[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650107":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":242,"collaborators":25,"id":245,"slug":246,"hasResults":247,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":251,"eligibilityCriteria":252,"healthyVolunteers":247,"sex":253,"minAge":254,"maxAge":25,"enrollmentInfo":255,"targetDuration":25,"studyType":258,"phases":259,"briefSummary":261,"conditions":262,"keywords":264,"overallStatus":269,"whyStopped":25,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":274,"completionDateStruct":276,"leadSponsor":278,"locationsCount":279},{"fullName":5,"class":6},"Chonnam National University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"In-hospital staged complete revascularization","EXPERIMENTAL","In the in-hospital staged complete revascularization group, PCI of non-IRA lesions will be performed on a separate day during the index hospitalization, at least 48 hours after PCI of the IRA. Non-IRA lesion which have equal or more than 70% diameter stenosis by visual estimation will be revascularized without FFR evaluation. Non-IRA lesion with diameter stenosis 50-69% by visual estimation will be evaluated using FFR device. In case of FFR value more than 0.8, non-IRA lesion will be deferred without PCI. If FFR value was equal or less than 0.8, non-IRA lesion will be revascularized.",[13],"Procedure: In-hospital staged complete revascularization",{"label":15,"type":16,"description":17,"interventionNames":18},"Out-of-hospital staged complete revascularization","ACTIVE_COMPARATOR","In the out-of-hospital staged complete revascularization group, PCI of non-IRA lesions will be performed after discharge and between 15 and 45 days of randomization. Non-IRA lesion which have equal or more than 70% diameter stenosis by visual estimation will be revascularized without FFR evaluation. Non-IRA lesion with diameter stenosis 50-69% by visual estimation will be evaluated using FFR device. In case of FFR value more than 0.8, non-IRA lesion will be deferred without PCI. If FFR value was equal or less than 0.8, non-IRA lesion will be revascularized.",[19],"Procedure: Out-of-hospital staged complete revascularization",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","PCI of non-IRA lesions will be performed on a separate day during the index hospitalization, at least 48 hours after PCI of the IRA. Non-IRA lesion which have equal or more than 70% diameter stenosis by visual estimation will be revascularized without FFR evaluation. Non-IRA lesion with diameter stenosis 50-69% by visual estimation will be evaluated using FFR device. In case of FFR value more than 0.8, non-IRA lesion will be deferred without PCI. If FFR value was equal or less than 0.8, non-IRA lesion will be revascularized.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"PCI of non-IRA lesions will be performed after discharge and between 15 and 45 days of randomization. Non-IRA lesion which have equal or more than 70% diameter stenosis by visual estimation will be revascularized without FFR evaluation. Non-IRA lesion with diameter stenosis 50-69% by visual estimation will be evaluated using FFR device. In case of FFR value more than 0.8, non-IRA lesion will be deferred without PCI. If FFR value was equal or less than 0.8, non-IRA lesion will be revascularized.",[15],[30],{"name":31,"affiliation":5,"role":32},"Youngkeun Ahn, MD, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Min Chul Kim, MD, PhD","CONTACT","82-10-4606-2643","kmc3242@hanmail.net",[40,50,58,63,71,79,87,95,100,105,110,118,125,130,135,140,148,156,164,169,177,185,190,195,200,208,213,218,226,234],{"facility":41,"status":25,"city":42,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":44,"geoPoint":49,"contacts":25},"Bucheon Sejong Hospital","Bucheon-si","South Korea",{"type":45,"coordinates":46},"Point",[47,48],126.78306,37.49889,{"lat":48,"lon":47},{"facility":51,"status":25,"city":52,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":53,"geoPoint":57,"contacts":25},"Gyeongsang National University Changwon Hospital","Changwon",{"type":45,"coordinates":54},[55,56],128.68111,35.22806,{"lat":56,"lon":55},{"facility":59,"status":25,"city":52,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":60,"geoPoint":62,"contacts":25},"Samsung Changwon Medical Center",{"type":45,"coordinates":61},[55,56],{"lat":56,"lon":55},{"facility":64,"status":25,"city":65,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":66,"geoPoint":70,"contacts":25},"Soon Chun Hyang University Hospital