[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651711":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":10,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":39,"eligibilityCriteria":40,"healthyVolunteers":35,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":47,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":10,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},{"fullName":5,"class":6},"Shanghai Mental Health Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"GAD Cohort",null,"Participants diagnosed with generalized anxiety disorder (GAD) who receive routine clinical care. No specific treatment or intervention is assigned by the study protocol. Participants will be followed longitudinally, and information on clinical symptoms, treatments, blood samples, and multimodal neurophysiological and neuroimaging measures will be collected according to the study schedule.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Lanying LIU","CONTACT","13516816012","balindaliu@126.com",[19],{"facility":5,"status":10,"city":20,"state":10,"zip":10,"country":21,"countryCode":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":29},"Shanghai","China","CN",{"type":24,"coordinates":25},"Point",[26,27],121.45806,31.22222,{"lat":27,"lon":26},[30],{"name":14,"role":15,"phone":10,"phoneExt":10,"email":17},{"type":32,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100651711","multimodal-cohort-study-of-generalized-anxiety-disorder-100651711",false,"NCT07764211","Multimodal Cohort Study of Generalized Anxiety Disorder","A Cohort Study of Generalized Anxiety Disorder Based on Multimodal Data","MC-GAD","Inclusion Criteria:\n\nMeets the ICD-10 diagnostic criteria for generalized anxiety disorder (GAD). Aged 18 to 65 years. Hamilton Anxiety Rating Scale (HAMA) total score \\>14. Has at least a junior high school education and is able to complete self-report questionnaires.\n\nVoluntarily agrees to participate in the study and provides written informed consent.\n\nExclusion Criteria:\n\nMeets ICD-10 diagnostic criteria for any psychiatric disorder other than GAD, as assessed using the Mini International Neuropsychiatric Interview (M.I.N.I.).\n\nHas significant suicidal ideation or is considered to be at high risk of suicide.\n\nHas a clinically significant medical condition or clinically significant laboratory abnormalities.","ALL","18 Years","65 Years",{"count":45,"type":46},400,"ESTIMATED","1 Year","OBSERVATIONAL","Generalized anxiety disorder (GAD) is a common mental health condition characterized by persistent and excessive worry that is difficult to control. It can affect sleep, daily functioning, work, and quality of life. Some individuals experience long-lasting or recurrent symptoms, but the factors that influence the course and outcome of GAD are still not fully understood.\n\nThe main purpose of this study is to establish a long-term cohort of people with GAD and to better understand how their symptoms and health change over time. The study will also explore factors that may help predict symptom improvement, recurrence, and treatment outcomes.\n\nApproximately 400 adults with GAD who receive care at Shanghai Mental Health Center will participate in this study. Participants will undergo regular clinical assessments and follow-up visits.\n\nDuring the study, researchers will collect information about participants' symptoms, medical and treatment history, blood samples, and brain-related measurements. Participants will be followed at several time points to observe changes in symptoms and health. The information collected will be used to better understand the course of GAD and to support the development of more individualized approaches to diagnosis, treatment, and long-term care.",[51],"Generalized Anxiety Disorder (GAD)","NOT_YET_RECRUITING","2026-08-09",{"date":55,"type":56},"2026-08-13","ACTUAL",{"date":58,"type":46},"2026-08-01",{"date":60,"type":46},"2030-12-31",{"name":5,"class":6},1]