[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658346":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":18,"studyPopulation":22,"armGroups":23,"interventions":18,"overallOfficials":18,"centralContacts":33,"locations":39,"responsibleParty":53,"collaborators":18,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":18,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":18,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":18,"briefSummary":71,"conditions":72,"keywords":18,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Nigde Omer Halisdemir University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Pain Intensity Assessed Using the Visual Analog Scale","Pain intensity will be assessed using the 100-mm Visual Analog Scale (VAS), ranging from 0 to 100 mm, with higher scores indicating greater pain intensity. Pain scores will be compared among participants in the follicular phase, luteal phase, and postmenopausal groups.","-Before treatment(baseline) -Immediately after local anesthetic injection -Immediately after completion of endodontic treatment -Postoperative Day 1 -Postoperative Day 2",[14],{"measure":15,"description":16,"timeFrame":17},"Dental Anxiety Assessed Using the Modified Dental Anxiety Scale","Dental anxiety will be assessed using the 5-item Modified Dental Anxiety Scale (MDAS), with total scores ranging from 5 to 25. Higher scores indicate greater dental anxiety. Scores will be evaluated among participants in the follicular phase, luteal phase, and postmenopausal groups.","Before endodontic treatment",null,{"allocation":18,"interventionModel":18,"interventionModelDescription":18,"primaryPurpose":18,"observationalModel":20,"timePerspective":21,"maskingInfo":18},"COHORT","PROSPECTIVE","Women aged 18 years or older who present to the Department of Endodontics, Faculty of Dentistry, Nigde Omer Halisdemir University and require root canal treatment. Eligible participants who voluntarily agree to participate will be included and classified according to menstrual cycle phase (follicular or luteal phase) or postmenopausal status.",[24,27,30],{"label":25,"type":18,"description":26,"interventionNames":18},"Follicular Phase Group","Women undergoing routine endodontic treatment who are in the follicular phase of their menstrual cycle.",{"label":28,"type":18,"description":29,"interventionNames":18},"Luteal Phase Group","Women undergoing routine endodontic treatment who are in the luteal phase of their menstrual cycle.",{"label":31,"type":18,"description":32,"interventionNames":18},"Postmenopausal Group","Postmenopausal women undergoing routine endodontic treatment.",[34],{"name":35,"role":36,"phone":37,"phoneExt":18,"email":38},"Zübeyde Gökçe Ürün, Assistant Professor","CONTACT","+905378880030","gurun@ohu.edu.tr",[40],{"facility":41,"status":42,"city":43,"state":18,"zip":18,"country":44,"countryCode":18,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Niğde Omer Halisdemir University","RECRUITING","Niğde","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],34.67935,37.96583,{"lat":49,"lon":48},[52],{"name":35,"role":36,"phone":37,"phoneExt":18,"email":38},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Zübeyde Gökçe ÜRÜN","Assistant Professor","100658346","menstrual-cycle-menopause-and-pain-perception-during-endodontic-treatment-100658346",false,"NCT07850167","Menstrual Cycle, Menopause, and Pain Perception During Endodontic Treatment","Effects of Menstrual Cycle Phases and Menopause on Pain Perception in Endodontic Therapy","Inclusion Criteria:\n\n* Willing to participate in the study\n* Aged 18 years or older\n* Having at least one tooth requiring root canal treatment\n\nExclusion Criteria:\n\n* Aged under 18 years\n* No tooth requiring root canal treatment\n* Male sex\n* Diagnosis of endometriosis or polycystic ovary syndrome (PCOS)\n* Use of oral contraceptives\n* Receiving hormone therapy",true,"FEMALE","18 Years",{"count":68,"type":69},130,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate whether menstrual cycle phases and menopausal status are associated with pain perception in patients undergoing endodontic treatment. The main questions it aims to answer are:\n\nDoes pain experienced during endodontic treatment differ according to the phase of the menstrual cycle? Is pain perception during endodontic treatment different between premenopausal and postmenopausal women? Are menstrual cycle phases and menopausal status associated with pain experienced after endodontic treatment?\n\nParticipants undergoing endodontic treatment as part of their routine dental care will provide information about their menstrual cycle or menopausal status. Pain will be assessed at different stages of treatment and during the follow-up period after treatment. No treatment will be assigned based on menstrual cycle phase or menopausal status.",[73,74,75],"Pain Perception in Endodontic Treatment","Menstrual Cycle","Menopause","2026-09-29",{"date":78,"type":79},"2026-09-30","ACTUAL",{"date":81,"type":79},"2026-03-10",{"date":83,"type":69},"2027-03",{"name":5,"class":6},1]