[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647330":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":22,"centralContacts":27,"locations":35,"responsibleParty":51,"collaborators":11,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":11,"enrollmentInfo":64,"targetDuration":11,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Fundacion Miguel Servet","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":11},"No exercise during hospitalization","NO_INTERVENTION",null,{"label":13,"type":14,"description":15,"interventionNames":16},"Exercise during hospitalization","EXPERIMENTAL","Multicomponent individualized exercise intervention As mentioned earlier, patients in the control group (G0) will receive the usual care currently provided to other patients, which includes a referral to physical therapy if needed. The intervention for the multicomponent physical exercise intervention group (G1) will consist of a multicomponent physical training program that includes progressive and supervised aerobic endurance, strength, and balance training lasting 4-7 days during their hospitalization. This will be supervised by the research team from the Geriatrics Unit. Additionally, after hospital discharge, they will receive individualized guidelines to engage in multicomponent physical exercise for 3 months, along with individualized recommendations from the Nutrition and Dietetics Service of HUN. The multicomponent physical training program will consist of chair squat exercises. The main part of the training will utilize machines for strength training for the lower extremit",[17],"Other: Behavioral: Exercise",[19],{"type":6,"name":20,"description":15,"armGroupLabels":21,"otherNames":11},"Behavioral: Exercise",[13],[23],{"name":24,"affiliation":25,"role":26},"Nicolas Martinez-Velilla","Navarrabiomed-Fundación Miguel Servet-Hospital de Navarra","PRINCIPAL_INVESTIGATOR",[28,32],{"name":24,"role":29,"phone":30,"phoneExt":11,"email":31},"CONTACT","+34 848422287","nicolas.martinez.velilla@navarra.es",{"name":33,"role":29,"phone":30,"phoneExt":11,"email":34},"Fabricio Zambom-Ferraresi","fabricio.zambom.ferraresi@navarra.es",[36],{"facility":37,"status":38,"city":39,"state":11,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Hospital Universitario de Navarra","RECRUITING","Pamplona","31008","Spain","ES",{"type":44,"coordinates":45},"Point",[46,47],-1.64323,42.81687,{"lat":47,"lon":46},[50],{"name":24,"role":29,"phone":30,"phoneExt":11,"email":31},{"type":52,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100647330","multicomponent-exercise-to-prevent-hospitalization-associated-disability-100647330",false,"NCT07707310","Multicomponent Exercise to Prevent Hospitalization-Associated Disability","Prevention of Disability in Older Adults: From the Patient to the Molecule - A Randomized Controlled Trial (RCT)","FIS_Prevention","Inclusion Criteria:\n\n* Age equal to or greater than 75 years, admitted to the acute care unit for medical conditions.\n\nExclusion Criteria:\n\n* Explicit refusal expressed verbally or refusal to sign the informed consent by the patient\u002Fmain caregiver\u002Flegal guardian or inability to obtain it.\n* Life expectancy of less than 3 months or terminal oncological or non -oncological disease.\n* Inability to follow up.\n* Inability to participate in a multicomponent exercise program.\n* Medical contraindication to exercise.\n* Major neurocognitive disorder at moderate to severe stage (GDS - Fast Reisberg 5-7).\n* Moderate to severe disability (measured by the Barthel Index (BI \\\u003C60)). Expected hospital stay of less than 6 days.",true,"ALL","75 Years",{"count":65,"type":66},300,"ESTIMATED","INTERVENTIONAL",[69],"NA","The study is a randomized controlled trial conducted in the Geriatrics Department of a tertiary hospital in Spain (Hospital Universitario de Navarra). Participants aged 75 years or older will be recruited within the first 48 hours of admission to the acute care ward. Eligible hospitalized patients will be randomly assigned to either the intervention or control group using permuted block randomization (block sizes of 8 and 10), with consideration of gender balance.\n\nData will be collected at four time points: baseline assessment, hospital discharge, 1 month, and 3 months post-discharge.\n\nInclusion criteria include age ≥75 years and admission to the acute care unit. Exclusion criteria include refusal or inability to provide informed consent, life expectancy \\\u003C3 months or terminal illness (oncological or non-oncological), inability to complete follow-up, medical contraindications to exercise, severe neurocognitive impairment (GDS-FAST stage 7), or severe disability (Barthel Index \\\u003C35).",[72],"Clinical Deterioration",[74,75,76,77],"hospital acquired disability","exercise","function","cognition","2026-07-15",{"date":80,"type":81},"2026-07-16","ACTUAL",{"date":83,"type":81},"2025-02-01",{"date":85,"type":66},"2027-12-01",{"name":5,"class":6},1]