[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652140":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":50,"centralContacts":58,"locations":65,"responsibleParty":66,"collaborators":69,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":65,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":65,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":93,"overallStatus":100,"whyStopped":65,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":65},{"fullName":5,"class":6},"En Chu Kong Hospital","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Proprioceptive Training + Sham + LLLT","EXPERIMENTAL","Participants in this group will receive proprioceptive training combined with low-level laser acupuncture. For the first 2 weeks, sham laser acupuncture (identical visual and auditory cues with no energy output) will be administered, followed by 2 weeks of active laser acupuncture. Proprioceptive training will be performed three times daily throughout the 4-week period.",[13,14],"Device: Low-Level Laser Acupuncture","Behavioral: Proprioceptive Training",{"label":16,"type":10,"description":17,"interventionNames":18},"Proprioceptive Training + LLLT + LLLT","Participants in this group will receive proprioceptive training combined with 4 weeks of active low-level laser acupuncture. Proprioceptive training will be performed three times daily, and active laser acupuncture will be administered once weekly for the entire 4-week period.",[13,14],{"label":20,"type":21,"description":22,"interventionNames":23},"Waiting List Control","ACTIVE_COMPARATOR","Participants assigned to this group will serve as a waiting list control and will receive standard conservative care, specifically utilizing a stabilization splint, during the 4-week trial period. They will not receive the experimental proprioceptive training or laser acupuncture protocols during this phase.",[24],"Device: Stabilization Splint Treatment",[26,34,44],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DEVICE","Low-Level Laser Acupuncture","Laser acupuncture targets the Xiaguan (ST7), Yifeng (SJ17), and bilateral Fengchi (GB20) points once weekly. For the LLLT+LLLT group, active laser is given for 4 weeks. For the Sham+LLLT group, sham laser is given for the first 2 weeks followed by 2 weeks of active laser.",[16,9],[32,33],"Low-Level Laser","Laser Acupuncture",{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"BEHAVIORAL","Proprioceptive Training","Includes gentle teeth tapping, tongue-to-palate contact, and neutral head-neck posture exercises, performed three times daily for 4 weeks.",[16,9],[40,41,42,43],"Motor Control Training","Cranio-Cervico-Mandibular Malalignment \u002F Dysfunction Training","Sensorimotor Training","Trigemino-Cervical System Rehabilitation",{"type":27,"name":45,"description":46,"armGroupLabels":47,"otherNames":48},"Stabilization Splint Treatment","Standard conservative clinical care utilizing a hard acrylic flat-plane stabilization splint (centric stabilization splint) for TMD management. The splint is customized to provide even, bilateral occlusal contact in the musculoskeletal stable position during the 4-week trial period.",[20],[49],"occlusal splint",[51,55],{"name":52,"affiliation":53,"role":54},"Ching-Po Lin, PhD","Institute of Neuroscience, Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan. Department of Education and Research, Taipei City Hospital, Taipei, Taiwan.","STUDY_DIRECTOR",{"name":56,"affiliation":57,"role":54},"Ching-Mao Chang, MD, PhD","Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. Institute of Traditional Medicine, and Schools of Chinese Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.",[59],{"name":60,"role":61,"phone":62,"phoneExt":63,"email":64},"Ting-Yu Huang, D.D.S.","CONTACT","+886 2-2672-3456","6835","tingyuh3012@gmail.com",null,{"type":67,"investigatorFullName":60,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":65,"oldOrganization":65},"PRINCIPAL_INVESTIGATOR","Attending Physician, Department of Oral and Maxillofacial Surgery",[70],{"name":71,"class":6},"National Yang Ming Chiao Tung University","100652140","machine-learning-for-evaluating-and-diagnosing-temporomandibular-disorders-100652140",false,"NCT07771296","Machine Learning for Evaluating and Diagnosing Temporomandibular Disorders","Development of an Integrated Evaluation-to-Treatment Framework to Enhance Clinical Efficiency and Effectiveness in Temporomandibular Disorders","Inclusion Criteria:\n\n* Patients diagnosed with temporomandibular disorders (TMDs) screened by the Department of Dentistry, Division of Oral and Maxillofacial Surgery at En Chu Kong Hospital, who have failed to respond to analgesic treatment for at least one week.\n* Patients clinically examined and identified as having pain predominantly originating from muscles associated with mandibular movement.\n* Patients aged between 18 and 70 years (inclusive) with full legal capacity.\n* Patients who are willing to participate in the study and provide written informed consent.\n\nExclusion Criteria:\n\n* Patients meeting any of the following clinical scale thresholds: Generalized Anxiety Disorder-7 (GAD-7)≥ 10, Patient Health Questionnaire-9 (PHQ-9) ≥ 15, Patient Health Questionnaire-15 (PHQ-15) ≥ 10, or Pittsburgh Sleep Quality Index (PSQI) \\> 5.\n* Patients with tumors of the temporomandibular joint (TMJ) or head and neck region.\n* Patients with acute or chronic infections.\n* Patients with a history of neuropathy or stroke.\n* Patients with a history of head and neck trauma.\n* Patients diagnosed with fibromyalgia.\n* Patients diagnosed with autoimmune or rheumatic diseases.\n* Patients diagnosed with irritable bowel syndrome (IBS).\n* Patients with claustrophobia (unable to undergo MRI examination).\n* Women who are pregnant or lactating, or parents currently in the infant care\u002Fnursing period.\n* Patients who have received invasive treatment for temporomandibular joint disorders within the past 3 months.","ALL","18 Years","70 Years",{"count":83,"type":84},180,"ESTIMATED","INTERVENTIONAL",[87],"NA","This study aims to improve clinical efficiency and effectiveness in treating Temporomandibular Disorders (TMD). The researchers will integrate machine learning technology with clinical examination data, CBCT, and MRI to identify the core underlying issues of each patient. Based on this precise, AI-assisted diagnosis, the study will implement a tailored treatment framework. The final goal is to develop predictive algorithms that can determine MRI necessity while ensuring that clinical interventions are highly targeted, efficient, and successful.",[90,91,92],"Temporomandibular Disorders (TMD)","TMJ Disorder","TMJ Pain",[94,95,96,97,98,36,99,33],"Machine Learning","Cone-Beam Computed Tomography","CBCT","Magnetic Resonance Imaging","MRI","low level laser","NOT_YET_RECRUITING","2026-08-18",{"date":103,"type":104},"2026-08-20","ACTUAL",{"date":106,"type":84},"2026-10-05",{"date":108,"type":84},"2027-07-31",{"name":5,"class":6}]