[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648690":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":45,"responsibleParty":61,"collaborators":43,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":43,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":43,"enrollmentInfo":72,"targetDuration":43,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":84,"whyStopped":43,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"mantram repetition program","EXPERIMENTAL","8-session group-based meditation training class led by a trained instructor",[13],"Behavioral: Mantram Repetition Program for PTSD + Pain",{"label":15,"type":16,"description":17,"interventionNames":18},"health education","ACTIVE_COMPARATOR","8-session group-based health education and discussion led by a trained instructor",[19],"Behavioral: Health Education while Living with Pain",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Mantram Repetition Program for PTSD + Pain","manualized Mantram Repetition Program adapted for Veterans with PTSD and chronic pain",[9],[27],"MRP",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Health Education while Living with Pain","manualized health and wellness psychoeducation and discussion group",[15],[33],"H.E.L.P.",[35],{"name":36,"affiliation":37,"role":38},"Anne L Malaktaris","VA San Diego Healthcare System, San Diego, CA","PRINCIPAL_INVESTIGATOR",[40],{"name":36,"role":41,"phone":42,"phoneExt":43,"email":44},"CONTACT","(858) 642-3794",null,"anne.malaktaris@va.gov",[46],{"facility":37,"status":43,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"San Diego","California","92161-0002","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-117.16472,32.71571,{"lat":56,"lon":55},[59,60],{"name":36,"role":41,"phone":42,"phoneExt":43,"email":44},{"name":36,"role":38,"phone":43,"phoneExt":43,"email":43},{"type":62,"investigatorFullName":43,"investigatorTitle":43,"investigatorAffiliation":43,"oldNameTitle":43,"oldOrganization":43},"SPONSOR","100648690","mantram-repetition-versus-health-education-for-veterans-with-ptsd-and-chronic-pain-100648690",false,"NCT07725588","Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain","Randomized Controlled Trial of Mantram Repetition Program Versus Health and Wellness Psychoeducation for Veterans With Comorbid Posttraumatic Stress Disorder and Chronic Pain","Inclusion Criteria:\n\n* U.S. Veteran\n* Diagnosis of PTSD\n* Chronic, non-malignant pain:\n\n  * (a) pain most days (\\> 3 days\u002Fweek) for at least 6 months\n  * (b) average pain severity and interference with enjoyment of life and\u002For general\n* Willing\u002Fable to engage in study activities\n\nExclusion Criteria:\n\n* Significant current risk of suicide or homicide\n* Untreated severe alcohol or substance use disorder\n* Untreated\u002Funstable serious mental health disorders, such as psychotic disorders, bipolar disorder, or serious dissociative symptoms\n* Impaired mental status\n* Concurrent interventions specifically targeting PTSD or CP or social functioning (e.g., couples therapy) or any meditative or mind-body intervention","ALL","18 Years",{"count":73,"type":74},170,"ESTIMATED","INTERVENTIONAL",[77],"NA","Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that efficiently target both PTSD and CP are limited, and new interventions should address the unique needs of Veterans with PTSD\u002FCP. Mantram Repetition Program (MRP), a meditation-based program, appears well-suited to address these high-priority VA needs. MRP has established effectiveness for treatment of PTSD, is broadly acceptable, can be learned quickly and applied flexibly. However, rigorous testing is needed for pain-related outcomes among a PTSD\u002FCP population. The proposed study will include a randomized controlled trial comparing the efficacy of MRP for PTSD\u002FCP to Health Education while Living with Pain among a sample of 170 Veterans with comorbid PTSD\u002FCP. The primary outcomes will be PTSD symptoms and pain interference. Results from this study will directly inform patient care among the nearly 4% of Veterans with PTSD\u002FCP.",[80,81],"Stress Disorders, Post-Traumatic","Pain, Chronic",[83],"Meditation","NOT_YET_RECRUITING","2026-07-24",{"date":87,"type":88},"2026-07-27","ACTUAL",{"date":90,"type":74},"2027-04-01",{"date":92,"type":74},"2030-09-30",{"name":5,"class":6},1]