[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613856":3},{"organization":4,"outcomesModule":7,"designInfo":52,"detailedDescription":11,"studyPopulation":11,"armGroups":60,"interventions":83,"overallOfficials":11,"centralContacts":100,"locations":106,"responsibleParty":123,"collaborators":11,"id":127,"slug":128,"hasResults":129,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":11,"eligibilityCriteria":133,"healthyVolunteers":129,"sex":134,"minAge":135,"maxAge":11,"enrollmentInfo":136,"targetDuration":11,"studyType":139,"phases":140,"briefSummary":142,"conditions":143,"keywords":11,"overallStatus":109,"whyStopped":11,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":156},{"fullName":5,"class":6},"Riga Stradins University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":32},[9,13],{"measure":10,"description":11,"timeFrame":12},"Change from Baseline in Morning Resting Heart Rate Variability (rMSSD) at 4 Weeks",null,"Baseline, Periprocedural and Week 4",{"measure":14,"description":11,"timeFrame":15},"Change from Baseline in Perceived Stress Level (PSS-10 Score) at 4 Weeks","Baseline and Week 4",[17,19,21,23,25,27,30],{"measure":18,"description":11,"timeFrame":15},"Sleep Quality: Assessed using the Pittsburgh Sleep Quality Index (PSQI) total score",{"measure":20,"description":11,"timeFrame":15},"General Self-Efficacy: Assessed using the General Self-Efficacy Scale (GSE) score",{"measure":22,"description":11,"timeFrame":15},"Emotional Well-being: Assessed using the World Health Organization Well-being Index (WHO-5) score",{"measure":24,"description":11,"timeFrame":15},"Neck Functional Limitation: Assessed using the Neck Disability Index (NDI) score",{"measure":26,"description":11,"timeFrame":15},"Hand and Shoulder Functionality: Assessed using the Disabilities of the Arm, Shoulder, and Hand (DASH) Questionnaire score",{"measure":28,"description":11,"timeFrame":29},"Acute Pain Intensity Change: Assessed using the Numerical Rating Scale (NRS) score (0-10) in the specific massage area","Periprocedural",{"measure":31,"description":11,"timeFrame":29},"Acute Subjective Well-being Change: Assessed using the Visual Analog Scale (VAS) (0-100 mm) for relaxation, fatigue, and tension",[33,37,40,43,46,49],{"measure":34,"description":35,"timeFrame":36},"Age of Participants","The age of participants calculated from their date of birth. Years","Baseline",{"measure":38,"description":39,"timeFrame":36},"Smoking Status Categories","The classification of participants' smoking status (e.g., Current Smoker, Former Smoker, Never Smoker). Count (Number of Participants per Category)",{"measure":41,"description":42,"timeFrame":36},"Body Mass Index (BMI)","Body Mass Index, calculated from weight and height. kg\u002Fm2",{"measure":44,"description":45,"timeFrame":36},"Duration of Sedentary Work Experience","The total duration of sedentary work experience. Years",{"measure":47,"description":48,"timeFrame":36},"Family and Parental Status Categories","The classification of participants based on their family and parental status (e.g., Married, Unmarried, With Children, Without Children). Count (Number of Participants per Category)",{"measure":50,"description":51,"timeFrame":36},"Total Physical Activity Level (IPAQ)","Total physical activity level score calculated using the International Physical Activity Questionnaire (IPAQ) short form. Metabolic Equivalent of Task (MET) -minutes\u002Fweek",{"allocation":53,"interventionModel":54,"interventionModelDescription":11,"primaryPurpose":55,"observationalModel":11,"timePerspective":11,"maskingInfo":56},"NON_RANDOMIZED","PARALLEL","TREATMENT",{"masking":57,"maskingDescription":11,"whoMasked":58},"SINGLE",[59],"OUTCOMES_ASSESSOR",[61,67,72,77],{"label":62,"type":63,"description":64,"interventionNames":65},"Head Massage","ACTIVE_COMPARATOR","Duration and Frequency: 15 minutes per session, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Massage focuses on the scalp, temples, and auricles (outer ear) with the aim of stimulating cranial nerves, particularly branches of the vagus nerve. The procedure is performed by a licensed massage therapist while the participant is seated in an office chair.",[66],"Procedure: Head Massage Intervention",{"label":68,"type":63,"description":69,"interventionNames":70},"Cervical Area Massage","Duration and Frequency: 15 minutes per session, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Deep tissue and kneading massage techniques applied primarily to the trapezius muscles, levator scapulae, and sub-occipital region (neck\u002Fshoulders). The procedure is performed by a licensed massage therapist while the participant is seated in an office chair.",[71],"Procedure: Cervical Area Massage Intervention",{"label":73,"type":63,"description":74,"interventionNames":75},"Hand Massage","Duration and Frequency: 15 minutes per session, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Compression, rubbing, and stroking techniques applied to the palmar and dorsal surfaces of the hands, fingers, and wrists. The procedure is performed by a licensed massage therapist while the participant is seated in an office chair.",[76],"Procedure: Hand Massage Intervention",{"label":78,"type":79,"description":80,"interventionNames":81},"Quiet Rest Control","PLACEBO_COMPARATOR","Duration and Frequency: Participants are seated in the same office chair for a structured 15-minute period, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Participants are instructed to sit quietly, avoid work-related