[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100653347":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":20,"studyPopulation":13,"armGroups":21,"interventions":28,"overallOfficials":13,"centralContacts":34,"locations":40,"responsibleParty":59,"collaborators":61,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":13,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":13,"studyType":77,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":43,"whyStopped":13,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Tang-Du Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Regional Gray Matter Volume Across MRI Field Strengths","Regional gray matter volumes will be quantified from standardized structural MRI data and compared across 0.55T, 1.5T, 3T, 5T, and 7T MRI acquisitions.","From enrollment through completion of all scheduled multi-field-strength MRI examinations, up to 12 months",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"NA","SINGLE_GROUP","BASIC_SCIENCE",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE","This is a prospective multi-field-strength neuroimaging study involving healthy Chinese adults. Eligible participants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T according to the study protocol.\n\nMRI acquisitions include structural imaging, diffusion imaging, functional imaging, and quantitative imaging sequences where applicable. Images will undergo standardized preprocessing, registration, segmentation, and quantitative analysis. Multi-field-strength brain templates will be constructed, and anatomical and functional imaging characteristics will be compared across magnetic field strengths.\n\nThe study aims to establish normative multi-field-strength MRI reference data and brain atlases for healthy Chinese adults and to evaluate the consistency and field-strength-related differences in brain morphometry, cortical measurements, diffusion characteristics, functional connectivity, and other quantitative MRI parameters.",[22],{"label":23,"type":24,"description":25,"interventionNames":26},"Healthy Chinese Adults","EXPERIMENTAL","Healthy Chinese adult volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths according to the study protocol.",[27],"Diagnostic Test: Multi-Field-Strength Brain MRI",[29],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":13},"DIAGNOSTIC_TEST","Multi-Field-Strength Brain MRI","Participants will undergo standardized brain MRI examinations at 0.55T, 1.5T, 3T, 5T, and 7T. MRI acquisitions include structural, diffusion, functional, and quantitative imaging sequences according to the study protocol. No therapeutic intervention will be administered",[23],[35],{"name":36,"role":37,"phone":38,"phoneExt":13,"email":39},"Ziheng Zhou","CONTACT","+86 18710574531","173416171@qq.com",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":13,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Tangdu Hospital, Fourth Military Medical University","RECRUITING","Xi'an","Shaanxi","China","CN",{"type":49,"coordinates":50},"Point",[51,52],108.92861,34.25833,{"lat":52,"lon":51},[55],{"name":56,"role":37,"phone":57,"phoneExt":13,"email":58},"Shicao Li","029-84717761","tangduec@126.com",{"type":60,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR",[62],{"name":63,"class":6},"Xi'an Jiaotong University","100653347","multi-field-strength-mri-brain-atlas-construction-in-healthy-chinese-population-100653347",false,"NCT07786233","Multi-Field-Strength MRI Brain Atlas Construction in Healthy Chinese Population","Inclusion Criteria:\n\n* Aged 16 to 66 years. Voluntarily participates in the study and provides written informed consent. No contraindications to MRI examination and able to cooperate with and complete the MRI examinations.\n\nFemale participants must not be pregnant. No current or previous clinical diagnosis of severe neurological or psychiatric disorders, such as schizophrenia, dementia, epilepsy, or severe sequelae of traumatic brain injury.\n\nNo obvious intracranial lesions or structural abnormalities identified on routine MRI examination.\n\nExclusion Criteria:\n\n* Presence of contraindications to MRI examination, including MRI-incompatible implanted metallic or electronic devices, cochlear implants, cardiac pacemakers, intracranial metallic clips, or similar devices.\n\nSevere claustrophobia preventing completion of the MRI examination. Pregnancy. Current or previous clinical diagnosis of severe neurological or psychiatric disorders.\n\nHistory of severe head trauma, brain tumor, stroke, brain surgery, or other conditions that may substantially affect brain structure or function.\n\nMRI data of insufficient quality for analysis due to marked discomfort, excessive head motion, or other causes during the examination.",true,"ALL","16 Years","66 Years",{"count":75,"type":76},500,"ESTIMATED","INTERVENTIONAL",[15],"This prospective imaging study aims to construct a multi-field-strength magnetic resonance imaging (MRI) brain atlas for healthy Chinese adults. Healthy volunteers will undergo standardized brain MRI examinations at multiple magnetic field strengths, including 0.55T, 1.5T, 3T, 5T, and 7T. Structural, diffusion, functional, and other quantitative MRI data will be acquired and analyzed. The study will characterize the consistency and differences in brain morphology and imaging measurements across field strengths and establish standardized multi-field-strength brain templates and reference data for healthy Chinese adults.",[81],"Healthy Adult Brain Imaging",[23,83,84,85],"Brain Atlas","Magnetic Resonance Imaging","Multi-Field-Strength MRI","2026-08-21",{"date":88,"type":89},"2026-08-25","ACTUAL",{"date":91,"type":89},"2026-07-01",{"date":93,"type":76},"2028-02-01",{"name":5,"class":6},1]