[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650714":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":30,"centralContacts":38,"locations":44,"responsibleParty":63,"collaborators":30,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":30,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":47,"whyStopped":30,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Pontificia Universidad Catolica de Chile","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Mediterranean Diet","EXPERIMENTAL","Participants will receive individualized nutritional counseling to follow a Mediterranean diet, emphasizing fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, while limiting red meat and ultra-processed foods.",[13],"Behavioral: Mediterranean Diet",{"label":15,"type":10,"description":16,"interventionNames":17},"Mediterranean Diet + Time-Restricted Feeding","Participants will follow a Mediterranean diet combined with time-restricted feeding (16:8), consisting of an 8-hour eating window and a 16-hour fasting period",[18],"Behavioral: Mediterranean Diet + Time-Restricted Feeding",{"label":20,"type":21,"description":22,"interventionNames":23},"Standard Diet","ACTIVE_COMPARATOR","Participants will receive standard dietary counseling based on current clinical guidelines for ulcerative colitis.",[24],"Behavioral: Standard Dietary Advice",[26,31,34],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Participants will receive individualized nutritional counseling to follow a Mediterranean diet, emphasizing high intake of fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, and reduced consumption of red meat and ultra-processed foods. Dietary plans will be tailored to individual energy requirements.",[9],null,{"type":27,"name":15,"description":32,"armGroupLabels":33,"otherNames":30},"Participants will follow a time-restricted feeding protocol (16:8), consisting of a daily 16-hour fasting period and an 8-hour eating window (12:00-20:00). During the eating window, participants will consume meals based on Mediterranean diet guidelines, with individualized dietary counseling to ensure adequate nutritional intake.",[15],{"type":27,"name":35,"description":36,"armGroupLabels":37,"otherNames":30},"Standard Dietary Advice","Participants will receive standard dietary counseling based on current clinical guidelines for ulcerative colitis. This includes general recommendations for a balanced diet without specific emphasis on Mediterranean dietary patterns or time-restricted feeding.",[20],[39],{"name":40,"role":41,"phone":42,"phoneExt":30,"email":43},"Alejandra Parada Daza, Phd","CONTACT","+56994751585","acparada@uc.cl",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":30,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Pontificia Universidad Católica de Chile","RECRUITING","Santiago","Santiago Metropolitan","Chile","CL",{"type":53,"coordinates":54},"Point",[55,56],-70.64827,-33.45694,{"lat":56,"lon":55},[59],{"name":60,"role":41,"phone":61,"phoneExt":30,"email":62},"María Balcells, MD","+56955048170","proyectos.didemuc@uc.cl",{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Alejandra Parada Daza","Principal Investigator, Nutritionist, PhD, MSc, Department of Nutrition and Dietetics, School of Health Sciences, Pontificia Universidad Católica de Chile","100650714","mediterranean-diet-and-time-restricted-feeding-in-ulcerative-colitis-remission-100650714",false,"NCT07752446","Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission","Mediterranean Diet and Time-Restricted Feeding Intervention to Improve Gut Health, Quality of Life and Inflammation in Patients With Ulcerative Colitis in Remission: A Pilot Randomized Controlled Trial","MEDITIME-UC","Inclusion Criteria:\n\n* Adults aged 18 to 60 years\n* Diagnosis of ulcerative colitis\n* Clinical remission for at least 6 months\n* Fecal calprotectin \\\u003C 250 µg\u002Fg in the last 3 months\n* Daily eating window ≥ 11 hours\n\nExclusion Criteria:\n\n* Active ulcerative colitis\n* History of gastrointestinal surgery\n* Liver or kidney disease\n* Pregnancy\n* Eating disorders\n* Use of supplements (protein, antioxidants, probiotics)\n* Current restrictive diets (vegetarian, vegan, gluten-free, low-FODMAP)\n* High levels of physical activity","ALL","18 Years","60 Years",{"count":79,"type":80},45,"ESTIMATED","INTERVENTIONAL",[83],"NA","This study will evaluate whether a 12-week dietary intervention can improve gut health, inflammation, and quality of life in adults with ulcerative colitis in remission.\n\nParticipants will be randomly assigned to one of three groups: a Mediterranean diet, a Mediterranean diet combined with time-restricted feeding (eating within an 8-hour window each day), or standard dietary advice. The Mediterranean diet emphasizes fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, while limiting processed foods and red meat.\n\nThe main outcome will be changes in short-chain fatty acids in stool samples, which are markers of gut health. Additional outcomes include changes in inflammation markers, gastrointestinal symptoms, and quality of life.\n\nThe results of this study may help identify effective dietary strategies to support patients with ulcerative colitis.",[86,87],"Ulcerative Colitis (Disorder)","Inflammatory Bowel Disease (IBD)",[9,89,90,91,92,93],"Short-Chain Fatty Acids","Dietary Intervention","Time-Restricted Feeding","Ulcerative Colitis","Inflammation","2026-08-03",{"date":96,"type":97},"2026-08-07","ACTUAL",{"date":99,"type":97},"2026-04-10",{"date":101,"type":80},"2027-06-01",{"name":5,"class":6},1]