[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647711":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":28,"locations":10,"responsibleParty":35,"collaborators":37,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":68,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":10},{"fullName":5,"class":6},"Tam Anh Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MIS Group",null,"Participants with spontaneous deep intracerebral hemorrhage who receive standard medical treatment according to current clinical practice guidelines. Clinical and safety outcomes will be assessed through 180 days of follow-up.",[13],"Procedure: Minimally Invasive Surgery (MIS)",{"label":15,"type":10,"description":11,"interventionNames":16},"Standard Medical Treatment Group",[17],"Other: Standard medical treatment (SMT)",[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Minimally Invasive Surgery (MIS)","Patients with spontaneous deep intracerebral hemorrhage who undergo minimally invasive surgery as part of routine clinical care. Decisions regarding surgical treatment and timing are made by the treating physicians according to standard practice. Clinical outcomes and safety outcomes will be evaluated through 180 days of follow-up.",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Standard medical treatment (SMT)","Participants receive standard medical management according to current clinical practice guidelines for spontaneous intracerebral hemorrhage. Treatment decisions are made by the treating physicians. Clinical and safety outcomes will be evaluated through 180 days of follow-up.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Huy Tan Chu, MD-PhD","CONTACT","+842839976276","1668","huyct@tamri.vn",{"type":36,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[38,40],{"name":39,"class":6},"Tam Anh TP. Ho Chi Minh General Hospital",{"name":41,"class":42},"People's Hospital 115","UNKNOWN","100647711","minimally-invasive-surgery-for-spontaneous-deep-intracerebral-hemorrhage-100647711",false,"NCT07710313","Minimally Invasive Surgery for Spontaneous Deep Intracerebral Hemorrhage","Effectiveness and Safety of Minimally Invasive Surgery for Spontaneous Deep Intracerebral Hemorrhage: A Prospective and Retrospective Observational Cohort Study","MIS-DEEP ICH","Inclusion Criteria:\n\n* Age 18 to 80 years\n* Spontaneous basal ganglia intracerebral hemorrhage confirmed by non-contrast CT\n* Hematoma volume between 30 and 80 mL (calculated using the ABC\u002F2 method)\n* Time from symptom onset to enrollment ≤ 72 hours (for patients with an unknown onset time, the last known well time will be used)\n* Glasgow Coma Scale (GCS) score between 5 and 14\n* Pre-stroke modified Rankin Scale (mRS) score of 0 to 1\n\nExclusion Criteria:\n\n* Secondary intracerebral hemorrhage due to trauma, brain tumor, arteriovenous malformation, cerebral aneurysm, or hemorrhagic transformation of ischemic stroke\n* Infratentorial hemorrhage involving the brainstem or cerebellum\n* Primary thalamic hemorrhage\n* Intraventricular extension occupying more than 50% of either lateral ventricle\n* NIHSS score \\\u003C 5\n* Bilaterally fixed and dilated pupils with no light reflexes\n* Decerebrate posturing\n* Platelet count \\\u003C 75,000\u002FμL\n* IINR \\> 1.4 after correction\n* Ongoing anticoagulation that cannot be rapidly reversed\n* Indication for long-term anticoagulation within 5 days of symptom onset\n* End-stage renal disease\n* End-stage liver disease\n* Presence of a mechanical heart valve\n* Comorbid condition associated with a life expectancy \\\u003C 6 months\n* Inability or unwillingness of the participant or legally authorized representative to provide written informed consent","ALL","18 Years","80 Years",{"count":55,"type":56},300,"ESTIMATED","OBSERVATIONAL","This observational cohort study evaluates the real-world effectiveness and safety of minimally invasive surgery (MIS) versus standard medical management in adults with spontaneous deep intracerebral hemorrhage. Patients presenting to Tam Anh General Hospital and People's Hospital 115 within 72 hours of hemorrhage onset will be enrolled and followed for 180 days. Clinical, radiological, and treatment-related variables will be collected, with primary outcome measures including survival and functional outcomes during follow-up period.",[60,61,62],"Intracerebral Hemorrhage","Spontaneous Intracerebral Hemorrhage","Basal Ganglia Hemorrhage",[61,64,62,65,66,67],"Deep Intracerebral Hemorrhage","Minimally Invasive Surgery","Robotic-Assisted Surgery","Hematoma Evacuation","NOT_YET_RECRUITING","2026-07-15",{"date":71,"type":72},"2026-07-17","ACTUAL",{"date":74,"type":56},"2026-07-01",{"date":76,"type":56},"2028-12-31",{"name":5,"class":6}]