[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656932":3},{"organization":4,"outcomesModule":7,"designInfo":42,"detailedDescription":49,"studyPopulation":41,"armGroups":50,"interventions":64,"overallOfficials":41,"centralContacts":79,"locations":83,"responsibleParty":103,"collaborators":105,"id":109,"slug":110,"hasResults":111,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":41,"eligibilityCriteria":115,"healthyVolunteers":111,"sex":116,"minAge":117,"maxAge":41,"enrollmentInfo":118,"targetDuration":41,"studyType":121,"phases":122,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":85,"whyStopped":41,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":141},{"fullName":5,"class":6},"Taipei Medical University Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":41},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Skeletal Muscle Mass Index (SMI)","Skeletal muscle mass index (SMI) will be measured in kg\u002Fm². Lower values indicate lower skeletal muscle mass. According to the criteria used in this study, low muscle mass is defined as SMI ≤7.0 kg\u002Fm² in men and ≤5.7 kg\u002Fm² in women.","Baseline, Week 5, and Week 8",{"measure":14,"description":15,"timeFrame":12},"Handgrip Strength","Handgrip strength of the dominant hand will be measured in kilograms (kg). Higher values indicate greater muscle strength. According to the criteria used in this study, low muscle strength is defined as \\\u003C28 kg in men and \\\u003C18 kg in women.",{"measure":17,"description":18,"timeFrame":12},"4-Meter Gait Speed","Gait speed will be assessed using the 4-meter walk test and reported in meters per second (m\u002Fs). Higher values indicate better walking performance. According to the criteria used in this study, a gait speed \\\u003C1.0 m\u002Fs indicates impaired physical performance.",[20,23,26,29,32,35,38],{"measure":21,"description":22,"timeFrame":12},"Five-Time Sit-to-Stand Test","The time required to complete five consecutive sit-to-stand movements will be recorded in seconds. A shorter completion time indicates better lower-limb functional performance.",{"measure":24,"description":25,"timeFrame":12},"Functional Ambulation Category","Walking ability will be assessed using the Functional Ambulation Category (FAC).",{"measure":27,"description":28,"timeFrame":12},"Short Physical Performance Battery","Physical performance and balance will be assessed using the Short Physical Performance Battery (SPPB).",{"measure":30,"description":31,"timeFrame":12},"EQ-5D Health-Related Quality of Life","Health-related quality of life will be assessed using the EQ-5D questionnaire.",{"measure":33,"description":34,"timeFrame":12},"Lower Extremity Functional Scale (LEFS)","Self-reported lower-extremity function will be assessed using the Lower Extremity Functional Scale (LEFS).",{"measure":36,"description":37,"timeFrame":12},"Sarcopenia Health Literacy","Participants' knowledge and health literacy related to sarcopenia will be assessed using a sarcopenia health literacy questionnaire.",{"measure":39,"description":40,"timeFrame":12},"Sarcopenia-Specific Quality of Life","Sarcopenia-specific quality of life will be assessed using the Traditional Chinese short-form sarcopenia quality-of-life questionnaire.",null,{"allocation":43,"interventionModel":44,"interventionModelDescription":45,"primaryPurpose":46,"observationalModel":41,"timePerspective":41,"maskingInfo":47},"NON_RANDOMIZED","PARALLEL","Two-arm, parallel, non-randomized quasi-experimental study comparing lower-limb rehabilitation robot training plus nutrition education with usual care including exercise and nutrition education.","TREATMENT",{"masking":48,"maskingDescription":41,"whoMasked":41},"NONE","Sarcopenia is associated with loss of muscle mass, reduced muscle strength, impaired physical function, and increased risks of falls and disability in older adults. Conventional exercise and nutritional interventions often require longer treatment periods to achieve measurable improvements. Lower-limb rehabilitation robots may provide intensive and repetitive gait training over a shorter period, while nutrition education may support maintenance or improvement of muscle health.