[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100485923":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":34,"centralContacts":41,"locations":46,"responsibleParty":78,"collaborators":29,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":29,"eligibilityCriteria":87,"healthyVolunteers":83,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":29,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":29,"overallStatus":48,"whyStopped":29,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"University of Utah","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Mindfulness","EXPERIMENTAL","A well-validated mindfulness meditation-based therapy \\[8 sessions\\] is used to teach patients to independently practice meditation to cope with pain.",[13,14],"Behavioral: Meditation","Other: Usual care",{"label":16,"type":10,"description":17,"interventionNames":18},"Meditation","A validated meditation-based therapy \\[8 sessions\\] is used to teach patients to independently practice meditation to cope with pain.",[13,14],{"label":20,"type":21,"description":22,"interventionNames":23},"Usual Care","ACTIVE_COMPARATOR","Patients will receive usual medical care for chronic low back pain.",[14],[25,30],{"type":26,"name":16,"description":27,"armGroupLabels":28,"otherNames":29},"BEHAVIORAL","Participants will complete 8 sessions of meditation training with therapy as a means of coping with chronic pain and opioid-related issues.",[16,9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Usual care","Participants will receive usual care for chronic low back pain (e.g., analgesic medication, pain management consultant from a physician, physical therapy, etc.).",[16,9,20],[35,38],{"name":36,"affiliation":5,"role":37},"Eric Garland, PhD","PRINCIPAL_INVESTIGATOR",{"name":39,"affiliation":40,"role":37},"Fadel Zeidan, PhD","University of California, San Diego",[42],{"name":36,"role":43,"phone":44,"phoneExt":29,"email":45},"CONTACT","858-822-4092","eric.garland@socwk.utah.edu",[47,67],{"facility":40,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","La Jolla","California","92093","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-117.2742,32.84727,{"lat":58,"lon":57},[61,65,66],{"name":62,"role":43,"phone":63,"phoneExt":29,"email":64},"Rachel Brewers","619-363-6407","rbrewers@health.ucsd.edu",{"name":36,"role":37,"phone":29,"phoneExt":29,"email":29},{"name":39,"role":37,"phone":29,"phoneExt":29,"email":29},{"facility":68,"status":69,"city":70,"state":71,"zip":72,"country":52,"countryCode":53,"cosmosGeoPoint":73,"geoPoint":77,"contacts":29},"Center on Mindfulness and Integrative Health Intervention Development","ACTIVE_NOT_RECRUITING","Salt Lake City","Utah","84108",{"type":55,"coordinates":74},[75,76],-111.89105,40.76078,{"lat":76,"lon":75},{"type":37,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Eric Garland","Associate Dean for Research","100485923","neural-mechanisms-of-meditation-for-opioid-treated-chronic-low-back-pain-100485923",false,"NCT05607381","Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain","Neural Mechanisms of Meditation-Based Interventions for Chronic Low Back Pain","Inclusion Criteria:\n\n1\\) men\u002Fwomen 18-65 years of age; 2) current chronic low back pain classified according to the NIH Pain Consortium task force research standards for chronic low back pain (pain on at least half the days in the past 6 months); usual back pain ≥3 on 0-10 scale with opioid medication; and 4) current use of prescription opioids for ≥3 months.\n\nExclusion Criteria:\n\n1\\) Prior experience with MBSR, MBCT, MORE, or extensive involvement in any standardized meditation training, 2) current cancer diagnosis, 3) suicide intent or attempt in the past 30 days, 4) psychosis or moderate\u002Fsevere non-opioid substance use disorder in past 6 months; 5) persons with any electronic objects or certain metal objects in their head or body that are incompatible with MRI; 6) those who have had an abnormal brain MRI in the past; 7) those unable to lie still on their back for 1 to 1.5 hours; and 8) pregnancy.","ALL","18 Years","65 Years",{"count":92,"type":93},188,"ESTIMATED","INTERVENTIONAL",[96],"NA","The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low back pain.",[99,100],"Low Back Pain","Opioid Use","2026-07-23",{"date":103,"type":104},"2026-07-27","ACTUAL",{"date":106,"type":104},"2022-11-30",{"date":108,"type":93},"2027-06-30",{"name":5,"class":6},2]