[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655088":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":17,"studyPopulation":17,"armGroups":24,"interventions":35,"overallOfficials":17,"centralContacts":41,"locations":47,"responsibleParty":66,"collaborators":17,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":17,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":50,"whyStopped":17,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Fudan University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"Incidence of Postoperative Chylothorax","Percentage of participants diagnosed with postoperative chylothorax. Chylothorax is defined as pleural drainage fluid triglycerides greater than 110 mg\u002FdL (1.2 mmol\u002FL) or a typical milky appearance of pleural drainage after resumption of oral dietary fat.","Within 30 days after surgery",[14],{"measure":15,"description":16,"timeFrame":12},"Incidence of Postoperative Complications","Percentage of participants with one or more surgery-related postoperative complications, including prolonged air leak, atrial fibrillation or other arrhythmia, postoperative bleeding, pulmonary infection, respiratory insufficiency, bronchopleural fistula, pneumothorax or atelectasis, recurrent laryngeal nerve injury, or death.",null,{"allocation":19,"interventionModel":20,"interventionModelDescription":17,"primaryPurpose":21,"observationalModel":17,"timePerspective":17,"maskingInfo":22},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":23,"maskingDescription":17,"whoMasked":17},"NONE",[25,31],{"label":26,"type":27,"description":28,"interventionNames":29},"Preoperative Olive Oil","EXPERIMENTAL","Participants drink 40 mL of extra-virgin olive oil 4 hours before surgery and then continue fasting from food and water until surgery.",[30],"Dietary Supplement: Extra-Virgin Olive Oil",{"label":32,"type":33,"description":34,"interventionNames":17},"Standard Preoperative Fasting","NO_INTERVENTION","Participants follow each center's standard preoperative fasting regimen: no food for 8 hours and no water for 2 hours before surgery. No additional olive oil is given.",[36],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":17},"DIETARY_SUPPLEMENT","Extra-Virgin Olive Oil","A single 40 mL dose of extra-virgin olive oil is taken orally 4 hours before curative lung cancer surgery. After ingestion, participants continue fasting from food and water until surgery.",[26],[42],{"name":43,"role":44,"phone":45,"phoneExt":17,"email":46},"Hang Cao, MD","CONTACT","+86 18717722753","16301050173@fudan.edu.cn",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Fudan University Shanghai Cancer Center","RECRUITING","Shanghai","Xuhui","200000","China","CN",{"type":57,"coordinates":58},"Point",[59,60],121.45806,31.22222,{"lat":60,"lon":59},[63],{"name":64,"role":44,"phone":65,"phoneExt":17,"email":46},"Yang Zhang, MD","86-18717722753",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Haiquan Chen","director of thoracic surgery department","100655088","olive-oil-before-lung-cancer-surgery-to-prevent-chylothorax-100655088",false,"NCT07807696","Olive Oil Before Lung Cancer Surgery to Prevent Chylothorax","A Multicenter, Prospective, Randomized Controlled Trial of Preoperative Oral Olive Oil for the Prevention of Postoperative Chylothorax in Patients With Lung Cancer","ECTOP-1031","Inclusion Criteria:\n\n* Voluntary participation and willing and able to complete all study procedures.\n* Age 18 to 80 years, inclusive, at informed consent.\n* Eastern Cooperative Oncology Group performance status of 0 or 1.\n* Resectable lung cancer.\n* No prior surgery for lung cancer.\n* Treatment-naive and no prior radiotherapy or chemotherapy.\n* Able to take food orally before surgery.\n\nExclusion Criteria:\n\n* Allergy to olive oil or any of its components.\n* History of acute or chronic pancreatitis or severe biliary disease.\n* Fat malabsorption syndrome.\n* Prior ipsilateral thoracic surgery or thoracic radiotherapy or chemotherapy.\n* Unable to comply with preoperative dietary instructions.","ALL","18 Years","80 Years",{"count":82,"type":83},1036,"ESTIMATED","INTERVENTIONAL",[86],"NA","Chylothorax is a rare but serious complication after lung cancer surgery and mediastinal lymph node dissection. This multicenter randomized trial will evaluate whether drinking 40 mL of extra-virgin olive oil 4 hours before surgery can reduce the occurrence of chylothorax after curative lung cancer resection. A total of 1,036 adults with resectable lung cancer will be assigned in a 1:1 ratio to preoperative oral olive oil or standard preoperative fasting without additional olive oil. The primary outcome is the occurrence of chylothorax within 30 days after surgery. Secondary outcomes include repeat surgery, postoperative complications, chest drainage, length of chest tube use, length of hospital stay, and the safety and tolerability of the intervention.",[89,90],"Lung Cancer","Chylothorax",[92,93,94],"Olive Oil","Thoracic Duct","Postoperative Complications","2026-09-03",{"date":97,"type":98},"2026-09-08","ACTUAL",{"date":100,"type":98},"2026-03-15",{"date":102,"type":83},"2030-12-30",{"name":5,"class":6},1]