[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655192":3},{"organization":4,"outcomesModule":7,"designInfo":42,"detailedDescription":16,"studyPopulation":45,"armGroups":16,"interventions":16,"overallOfficials":16,"centralContacts":46,"locations":55,"responsibleParty":73,"collaborators":16,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":16,"studyType":88,"phases":16,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":99,"whyStopped":16,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"University Hospital, Lille","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":16},[9],{"measure":10,"description":11,"timeFrame":12},"Prospectively study, among the leguminous, the type of leguminous (excluding peanut) responsible for the allergy.","The primary endpoint will be the number of allergy diagnoses for each type of leguminous (excluding peanut), among :\n\n* Green peas\n* Split peas (dried green peas)\n* Yellow or blond dried peas\n* Chickpeas\n* Green, red, or blond lentils\n* Green, Kidney, White or Mung beans\n* Soybean\n* Lupin\n* Fenugreek\n* Fava bean (broad bean)\n* Beluga lentils\n* Black-eyed peas (cowpeas), adzuki beans,and urad beans\n* Alfalfa","Baseline (Inclusion) 1 Year from the Inclusion 5 years from the inclusion, or until the age of 18",[14,18,21,23,26,28,30,32,34,36,38,40],{"measure":15,"description":16,"timeFrame":17},"Describe the age at onset and severity of the first manifestation",null,"Baseline (Inclusion)",{"measure":19,"description":20,"timeFrame":17},"Describe quality of life (FAQLQ questionnaires) in children aged 8 years or older","Food Allergy Quality of Life Questionnaire : several forms tailored to the patient's age or intended for family members:\n\n* FAQLQ-PF (Parent Form): for parents of children aged 0 to 12;\n* FAQLQ-CF (Child Form): for children aged 8 to 12;\n* FAQLQ-TF (Teenager Form): for adolescents;\n* FAQLQ-PTF (for parents of adolescents).\n\nEach item is rated on a scale of 1 to 7 (Minimum Value = 1 and Maximum Value =7).\n\nDepending on the specific FAQLQ instrument used, the number of items varies, resulting in different minimum and maximum total scores :\n\n* FAQLQ-CF: Total score ranges from 24 to 204\n* FAQLQ-TF: Total score ranges from 29 to 203\n* FAQLQ-PF: Total score ranges from 0 to 180\n* FAQLQ-PTF: Total score ranges from 0 to 186\n\nHigher scores indicate a worse outcome.",{"measure":22,"description":16,"timeFrame":17},"Establish a biobank (blood - plasma samples) to validate future diagnostic tests",{"measure":24,"description":25,"timeFrame":12},"Describe the severity of reactions by legume (FASS score)","Title: Food Allergy Severity Score. Scores range from a minimum of 1 (representing a mild allergic reaction) to a maximum of 5 (representing a very severe allergic reaction).\n\nHigher scores indicate a worse outcome.",{"measure":27,"description":16,"timeFrame":12},"Describe the frequency of anaphylaxis by legume (according to the WAO definition)",{"measure":29,"description":16,"timeFrame":12},"Describe the frequency of severe anaphylaxis by legume (FASS-5 Grades 4 and 5)",{"measure":31,"description":16,"timeFrame":12},"Describe associations between allergies to different leguminous.",{"measure":33,"description":16,"timeFrame":12},"Describe allergic comorbidities (asthma, rhinitis, atopic dermatitis, and pollinosis)",{"measure":35,"description":16,"timeFrame":12},"Describe associated food allergies, including peanut and other foods",{"measure":37,"description":16,"timeFrame":12},"Describe allergy management strategies: targeted avoidance, broad avoidance, emergency kit with an adrenaline auto-injector, and school-based management (Individualized Healthcare Plan)",{"measure":39,"description":16,"timeFrame":12},"Assess parents' knowledge of the different leguminous",{"measure":41,"description":16,"timeFrame":12},"Prospectively assess allergic reactions in real-life settings: number of reactions, severity, type of food (prepackaged ready-made meal or homemade meal), labeling, quantity consumed, location of occurrence, and management",{"allocation":16,"interventionModel":16,"interventionModelDescription":16,"primaryPurpose":16,"observationalModel":43,"timePerspective":44,"maskingInfo":16},"COHORT","PROSPECTIVE","Cohort of patients with the disease (leguminous allergy), between 6 months to 17 years old, with medical follow up in Pneumo-allergy unit - CHU Lille",[47,52],{"name":48,"role":49,"phone":50,"phoneExt":16,"email":51},"Celine CLAIRET-LESPINASSE","CONTACT","+33 3204441145","celine.clairet@chu-lille.fr",{"name":53,"role":49,"phone":50,"phoneExt":16,"email":54},"DRS. Promotion","drs.promotion@chu-lille.fr",[56],{"facility":57,"status":16,"city":58,"state":16,"zip":16,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"CHU Lille","Lille","France","FR",{"type":62,"coordinates":63},"Point",[64,65],3.05512,50.63391,{"lat":65,"lon":64},[68,70],{"name":48,"role":49,"phone":69,"phoneExt":16,"email":51},"+33320444145",{"name":71,"role":72,"phone":16,"phoneExt":16,"email":16},"Marie MOYART, Doctor","PRINCIPAL_INVESTIGATOR",{"type":74,"investigatorFullName":16,"investigatorTitle":16,"investigatorAffiliation":16,"oldNameTitle":16,"oldOrganization":16},"SPONSOR","100655192","observational-study-of-ige-mediated-leguminous-allergies-in-a-pediatric-population-100655192",false,"NCT07811141","Observational Study of IgE-Mediated Leguminous Allergies in a Pediatric Population","FabALL","Inclusion Criteria:\n\n* Subjects aged 6 months to 17 years old\n* Medical diagnosis of allergy to one or more leguminous :\n* Clinical reaction following real-life exposure AND positive skin and\u002For biological sensitization\n* Allergy confirmed by a positive oral food challenge (OFC) in cases of sensitization without a history of clinical reaction\n* Subjects seen in a pediatric pneumo-allergy unit (consultation or hospitalization)\n\nExclusion Criteria:\n\n* Isolated IgE-mediated peanut allergy\n* Patients aged 18 years or older\n* Minor patient or legal representant (parental authority) Refusal","ALL","6 Months","17 Years",{"count":86,"type":87},100,"ESTIMATED","OBSERVATIONAL","Prospective, monocentric, observational study with standard care follow-up during 5 years or until the patient reaches the age of 18.\n\nThe aim of this study is to prospectively and comprehensively assess the characteristics of patients aged 6 months to 17 years with leguminous allergy (excluding peanut) and their reactions to leguminous, including both medical history and prospective follow-up for 5 years from inclusion, or until the age of 18. The study aims to improve the understanding of these allergies, provide epidemiological data, and optimize diagnostic and clinical management. A biobank will also be established, with plasma (one whole blood sample collected at the inclusion) in order to validate future diagnostic tests.",[91,92],"Hypersensitivity, Food","Legumes Allergy",[94,95,96,97,98],"food hypersensitivity","allergy","fabaceae","leguminous","biobank","NOT_YET_RECRUITING","2026-09-28",{"date":102,"type":103},"2026-10-01","ACTUAL",{"date":105,"type":87},"2026-09",{"date":107,"type":87},"2034-09",{"name":5,"class":6},1]