[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649944":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":38,"locations":48,"responsibleParty":73,"collaborators":26,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":26,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":51,"whyStopped":26,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"University of Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Neurodevelopmental Technique + Routine PT","EXPERIMENTAL","Participants will receive Neurodevelopmental Technique (NDT) in supine, prone, sitting, and standing positions. Exercises include bridging, trunk rotation, hip\u002Fknee\u002Fankle mobilization, bilateral weight bearing, stepping, and toe rise. Each exercise repeated 20 times per set with 2-minute rest between sets. Session duration: 65 minutes, three times per week, for 12 weeks (36 sessions total), in addition to routine physiotherapy.",[13],"Behavioral: Neurodevelopmental Technique (NDT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Comparator: Mirror Therapy + Routine PT","ACTIVE_COMPARATOR","Participants will receive Mirror Therapy using a mirror (60×90 cm) placed midsagittal to reflect the unaffected leg. Bilateral symmetrical lower limb movements include heel raises, side stepping, single leg standing, hip\u002Fknee flexion-extension with ankle dorsiflexion, and ankle eversion. Each exercise repeated 20 times per set with 2-minute rest between sets. Session duration: 60-65 minutes, three times per week, for 12 weeks (36 sessions total), in addition to routine physiotherapy.",[19],"Behavioral: Mirror Therapy (MT)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Neurodevelopmental Technique (NDT)","Participants will perform Neurodevelopmental Technique (NDT) exercises in supine, prone, sitting, and standing positions. Activities include bridging, trunk rotation, hip\u002Fknee flexion-extension, ankle mobilization, bilateral weight bearing, stepping, toe rise, and single leg standing. Each exercise is performed 20 times per set with 2-minute rest intervals. Sessions last 65 minutes, three times per week, for 12 weeks (36 sessions), combined with routine physiotherapy.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Mirror Therapy (MT)","Patient sits with mirror (60×90 cm) reflecting unaffected leg. Performs bilateral symmetrical movements: heel raises, side stepping, single leg standing, hip\u002Fknee flexion-extension with ankle dorsiflexion, ankle eversion.\n\nEach exercise 20× per set, 2 min rest between sets. 60-65 min\u002Fsession, 3×\u002Fweek, for 12 weeks (36 sessions).",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Iqra Abdul Jabbar, MSPTN","Faculty of Allied Health Sciences, University Institute of Physical Therapy, University of Lahore","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":34,"role":35},"Hafiza Sana Ashraf, MSPT MSK",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":26,"email":43},"Ishaq Ahmed, PHD Ishaq Ahmed, PHD, PHD","CONTACT","Telephone: 0334 4066 463","ishaq.ahmed@uipt.uol.edu.pk",{"name":45,"role":41,"phone":46,"phoneExt":26,"email":47},"Ashfaq Ahmed","Telephone: 03009449192","ashfaq.ahmad@uipt.uol.edu.pk",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"University of Lahore teaching hospital","RECRUITING","Lahore","Punjab Province","55150","Pakistan","PK",{"type":58,"coordinates":59},"Point",[60,61],74.35071,31.558,{"lat":61,"lon":60},[64,67,71],{"name":33,"role":41,"phone":65,"phoneExt":26,"email":66},"03044218624","ciqra4352@gmail.com",{"name":68,"role":41,"phone":69,"phoneExt":26,"email":70},"Muhammad Asim, Arif","03216597727","asim.arif@uipt.uol.edu.pk",{"name":72,"role":35,"phone":26,"phoneExt":26,"email":26},"Hafiza Sana Ashraf, MS-MSK",{"type":74,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100649944","neurodevelopmental-technique-versus-mirror-therapy-in-sub-acute-stroke-patients-100649944",false,"NCT07742020","Neurodevelopmental Technique Versus Mirror Therapy in Sub-acute Stroke Patients","Effects of Neurodevelopmental Technique Versus Mirror Therapy on Coordination, Functions and Ambulation in Sub-acute Hemiplegic Stroke Patients","NDTVSMT","Inclusion Criteria:\n\nAge range between 45 to 65 years\n\n* Both genders\n* Sub-acute stroke hemiplegic cases; clinically stable, fully oriented and conscious.\n* Both ischemic and hemorrhagic patients were be included.\n* Patients with mini mental status examination (MMSE) (score \\> 23)\n\nExclusion Criteria:\n\n* Patients had recurrent stroke.\n* Any systemic conditions that limit functions such as; cardiac diseases (exertional dyspnea, angina, Myocardial Infarction, Pacemaker) Pulmonary diseases (Asthma, Pulmonary Fibrosis etc.), Diabatic neuropathy, Diabetic foot, Varicose veins etc\n* Other neurological conditions, such as; foot drop, muscular dystrophy, Myasthenia Gravis, Parkinsonism\n* Any visual and hearing problem\n* Any surgical and traumatic history of fractures, dislocations and\u002For brain injury due to any traumatic events.","ALL","45 Years","65 Years",{"count":87,"type":88},40,"ESTIMATED","INTERVENTIONAL",[91],"NA","As neurodevelopmental technique and mirror therapy had different effects on lower limb coordination, functions and ambulation. Both had proven to be helpful in the stroke patients to gain functional independency. Therefore, there was need to find out the best treatment approach either NDT, mirror therapy or both are equally effective to improve motor functions, coordination and ambulation of lower limb. This study would provide the health professionals the evidence to use best technique among these according to improvement in patients' coordination, function and ambulation.The study will be randomized clinical trial. This study will be conducted at the University of Lahore. A sample size of 40 will be randomly allocated by into two experimentals groups, (20 participants in each group), by the lottery method. All the screened and willing participants will be randomly allocated to two groups (Group A: Experimental group Neurodevelopmental technique, Group B: Experimental Group mirror therapy exercise) by lottery method. This study will be a single blinded study in which assessor will be blinded.",[94,95,96],"Hemiplegia","Subacute Stroke","Stroke Rehabilitation",[23,28,98,99,100,101,102,103,104,105],"stroke","subacute stroke","hemiplegia","motor function","balance","coordination","ambulation","rehabilitation","2026-07-28",{"date":108,"type":109},"2026-08-03","ACTUAL",{"date":111,"type":109},"2025-09-08",{"date":113,"type":88},"2026-08-15",{"name":5,"class":6},1]