[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651456":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":57,"collaborators":60,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":26,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":90,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Texas at Austin","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Musical Training Intervention","EXPERIMENTAL","Participants randomized to this arm receive a 12-week intervention to teach them how to play the ukulele. The ukulele is a very manageable instrument to learn and requires less hand dexterity than other stringed instruments. Each week participants will follow the musical training intervention (MTI) protocol that provides instruction on how to tune, hold, and strum the ukulele and play basic chords. To practice the chords, they will also learn popular songs (e.g., Chain of Fools, Three Little Birds, Happy Birthday, Just the Way You Are, and Coconut). Participants will be instructed to follow each session outlined weekly and asked to practice the instrument for at least 30 minutes, 5 days a week. They will be given a paper and digital version of the MTI protocol. A member of our research team will call the participants weekly to answer any questions about the MTI protocol.",[13],"Behavioral: Music Training Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Music Listening","ACTIVE_COMPARATOR","Participants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log.",[19],"Behavioral: Music Listening",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Music Training Intervention","The Music Training Intervention (MTI) entails 12-weeks of online instruction to learn to play the ukulele. Participants will be taught the basic information on how to hold the ukulele, musical chords, strum and play popular songs. They will be instructed to play at least 30-minutes a day, five days a week.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Participants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log",[15],[31],{"name":32,"affiliation":5,"role":33},"Carolyn Phillips, PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Carolyn Phillips, PhD, RN","CONTACT","512-475-7039","carolyn.phillips@nursing.utexas.edu",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Austin","Texas","78712","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-97.74306,30.26715,{"lat":52,"lon":51},[55],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":56},"music4ms@nursing.utexas.edu",{"type":33,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Carolyn Phillips","Assistant Professor",[61],{"name":62,"class":63},"National Institute of Nursing Research (NINR)","NIH","100651456","music-4-ms-to-improve-cognition-in-people-living-with-multiple-sclerosis-a-feasibility-study-100651456",false,"NCT07759115","Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study","A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study","Inclusion Criteria:\n\n* Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive)\n* Diagnosed more than 6 months prior to starting study\n* Self-reported cognitive impairment as assessed by having at leased 5 problems \"sometimes\" or more often on the Perceived Deficits Questionnaire\n* Read, write, and understand English\n* Access to internet\n\nExclusion Criteria:\n\n* Diagnosed with another neurological condition that causes cognitive impairment\n* MS exacerbation within the last 30 days\n* Professional musician (primary source of income)","ALL","18 Years","80 Years",{"count":75,"type":76},64,"ESTIMATED","INTERVENTIONAL",[79],"NA","Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. While traditional cognitive rehabilitation methods are limited in sensory engagement, music training offers a multisensory approach that enhances neuroplasticity and improves cognitive functions. This study investigates the feasibility of Music-4-MS, a 12-week music-based eHealth intervention, to support cognitive and emotional health in individuals with MS.",[82,83,84,85,86,87,88,89],"Multiple Sclerosis","Pathologic Processes","Demyelinating Autoimmune Diseases, CNS","Autoimmune Diseases of the Nervous System","Nervous System Diseases","Demyelinating Diseases","Autoimmune Diseases","Immune System Diseases",[91],"Cognitive rehabilitation","2026-08-13",{"date":94,"type":95},"2026-08-17","ACTUAL",{"date":97,"type":95},"2026-08-10",{"date":99,"type":76},"2028-08",{"name":5,"class":6},1]