Cheonan","Cheonan",{"type":45,"coordinates":67},[68,69],127.1522,36.8065,{"lat":69,"lon":68},{"facility":72,"status":25,"city":73,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":74,"geoPoint":78,"contacts":25},"Chungbuk National University Hospital","Cheongju-si",{"type":45,"coordinates":75},[76,77],127.48972,36.63722,{"lat":77,"lon":76},{"facility":80,"status":25,"city":81,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":82,"geoPoint":86,"contacts":25},"Kangwon National University Hospital","Chuncheon",{"type":45,"coordinates":83},[84,85],127.73417,37.87472,{"lat":85,"lon":84},{"facility":88,"status":25,"city":89,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":90,"geoPoint":94,"contacts":25},"Daegu Catholic University Medical Center","Daegu",{"type":45,"coordinates":91},[92,93],128.59111,35.87028,{"lat":93,"lon":92},{"facility":96,"status":25,"city":89,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":97,"geoPoint":99,"contacts":25},"Keimyung University Dongsan Hospital",{"type":45,"coordinates":98},[92,93],{"lat":93,"lon":92},{"facility":101,"status":25,"city":89,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":102,"geoPoint":104,"contacts":25},"Kyungpook National University Hospital",{"type":45,"coordinates":103},[92,93],{"lat":93,"lon":92},{"facility":106,"status":25,"city":89,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":107,"geoPoint":109,"contacts":25},"Yeongnam University Medical Center",{"type":45,"coordinates":108},[92,93],{"lat":93,"lon":92},{"facility":111,"status":25,"city":112,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":113,"geoPoint":117,"contacts":25},"Chungnam National University Hospital","Daejeon",{"type":45,"coordinates":114},[115,116],127.38493,36.34913,{"lat":116,"lon":115},{"facility":5,"status":25,"city":119,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":120,"geoPoint":124,"contacts":25},"Gwangju",{"type":45,"coordinates":121},[122,123],126.91556,35.15472,{"lat":123,"lon":122},{"facility":126,"status":25,"city":119,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":127,"geoPoint":129,"contacts":25},"Chosun University Hospital",{"type":45,"coordinates":128},[122,123],{"lat":123,"lon":122},{"facility":131,"status":25,"city":119,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":132,"geoPoint":134,"contacts":25},"Gwangju Veterans Hospital",{"type":45,"coordinates":133},[122,123],{"lat":123,"lon":122},{"facility":136,"status":25,"city":119,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":137,"geoPoint":139,"contacts":25},"Kwangju Christian Hospital",{"type":45,"coordinates":138},[122,123],{"lat":123,"lon":122},{"facility":141,"status":25,"city":142,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":143,"geoPoint":147,"contacts":25},"Chung-Ang University Gwangmyeong Hospital","Gwangmyeong",{"type":45,"coordinates":144},[145,146],126.86639,37.47722,{"lat":146,"lon":145},{"facility":149,"status":25,"city":150,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":151,"geoPoint":155,"contacts":25},"Jeju National University Hospital","Jeju City",{"type":45,"coordinates":152},[153,154],126.52194,33.50972,{"lat":154,"lon":153},{"facility":157,"status":25,"city":158,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":159,"geoPoint":163,"contacts":25},"Jeonbuk National University Hospital","Jeonju",{"type":45,"coordinates":160},[161,162],127.14889,35.82194,{"lat":162,"lon":161},{"facility":165,"status":25,"city":158,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":166,"geoPoint":168,"contacts":25},"Presbyterian Medical Center",{"type":45,"coordinates":167},[161,162],{"lat":162,"lon":161},{"facility":170,"status":25,"city":171,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":172,"geoPoint":176,"contacts":25},"Gyeongsang National University Hospital","Jinju",{"type":45,"coordinates":173},[174,175],128.08472,35.19278,{"lat":175,"lon":174},{"facility":178,"status":25,"city":179,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":180,"geoPoint":184,"contacts":25},"Inje University Busan Paik Hospital","Pusan",{"type":45,"coordinates":181},[182,183],128.02524,35.70128,{"lat":183,"lon":182},{"facility":186,"status":25,"city":179,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":187,"geoPoint":189,"contacts":25},"Inje University Haeundae Paik Hospital",{"type":45,"coordinates":188},[182,183],{"lat":183,"lon":182},{"facility":191,"status":25,"city":179,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":192,"geoPoint":194,"contacts":25},"Kosin University Gospel