\n\nThis study uses a two-arm, parallel, quasi-experimental design to evaluate the additional effects of lower-limb rehabilitation robot training when added to nutrition education and usual care in adults with sarcopenia. Participants in both groups will undergo assessments at baseline, mid-intervention, and post-intervention. The study is intended to determine whether this combined approach can provide clinically meaningful improvements in muscle-related and functional outcomes and to assess its feasibility for clinical rehabilitation practice.",[51,58],{"label":52,"type":53,"description":54,"interventionNames":55},"Robot-Assisted Training Group","EXPERIMENTAL","Participants will receive lower-limb rehabilitation robot training using the MRG-P110 for 8 weeks, three sessions per week, 30 minutes per session, for a total of 24 sessions. Nutrition education will be provided after each training session.",[56,57],"Device: Lower-Limb Rehabilitation Robot Training","Behavioral: Nutrition Education",{"label":59,"type":60,"description":61,"interventionNames":62},"Usual Care Group","ACTIVE_COMPARATOR","Participants will receive usual care, including exercise and nutrition education, without additional lower-limb rehabilitation robot training.",[63],"Behavioral: Usual Care Exercise",[65,70,75],{"type":66,"name":67,"description":68,"armGroupLabels":69,"otherNames":41},"DEVICE","Lower-Limb Rehabilitation Robot Training","Participants will receive lower-limb rehabilitation robot training using the MRG-P110 for 8 weeks, three sessions per week, 30 minutes per session, for a total of 24 sessions. Training parameters will be individualized according to participant height and baseline walking speed. Step length will initially be set at 15% of height, and walking speed at 80% of baseline walking speed. Training intensity will be monitored using the Borg Rating of Perceived Exertion scale and maintained at 5-6.",[52],{"type":71,"name":72,"description":73,"armGroupLabels":74,"otherNames":41},"BEHAVIORAL","Nutrition Education","Participants will receive nutrition education as part of the study intervention.",[52],{"type":71,"name":76,"description":77,"armGroupLabels":78,"otherNames":41},"Usual Care Exercise","Participants in the control group will receive usual care exercise without additional lower-limb rehabilitation robot training.",[59],[80],{"name":81,"role":82,"phone":41,"phoneExt":41,"email":41},"SHENG-WEN SU","CONTACT",[84],{"facility":5,"status":85,"city":86,"state":87,"zip":88,"country":89,"countryCode":90,"cosmosGeoPoint":91,"geoPoint":96,"contacts":97},"RECRUITING","Taipei","Taipei City","11031","Taiwan","TW",{"type":92,"coordinates":93},"Point",[94,95],121.52639,25.05306,{"lat":95,"lon":94},[98],{"name":99,"role":82,"phone":100,"phoneExt":101,"email":102},"Sheng-Wen Su, PhD","+886-2-2874-3415","3244","10154susw@gmail.com",{"type":104,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[106],{"name":107,"class":108},"HIWIN Technologies Corporation","UNKNOWN","100656932","lower-limb-rehabilitation-robot-training-for-sarcopenia-100656932",false,"NCT07830472","Lower-Limb Rehabilitation Robot Training for Sarcopenia","Research on Lower Limb Rehabilitation Robots for Sarcopenia","Inclusion Criteria:\n\n* Aged 60 years or older.\n* Meets the diagnostic criteria for sarcopenia according to the Asian Working Group for Sarcopenia (AWGS).\n* Conscious and able to understand and follow movement instructions.\n* Able to stand for at least 1 minute.\n* Physically able to tolerate lower-limb rehabilitation robot training.\n\nExclusion Criteria:\n\n* Body weight greater than 135 kg.\n* Height less than 145 cm or greater than 190 cm, resulting in incompatibility with the exoskeleton.\n* Presence of an unhealed fracture.\n* Joint contracture or excessive lower-limb muscle tone that prevents participation in robotic training.","ALL","60 Years",{"count":119,"type":120},40,"ESTIMATED","INTERVENTIONAL",[123],"NA","The goal of this clinical trial is to learn whether lower-limb rehabilitation robot training combined with nutrition education can improve muscle mass and physical function in adults aged 60 years or older with sarcopenia. The main questions it aims to answer are:\n\n1. Does lower-limb rehabilitation robot training improve muscle mass and body composition?\n2. Does the training improve muscle strength, walking ability, balance, and physical function?\n\nResearchers will compare participants who receive lower-limb rehabilitation robot training plus nutrition education with participants who receive usual care, including exercise and nutrition education, to see whether adding robot-assisted training provides additional benefits.\n\nParticipants will:\n\n1. Complete assessments before the intervention, around week 5, and after week 8.\n2. Receive either 8 weeks of lower-limb rehabilitation robot training using the MRG-P110 plus nutrition education, or usual care including exercise and nutrition education.\n3. Complete assessments of body composition, muscle strength, walking ability, balance, and health-related quality of life.",[126],"Sarcopenia",[128,129,72,130,131],"Robot-Assisted Rehabilitation","High-Intensity Training","Physical Function","Walking Ability","2026-09-15",{"date":134,"type":135},"2026-09-21","ACTUAL",{"date":137,"type":135},"2026-03-09",{"date":139,"type":120},"2027-01",{"name":5,"class":6},1]