gmail.com",[30],{"facility":5,"status":10,"city":31,"state":10,"zip":32,"country":33,"countryCode":10,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Istanbul","34752","Turkey (Türkiye)",{"type":35,"coordinates":36},"Point",[37,38],28.94966,41.01384,{"lat":38,"lon":37},[41],{"name":42,"role":22,"phone":23,"phoneExt":10,"email":24},"doğa meriç Yükselen, MD",{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Doğa Meriç Yükselen","Specialist in Anesthesiology and Reanimation","100651907","lower-back-muscle-size-and-recovery-after-lumbar-disc-herniation-surgery-100651907",false,"NCT07768241","Lower Back Muscle Size and Recovery After Lumbar Disc Herniation Surgery","Association of Preoperative Psoas Muscle Index and Multifidus Muscle Area With Postoperative Quality of Recovery Assessed Using the Quality of Recovery-15 (QoR-15) in Patients Undergoing Surgery for Lumbar Disc Herniation: A Prospective Observational Study","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* Scheduled for elective surgery for lumbar disc herniation\n* American Society of Anesthesiologists physical status I-III\n* Availability of a preoperative lumbar MRI obtained as part of routine clinical care\n* Scheduled to undergo surgery under general anesthesia\n* Sufficient cognitive and communication ability to understand and complete the quality of recovery (QoR-15) questionnaire\n* Willingness to participate and provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Revision lumbar spine surgery\n* Surgery for a spinal tumor, infection, trauma, vertebral fracture, spinal deformity, advanced spinal stenosis, or another condition other than lumbar disc herniation\n* Planned spinal fusion or instrumentation\n* History of a neuromuscular disorder\n* Severe cognitive impairment, inability to communicate, or inability to complete the QoR-15 questionnaire\n* Chronic opioid use or a history of opioid dependence\n* Preoperative lumbar MRI images of insufficient quality for psoas or multifidus muscle measurement","ALL","18 Years","75 Years",{"count":58,"type":59},100,"ESTIMATED","OBSERVATIONAL","Recovery after surgery for a herniated disc in the lower back differs from person to person. The size of the muscles around the lower spine may be related to recovery, but this relationship is not well understood.\n\nThe purpose of this observational study is to determine whether the size of two lower-back muscles, the psoas and multifidus muscles, measured on magnetic resonance imaging (MRI) scans obtained before surgery is related to recovery after surgery. The study will include 100 adults aged 18 to 75 years who are scheduled for elective surgery for lumbar disc herniation.\n\nParticipants will receive their usual anesthesia, surgery, and postoperative care. The study will not require any additional imaging, blood tests, medicines, or procedures. Researchers will use each participant's existing preoperative lumbar MRI scan to measure the psoas and multifidus muscles. Participants will complete the 15-item Quality of Recovery questionnaire (QoR-15) before surgery and again 24 hours, 48 hours, and 7 days after surgery. Researchers will also collect information routinely recorded during care, including pain scores, pain medicine use, nausea and vomiting, time spent in the recovery unit, time to first walking, and length of hospital stay.\n\nThe primary objective is to determine whether preoperative psoas muscle index and multifidus muscle cross-sectional area are independently associated with postoperative Quality of Recovery-15 (QoR-15) scores 24 hours after lumbar disc herniation surgery.",[63,64],"Postoperative Recovery","Lumbar Disc Herniation",[66,67,68,69,70,71,72,73],"Psoas Muscle Index","Multifidus Muscle Area","Paraspinal Muscle Morphology","Quality of Recovery-15","Lumbar Magnetic Resonance Imaging","Lumbar Spine Surgery","Patient-Reported Outcome","Postoperative Pain","NOT_YET_RECRUITING","2026-08-13",{"date":77,"type":78},"2026-08-17","ACTUAL",{"date":80,"type":59},"2026-09",{"date":82,"type":59},"2027-07",{"name":5,"class":6},1]