Hospital",{"type":45,"coordinates":193},[182,183],{"lat":183,"lon":182},{"facility":196,"status":25,"city":179,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":197,"geoPoint":199,"contacts":25},"Pusan National University Hospital",{"type":45,"coordinates":198},[182,183],{"lat":183,"lon":182},{"facility":201,"status":25,"city":202,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":203,"geoPoint":207,"contacts":25},"Koera University Guro Hospital","Seoul",{"type":45,"coordinates":204},[205,206],126.9784,37.566,{"lat":206,"lon":205},{"facility":209,"status":25,"city":202,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":210,"geoPoint":212,"contacts":25},"Korea University Anam Hospital",{"type":45,"coordinates":211},[205,206],{"lat":206,"lon":205},{"facility":214,"status":25,"city":202,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":215,"geoPoint":217,"contacts":25},"Yonsei University Health System, Gangnam Severance Hospital",{"type":45,"coordinates":216},[205,206],{"lat":206,"lon":205},{"facility":219,"status":25,"city":220,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":221,"geoPoint":225,"contacts":25},"St. Carollo General Hospital","Suncheon",{"type":45,"coordinates":222},[223,224],127.48784,34.9505,{"lat":224,"lon":223},{"facility":227,"status":25,"city":228,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":229,"geoPoint":233,"contacts":25},"Ajou University Hospital","Suwon",{"type":45,"coordinates":230},[231,232],127.00889,37.29111,{"lat":232,"lon":231},{"facility":235,"status":25,"city":236,"state":25,"zip":25,"country":43,"countryCode":25,"cosmosGeoPoint":237,"geoPoint":241,"contacts":25},"Pusan National University Yangsan Hospital","Yangsan",{"type":45,"coordinates":238},[239,240],129.03358,35.34199,{"lat":240,"lon":239},{"type":32,"investigatorFullName":243,"investigatorTitle":244,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Min Chul Kim","Professor","100650107","optimal-timing-of-staged-complete-revascularization-in-stemi-with-multivessel-disease-100650107",false,"NCT07741721","Optimal Timing of Staged Complete Revascularization in STEMI With Multivessel Disease","OPtimal TIming of Staged Complete RevascularizatiON in ST-Segment Elevation Myocardial Infarction With Multivessel Disease: The OPTION-STEMI2 Trial","OPTION-STEMI2","Inclusion Criteria:\n\n* Age ≥19 years\n* ST-segment elevation myocardial infarction (STEMI): ST-segment elevation ≥ 0.1 mV in at least two contiguous leads, or New-onset left bundle branch block (LBBB)\n* Primary PCI within 12 h after symptom development\n* At least 1 non-infarct related artery (non-IRA) with diameter ≥ 2.5 mm and 50% stenosis by visual estimation\n\nExclusion Criteria:\n\n* Cardiogenic shock at initial presentation or after infarct-related artery (IRA) treatment\n* Thrombolysis in myocardial infarction flow at non-IRA ≤ 2\n* Severe procedural complications during primary percutaneous coronary intervention that, in the judgement of the operator, preclude study enrollment\n* Non-IRA lesion unsuitable for percutaneous coronary intervention (PCI) treatment that, in the judgement of the operator, preclude study enrollment\n* Chronic total occlusion in a non-IRA\n* History of anaphylaxis to contrast agent\n* Pregnancy and lactation\n* Life expectancy \\\u003C 1 year\n* Severe valvular heart disease\n* History of coronary artery bypass grafting (CABG) or planned CABG\n* Fibrinolysis therapy prior to admission\n* Severe asthma","ALL","19 Years",{"count":256,"type":257},1252,"ESTIMATED","INTERVENTIONAL",[260],"NA","This prospective, multicenter, open-label, superiority trial will enroll patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease. Following successful percutaneous coronary intervention (PCI) of the infarct-related artery (IRA), patients who meet the eligibility criteria will be randomized in a 1:1 ratio to either in-hospital staged complete revascularization with PCI of non-IRA lesions performed on a separate day during hospitalization, at least 48 hours after PCI of the IRA, or out-of-hospital staged complete revascularization with PCI of non-IRA lesions performed after discharge between 15 and 45 days of randomization. In both groups, non-IRA lesions with 50-69% stenosis will be evaluated using FFR.",[263],"Myocardial Infarction (MI)",[265,266,267,268],"ST-segment myocardial infarction","Multivessel coronary artery disease","Complete revascularization","Timing","NOT_YET_RECRUITING","2026-08-13",{"date":272,"type":273},"2026-08-17","ACTUAL",{"date":275,"type":257},"2026-09-01",{"date":277,"type":257},"2035-07-31",{"name":5,"class":6},30]