[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657684":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":30,"studyPopulation":31,"armGroups":32,"interventions":26,"overallOfficials":36,"centralContacts":46,"locations":52,"responsibleParty":65,"collaborators":26,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":26,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":26,"maxAge":26,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":26,"briefSummary":81,"conditions":82,"keywords":26,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Atılım University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":26},[9],{"measure":10,"description":11,"timeFrame":12},"Caregiver Burden (Zarit Burden Interview)","Caregiver burden will be assessed using the Zarit Burden Interview (ZBI). Higher scores indicate greater perceived caregiver burden.","Baseline",[14,17,20,23],{"measure":15,"description":16,"timeFrame":12},"Sleep Quality (Pittsburgh Sleep Quality Index)","Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). Total scores range from 0 to 21, with higher scores indicating poorer sleep quality. Scores above 5 indicate poor sleep quality.",{"measure":18,"description":19,"timeFrame":12},"Physical Activity (IPAQ-SF)","Physical activity will be assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). Total physical activity will be expressed as metabolic equivalent of task minutes per week (MET-min\u002Fweek) based on activities performed during the previous seven days. Total MET-min\u002Fweek is calculated as the sum of walking (3.3 METs × minutes × days), moderate-intensity activity (4.0 METs × minutes × days), and vigorous-intensity activity (8.0 METs × minutes × days). The minimum possible value is 0 MET-min\u002Fweek; there is no fixed maximum score. Higher MET-min\u002Fweek values indicate a higher level of physical activity and therefore a better outcome.",{"measure":21,"description":22,"timeFrame":12},"Body Awareness (Body Awareness Questionnaire)","Body awareness will be assessed using the 18-item Body Awareness Questionnaire (BAQ). Each item is rated on a 7-point Likert scale from 1 to 7, yielding a total score ranging from 18 to 126. Higher scores indicate greater body awareness and therefore a better outcome",{"measure":24,"description":25,"timeFrame":12},"Perceived Stress (Perceived Stress Scale)","Perceived stress will be assessed using the 10-item Perceived Stress Scale (PSS-10). Total scores range from 0 to 40, with higher scores indicating greater perceived stress.",null,{"allocation":26,"interventionModel":26,"interventionModelDescription":26,"primaryPurpose":26,"observationalModel":28,"timePerspective":29,"maskingInfo":26},"COHORT","PROSPECTIVE","This cross-sectional observational study aims to investigate the associations between multiple sclerosis (MS) severity and caregivers' sleep quality, physical activity, body awareness, perceived stress, and caregiver burden.\n\nA total of 68 caregivers of individuals with MS will be included. Disease severity will be assessed using the Expanded Disability Status Scale (EDSS). Caregiver outcomes will be evaluated using the Pittsburgh Sleep Quality Index (PSQI), International Physical Activity Questionnaire-Short Form (IPAQ-SF), Body Awareness Questionnaire (BAQ), Perceived Stress Scale (PSS), and Zarit Burden Interview (ZBI).\n\nThe study will examine the relationships between MS severity and caregiver health outcomes within the framework of the International Classification of Functioning, Disability and Health (ICF). No therapeutic intervention will be administered.","The study population will consist of 68 adult caregivers of individuals diagnosed with multiple sclerosis who receive care at Başkent University Hospital. Caregivers will be recruited to evaluate the associations between MS severity and caregiver health outcomes.",[33],{"label":34,"type":26,"description":35,"interventionNames":26},"Caregivers of Patients With Multiple Sclerosis","Adult caregivers who have provided regular care to a person diagnosed with multiple sclerosis for at least six months.",[37,41,43],{"name":38,"affiliation":39,"role":40},"Büşra S Korkusuz","Ankara University","STUDY_CHAIR",{"name":42,"affiliation":5,"role":40},"Cemre Yılmaz",{"name":44,"affiliation":5,"role":45},"Süleyman Korkusuz","PRINCIPAL_INVESTIGATOR",[47],{"name":48,"role":49,"phone":50,"phoneExt":26,"email":51},"Süleyman Korkusuz, PhD","CONTACT","+905388675480","suleyman.korkusuz@atilim.edu.tr",[53],{"facility":5,"status":26,"city":54,"state":26,"zip":26,"country":55,"countryCode":26,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Ankara","Turkey (Türkiye)",{"type":57,"coordinates":58},"Point",[59,60],32.85427,39.91987,{"lat":60,"lon":59},[63],{"name":48,"role":49,"phone":64,"phoneExt":26,"email":51},"+90 538 867 54 80",{"type":66,"investigatorFullName":44,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Assist. Prof. Dr","100657684","multiple-sclerosis-severity-and-caregiver-health-outcomes-100657684",false,"NCT07842744","Multiple Sclerosis Severity and Caregiver Health Outcomes","Associations Between Multiple Sclerosis Severity and Caregivers' Sleep Quality, Physical Activity, Body Awareness, Psychosocial Status, and Caregiver Burden: An ICF-Based Cross-Sectional Study","Inclusion Criteria:\n\n* Being 18 years of age or older.\n* Providing regular care to an individual diagnosed with multiple sclerosis for at least six months.\n* Volunteering to participate in the study.\n\nExclusion Criteria:\n\n* Having a cognitive impairment that prevents completion of the assessments.\n* Having a severe physical or psychiatric condition that may interfere with study assessments.\n* Being unable to complete the questionnaires.",true,"ALL",{"count":78,"type":79},68,"ESTIMATED","OBSERVATIONAL","This cross-sectional observational study aims to investigate the associations between multiple sclerosis (MS) severity and caregivers' sleep quality, physical activity, body awareness, perceived stress, and caregiver burden. A total of 68 caregivers of patients with MS will be recruited from Başkent University Hospital. MS severity will be assessed using the Expanded Disability Status Scale (EDSS), while caregiver health outcomes will be evaluated using validated questionnaires. The findings are expected to provide insight into the multidimensional impact of MS severity on caregiver health and well-being.",[83,84,85,86,87],"Multiple Sclerosis","Caregiver Burden","Sleep Quality","Physical Activity","Psychological Stress","NOT_YET_RECRUITING","2026-10-05",{"date":91,"type":92},"2026-10-08","ACTUAL",{"date":94,"type":79},"2026-10-20",{"date":96,"type":79},"2027-02-20",{"name":44,"class":6},1]