[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650297":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":43,"locations":49,"responsibleParty":65,"collaborators":30,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":30,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":30,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":30,"overallStatus":51,"whyStopped":30,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Mayo Clinic-Approved Education","ACTIVE_COMPARATOR","The control group will receive standard of care, Mayo Clinic approved education for a duration of 60 minutes, every 2 weeks for 6 sessions (12 weeks)",[13],"Behavioral: Mayo Clinic-Approved Education",{"label":15,"type":16,"description":17,"interventionNames":18},"Digital Neuropathy","EXPERIMENTAL","The Digital Neuropathy group will utilize the web-based system (REJUVENATE) for a duration of 20 minutes, 4 times per week (12 weeks)",[19],"Behavioral: Digital Neuropathy",{"label":21,"type":16,"description":22,"interventionNames":23},"Capacity Coaching","The Capacity Coaching group will participate in calls with a board certified health and wellness coach for a duration of 60 minutes, every 2 weeks, for 6 sessions (12 weeks)",[24],"Behavioral: Capacity Coaching",[26,31,36],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Education attention control will be administered by board certified health and wellness coaches via virtual coaching sessions.",[9],null,{"type":27,"name":15,"description":32,"armGroupLabels":33,"otherNames":34},"The web-based system (REJUVENATE) consists of a set of cognitive exercises continuously and automatically adjusted in difficulty based on each user's performance to maintain the balance of challenge and success optimal to promote neuroplastic enhancement of target neural systems.",[15],[35],"REJUVENATE",{"type":27,"name":21,"description":37,"armGroupLabels":38,"otherNames":30},"Board certified health and wellness coaches will create a plan with subjects to use capacity, defined as patients' abilities and resources, to do self-management work.",[21],[40],{"name":41,"affiliation":5,"role":42},"Neera Dahl, MD, PhD","PRINCIPAL_INVESTIGATOR",[44],{"name":45,"role":46,"phone":47,"phoneExt":30,"email":48},"Ryan Helland, CCRP","CONTACT","507-422-3998","RSTTEMPORESGROUP@mayo.edu",[50],{"facility":5,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-92.4699,44.02163,{"lat":61,"lon":60},[64],{"name":45,"role":46,"phone":47,"phoneExt":30,"email":30},{"type":42,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Neera Dahl","Principal Investigator","100650297","managing-depressive-symptoms-in-adpkd-100650297",false,"NCT07745920","Managing Depressive Symptoms in ADPKD","A Pilot Study for Managing Depressive Symptoms in Autosomal Dominant Polycystic Kidney Disease (ADPKD)","Inclusion criteria:\n\n* Confirmed clinical diagnosis of ADPKD using Pei-Ravine criteria\n* Pre-End Stage Kidney Disease, with Stage 1-5 CKD (eGFR \\>10 ml\u002Fmin\u002F1.73m2, with no anticipated dialysis or transplant within 12 months)\n* Clinical or self-diagnosis of depression\n* English-language fluency\n\nExclusion criteria:\n\n* Suicidal ideation\u002Funstable mental illness of any kind\n* Lack of access\u002Fability to use internet-based programs\n* eGFR \\\u003C10 ml\u002Fmin\u002F1.73m2\n* Anticipated dialysis or transplant within 6 months\n* Prior chronic dialysis\n* Prior organ (liver or kidney) transplant\n* Lack of English language fluency\n* Significant cognitive impairment (Mini Mental Status Exam (MMSE))","ALL","18 Years","70 Years",{"count":79,"type":80},105,"ESTIMATED","INTERVENTIONAL",[83],"NA","The purpose of this research is to evaluate the feasibility and effectiveness of Digital Neurotherapy (DNT) or Capacity Coaching (CC) for managing symptoms of depression and self reported pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) compared to education alone.",[86],"Autosomal Dominant Polycystic Kidney Disease","2026-08-04",{"date":89,"type":90},"2026-08-07","ACTUAL",{"date":92,"type":90},"2026-06-12",{"date":94,"type":80},"2027-07-12",{"name":5,"class":6},1]