[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657902":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":21,"studyPopulation":13,"armGroups":22,"interventions":29,"overallOfficials":35,"centralContacts":39,"locations":49,"responsibleParty":68,"collaborators":13,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":13,"enrollmentInfo":79,"targetDuration":13,"studyType":82,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":52,"whyStopped":13,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"sensitivity and specificity of pseudo-CT MRI","To evaluate the sensitivity and specificity of pseudo-CT MRI for the detection of bone lesions.","One MRI of 30 min",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":18,"observationalModel":13,"timePerspective":13,"maskingInfo":19},"NA","SINGLE_GROUP","All patients will undergo the same procedure: a CT scan scheduled for their clinical follow-up, supplemented by an MRI performed for the purposes of the study.","DIAGNOSTIC",{"masking":20,"maskingDescription":13,"whoMasked":13},"NONE","Magnetic resonance imaging (MRI) is the gold-standard modality for examining the bone marrow and soft tissues of the spine, thanks to its excellent contrast resolution. It enables precise visualization of the intervertebral discs, nerve roots, and spinal cord. However, its ability to visualize bone mineral remains limited due to the rapid decay of the T2 signal and the inability of conventional sequences to capture signals from tissues with very short relaxation times. Consequently, assessing bone structures-such as cortical or trabecular bone, osteophytes, or fractures-remains challenging, particularly in cases of complex pathologies.\n\nInnovative sequences known as \"pseudo-CT\" sequences-such as Ultrashort Echo Time (UTE) and Zero Echo Time (ZTE)-enable the capture of signals from tissues with very short T2 relaxation times and provide good visualization of mineralized bone. These new sequences appear to enhance MRI performance in the detection of fractures, spondylolysis, and other bone abnormalities.\n\nDespite the promising potential of \"pseudo-CT\" sequences, studies comparing them to conventional CT and MRI sequences remain limited, as do data regarding their overall clinical benefit. Further research is therefore needed to evaluate their diagnostic value, their ability to improve patient management, and their potential to reduce the need for other imaging examinations.",[23],{"label":24,"type":25,"description":26,"interventionNames":27},"All patients","EXPERIMENTAL","Each patient has a lumbar spine CT scan scheduled as part of their clinical follow-up. We are adding a lumbar spine MRI for the purposes of the study.",[28],"Device: MRI",[30],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":13},"DEVICE","MRI","Lumbar spine MRI using innovative sequences known as \"pseudo-CT,\" enabling the capture of signals from tissues with very short T2 relaxation times and providing good visualization of mineralized bone.",[24],[36],{"name":37,"affiliation":5,"role":38},"Frédéric E Lecouvet, MD-PhD","PRINCIPAL_INVESTIGATOR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":13,"email":44},"Frédéric Emmanuel Lecouvet, MD-PhD","CONTACT","003227642793","frederic.lecouvet@saintluc.uclouvain.be",{"name":46,"role":42,"phone":47,"phoneExt":13,"email":48},"Perrine Elizabeth Triqueneaux, Msc","003227642935","perrine.triqueneaux@saintluc.uclouvain.be",[50],{"facility":51,"status":52,"city":53,"state":13,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Cliniques Universitaires Saint Luc","RECRUITING","Brussels","1200","Belgium","BE",{"type":58,"coordinates":59},"Point",[60,61],4.34878,50.85045,{"lat":61,"lon":60},[64,66],{"name":37,"role":42,"phone":43,"phoneExt":13,"email":65},"frederic.lecouvet@saintluc.ucouvain.be",{"name":67,"role":42,"phone":13,"phoneExt":47,"email":48},"Perrine E Triqueneaux, Msc",{"type":69,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100657902","multicentre-evaluation-of-spinal-bone-pathologies-using-zero-echo-time-zte-pseudo-ct-mri-sequences-a-clinical-implementation-study-100657902",false,"NCT07844577","Multicentre Evaluation of Spinal Bone Pathologies Using Zero Echo Time (ZTE) Pseudo-CT MRI Sequences: a Clinical Implementation Study","MULTILUMBAR","Inclusion Criteria:\n\n* Adults requiring a CT scan as part of their clinical assessment for lumbar spine imaging who also provide informed consent to participate in the study.\n* Patients presenting with acute or chronic low back pain and requiring a CT scan for diagnostic purposes.\n\nExclusion Criteria:\n\n* Contraindications to MRI, such as pacemakers, metal implants, severe claustrophobia, or pregnancy\n* Spinal surgery within the last six months.\n* Patients who cannot or do not wish to provide informed consent.","ALL","18 Years",{"count":80,"type":81},100,"ESTIMATED","INTERVENTIONAL",[15],"Innovative sequences known as \"pseudo-CT\"-such as Ultrashort Echo Time (UTE) and Zero Echo Time (ZTE)-enable good visualization of mineralized bone. These new sequences appear to enhance MRI performance in the detection of fractures, spondylolysis, and other bone abnormalities.\n\nWe would like to offer patients referred for a CT scan due to lumbar spine bone pathology the option of undergoing an MRI study, in order to compare the performance of the two techniques.",[86],"Lumbar Spine Pathology",[88,32,89],"CT","Pseudo CT MRI sequences","2026-09-21",{"date":92,"type":93},"2026-09-28","ACTUAL",{"date":95,"type":93},"2026-04-15",{"date":97,"type":81},"2027-03-30",{"name":5,"class":6},1]