[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100472905":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":17,"armGroups":18,"interventions":23,"overallOfficials":13,"centralContacts":28,"locations":34,"responsibleParty":54,"collaborators":58,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":13,"enrollmentInfo":76,"targetDuration":79,"studyType":80,"phases":13,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":37,"whyStopped":13,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"China National Center for Cardiovascular Diseases","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Target vessel failure","Time to the incidence of target vessel failure, a composite of cardiovascular death, target vessel-related myocardial infarction, and target vessel-related revascularization.","10 year",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","PROSPECTIVE","Patients who meet the definition of Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR), that is, patients who have undergone myocardial infarction or target vessel-related revascularization ≥3 times due to coronary artery stenosis in the past year after coronary stent implantation and standard coronary heart disease conventional treatment (complete revascularization and optimal medical therapy), excluding common risk factors for coronary artery restenosis and known rheumatic autoimmune diseases, systemic vasculitis, etc.",[19],{"label":20,"type":13,"description":13,"interventionNames":21},"Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR)",[22],"Other: Treatment made by experienced clinicians",[24],{"type":25,"name":26,"description":26,"armGroupLabels":27,"otherNames":13},"OTHER","Treatment made by experienced clinicians",[20],[29],{"name":30,"role":31,"phone":32,"phoneExt":13,"email":33},"Hong Jian Wang, Dr.","CONTACT","008613910008985","hongjian.wang@gmail.com",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Jia Lei","RECRUITING","Beijing","Beijing Municipality","0086","China","CN",{"type":44,"coordinates":45},"Point",[46,47],116.39723,39.9075,{"lat":47,"lon":46},[50],{"name":51,"role":31,"phone":52,"phoneExt":13,"email":53},"Lei Jia, Doctor","008615001268624","jialei27@126.com",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Kefei Dou, MD","Director of the Department of Internal Medicine",[59,61,63,65],{"name":60,"class":25},"Chinese Academy of Medical Sciences, Fuwai Hospital",{"name":62,"class":25},"The First Hospital of Jilin University",{"name":64,"class":25},"First Affiliated Hospital Xi'an Jiaotong University",{"name":66,"class":25},"Peking Union Medical College Hospital","100472905","national-multicenter-cohort-registry-study-of-rapid-recurrences-of-coronary-unexplained-in-stent-restenosis-100472905",false,"NCT05437965","National Multicenter Cohort Registry Study of Rapid rEcurrences of Coronary Unexplained In-stent Restenosis","RECUR Registry","Inclusion Criteria:\n\n1. Age ≥ 18 years;\n2. Patients meeting the diagnostic criteria for Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR);\n3. Patients fully informed about the trial procedures who provide written informed consent.\n\nExclusion Criteria:\n\n1. Patients presenting with any of the following:\n\n   * Other severe comorbidities (e.g., malignant tumors, heart failure) with a life expectancy \\\u003C12 months;\n\n     * Known autoimmune\u002Frheumatic diseases including systemic lupus erythematosus, Takayasu arteritis, Behçet's disease, polyarteritis nodosa, Wegener granulomatosis (granulomatosis with polyangiitis), eosinophilic arteritis, giant cell arteritis, rheumatoid arthritis, or IgG4-related disease;\n\n       * Variant angina (Prinzmetal's angina);\n\n         * Coronary artery dissection;\n\n           * Thrombophilia;\n\n             * Stent underexpansion.\n2. Presence of psychiatric disorders;\n3. Known inability to complete expected study follow-up for any reason;\n4. Patients deemed ineligible for enrollment by the investigator.","ALL","18 Years",{"count":77,"type":78},1000,"ESTIMATED","10 Years","OBSERVATIONAL","This project aims to establish a clinical cohort and diagnostic assessment framework by conducting a national multicenter cohort registry study. Through the collection of patients' clinical characteristics, it will achieve the registration, management, follow-up, and analysis of patients with Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR).",[83,84,85],"Coronary Artery Disease","Arteritis","In-Stent Stenosis (Restenosis) of Coronary Artery Stent",[87,88,89],"coronary arteritis","biomarker","inflammation","2025-08-05",{"date":92,"type":93},"2025-08-08","ACTUAL",{"date":95,"type":93},"2020-06-03",{"date":97,"type":78},"2035-04-01",{"name":5,"class":6},1]