activity, and refrain from using electronic devices. This arm controls for the effect of researcher attention and time spent away from work.",[82],"Other: Quiet Rest Control",[84,89,93,97],{"type":85,"name":86,"description":87,"armGroupLabels":88,"otherNames":11},"PROCEDURE","Head Massage Intervention","15 minutes per session, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Massage focuses on the scalp, temples, and auricles (outer ear) with the aim of stimulating cranial nerves, particularly branches of the vagus nerve. The procedure is performed by a licensed massage therapist while the participant is seated in an office chair.",[62],{"type":85,"name":90,"description":91,"armGroupLabels":92,"otherNames":11},"Cervical Area Massage Intervention","15 minutes per session, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Deep tissue and kneading massage techniques applied primarily to the trapezius muscles, levator scapulae, and sub-occipital region (neck\u002Fshoulders). The procedure is performed by a licensed massage therapist while the participant is seated in an office chair.",[68],{"type":85,"name":94,"description":95,"armGroupLabels":96,"otherNames":11},"Hand Massage Intervention","15 minutes per session, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Compression, rubbing, and stroking techniques applied to the palmar and dorsal surfaces of the hands, fingers, and wrists. The procedure is performed by a licensed massage therapist while the participant is seated in an office chair.",[73],{"type":6,"name":78,"description":98,"armGroupLabels":99,"otherNames":11},"Participants are seated in the same office chair for a structured 15-minute period, 2 times per week for 4 consecutive weeks (8 sessions total). Focus: Participants are instructed to sit quietly, avoid work-related activity, and refrain from using electronic devices. This arm controls for the effect of researcher attention and time spent away from work.",[78],[101],{"name":102,"role":103,"phone":104,"phoneExt":11,"email":105},"Una Veseta, PhD","CONTACT","+37129172627","una.veseta@rsu.lv",[107],{"facility":108,"status":109,"city":110,"state":111,"zip":112,"country":111,"countryCode":113,"cosmosGeoPoint":114,"geoPoint":119,"contacts":120},"The Red Cross Medical College of Rīga Stradiņš University","RECRUITING","Riga","Latvia","LV-1007","LV",{"type":115,"coordinates":116},"Point",[117,118],24.10589,56.946,{"lat":118,"lon":117},[121],{"name":122,"role":103,"phone":104,"phoneExt":11,"email":105},"Una Veseta, dr paed",{"type":124,"investigatorFullName":125,"investigatorTitle":126,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Una Veseta","Lead Researcher","100613856","office-massage-effects-on-hrv-and-stress-100613856",false,"NCT07272031","Office Massage Effects on HRV and Stress","Randomized Controlled Trial to Evaluate the Effectiveness of Three Different 15-Minute Office Massage Types (Head, Cervical Area, Hand) on Autonomic Nervous System Balance and Chronic Stress Reduction Using Heart Rate Variability (HRV)","Inclusion Criteria:\n\nBiological females aged 18 years or older. Currently working in an office job with at least 75% of the working day spent sitting (sedentary work).\n\nSelf-reported regular menstrual cycle (cycle length 21-35 days). Able to attend all scheduled intervention sessions (8 sessions over 4 weeks). Able to provide informed consent to participate in the study.\n\nExclusion Criteria:\n\nCurrent pregnancy or breastfeeding. Diagnosis of cardiovascular diseases (e.g., heart failure, cardiac arrhythmias, deep vein thrombosis) or presence of a pacemaker Endocrine or metabolic disorders (e.g., insulin-dependent diabetes, hyperthyroidism, or other thyroid dysfunctions) Active cancer or receiving active cancer treatment (e.g., chemotherapy, radiation therapy) History of major surgery or trauma in the head, neck, or upper extremities within the last 3 months Current diagnosis of a major psychiatric disorder (e.g., major depressive disorder, bipolar disorder) Regular use of medications affecting heart rate or the nervous system (e.g., beta-blockers, ACE inhibitors, antidepressants, anxiolytics, or asthma inhalers) Current participation in another interventional clinical trial","FEMALE","18 Years",{"count":137,"type":138},140,"ESTIMATED","INTERVENTIONAL",[141],"NA","This study is a randomized controlled trial designed to investigate which of three short office massage types (head, neck\u002Fshoulder area, or hand) is most effective for reducing chronic stress in women who perform sedentary office work.\n\nMany sedentary female office employees experience long-term tension and work-related strain, which can affect the body's ability to recover. The investigators are testing whether a 15-minute massage, performed twice a week for four weeks, can help restore balance within the body.\n\nThe investigators will evaluate the impact of these massages using Heart Rate Variability (HRV)-an objective measure that shows how well the body manages stress (autonomic nervous system balance)-as well as analyzing participants' self-reported levels of perceived stress, sleep quality, and overall well-being. Participants receiving massage will be compared to a control group engaging in quiet rest.",[144,145,146],"Occupational Health","Autonomic Nervous System (ANS) Functioning and Mood State","Stress","2026-08-12",{"date":149,"type":150},"2026-08-13","ACTUAL",{"date":152,"type":150},"2026-01-05",{"date":154,"type":138},"2026-09-30",{"name":5,"class":6},1]