[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649382":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":22,"responsibleParty":47,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":10,"maxAge":10,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":10,"overallStatus":66,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Multiple Acyl-CoA Dehydrogenase Deficiency (MADD)",null,"Patients with a molecular and\u002For biochemical diagnosis of Multiple Acyl-CoA Dehydrogenase Deficiency (MADD).",[13],{"name":14,"affiliation":5,"role":15},"Mary Kate LoPiccolo, MD","PRINCIPAL_INVESTIGATOR",[17],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Mary Freeman, MS, CGC","CONTACT","(347) 668-9162","mary.freeman@mssm.edu",[23,39],{"facility":24,"status":10,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Children's Hospital Colorado Anschutz Medical Campus","Aurora","Colorado","80045","United States","US",{"type":31,"coordinates":32},"Point",[33,34],-104.83192,39.72943,{"lat":34,"lon":33},[37],{"name":38,"role":15,"phone":10,"phoneExt":10,"email":10},"Johan Van Hove, MD, PhD",{"facility":5,"status":10,"city":40,"state":40,"zip":41,"country":28,"countryCode":29,"cosmosGeoPoint":42,"geoPoint":46,"contacts":10},"New York","10029",{"type":31,"coordinates":43},[44,45],-74.00597,40.71427,{"lat":45,"lon":44},{"type":15,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mary LoPiccolo","Assistant Professor","100649382","natural-history-of-madd-100649382",false,"NCT07734090","Natural History of MADD","Natural History of Multiple Acyl-CoA Dehydrogenase Deficiency (MADD)","Inclusion Criteria:\n\n* Have a biochemical and\u002For molecular diagnosis of Multiple Acyl-CoA Dehydrogenase Deficiency (MADD), as confirmed by a study investigator\n* Provision of signed and dated informed consent form (and assent when applicable) from subject or subject's legal representative\n\nExclusion Criteria:\n\n\\- Presence of a major unrelated condition","ALL",{"count":59,"type":60},50,"ESTIMATED","5 Years","OBSERVATIONAL","The objective of this study is to conduct a longitudinal, observational investigation to determine the natural history of Multiple Acyl-CoA Dehydrogenase Deficiency (MADD), delineate the spectrum of its clinical features and their progression, identify biomarkers, and develop and validate patient reported outcomes.",[65],"Multiple Acyl-CoA Dehydrogenase Deficiency","NOT_YET_RECRUITING","2026-07-24",{"date":69,"type":70},"2026-07-29","ACTUAL",{"date":72,"type":60},"2026-07",{"date":74,"type":60},"2031-07",{"name":5,"class":6},2]