[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100483305":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":29,"locations":34,"responsibleParty":86,"collaborators":88,"id":92,"slug":93,"hasResults":94,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":29,"eligibilityCriteria":98,"healthyVolunteers":99,"sex":100,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":29,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":29,"overallStatus":51,"whyStopped":29,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"University of Illinois at Chicago","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Clear Aligners with Dental Monitoring","EXPERIMENTAL","Experiment group: DM (Remote Dental Monitoring approach). Remote Dental Monitoring by DMTM will be implemented in the patient's orthodontic treatment. Pretreatment, 3D digital intra-oral scans will be uploaded to the DMTM dashboard, so they serve as the baseline for 3D tracking of tooth movement. Patients will be trained on how to use the DMTM application and do DM remote scans using their smartphones DM scan box and rector.\n\nThey will be instructed to do the DM scan after the initial tray insertion. Replacement of the aligners trays will be based on DM GO tracking function, which is specifically targeted at clear aligner treatment.",[13],"Device: Clear Aligners with Dental Monitoring",{"label":15,"type":16,"description":17,"interventionNames":18},"Clear Aligners replaced every 7 days","ACTIVE_COMPARATOR","Group 2:Control group. All subjects will have conventional aligner treatment with aligners replaced every 7 days, and standard in-office visits every 8 weeks.",[19],"Device: Clear Aligners",{"label":21,"type":16,"description":22,"interventionNames":23},"Clear Aligners replaced every 14 days","Group 3: (n=40) Control group. All subjects will have conventional aligner treatment with aligners replaced every 14 days, and standard in-office visits every 8 weeks.",[19],[25,30],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","Dental Monitoring™ (DM ™). This digital technology software allows orthodontists to monitor patients remotely through continuous analytics using control vision technology, metaheuristics, and artificial intelligence.31 This app utilizes a patented artificial intelligence machine learning algorithm to calculate 3-dimensional (3D) tooth movements from intraoral photos and videos that patients capture using their smartphone cameras.",[9],null,{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Clear Aligners","Removabale orthodontics appliances",[21,15],[35,49,68,77],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":29},"Orthodontic Specialists of Lake County (Antioch)","SUSPENDED","Antioch","Illinois","60002","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-88.09564,42.47724,{"lat":47,"lon":46},{"facility":50,"status":51,"city":52,"state":39,"zip":53,"country":41,"countryCode":42,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Department of Orthodontics, College of Dentistry University of Illinois Chicago","RECRUITING","Chicago","60612-7211",{"type":44,"coordinates":55},[56,57],-87.65005,41.85003,{"lat":57,"lon":56},[60,65],{"name":61,"role":62,"phone":63,"phoneExt":29,"email":64},"Mohammed Elnagar, DDS, MS.PhD","CONTACT","312-996-7505","melnagar@uic.edu",{"name":66,"role":62,"phone":63,"phoneExt":29,"email":67},"Lia Tahir, DDS","atahir3@uic.edu",{"facility":69,"status":37,"city":70,"state":39,"zip":71,"country":41,"countryCode":42,"cosmosGeoPoint":72,"geoPoint":76,"contacts":29},"Orthodontic Specialists of Lake County (Grayslake)","Grayslake","60030",{"type":44,"coordinates":73},[74,75],-88.04175,42.34447,{"lat":75,"lon":74},{"facility":78,"status":37,"city":79,"state":39,"zip":80,"country":41,"countryCode":42,"cosmosGeoPoint":81,"geoPoint":85,"contacts":29},"Orthodontic Specialists of Lake County (Gurnee)","Gurnee","60031",{"type":44,"coordinates":82},[83,84],-87.90202,42.3703,{"lat":84,"lon":83},{"type":87,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR",[89],{"name":90,"class":91},"American Association of Orthodontists Foundation","UNKNOWN","100483305","optimizing-orthodontic-appliances-efficiency-with-remote-dental-monitoring-and-artificial-intelligence-algorithms-100483305",false,"NCT05573308","Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms","Optimizing Clear Aligners Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms","Inclusion Criteria:\n\n* Patients who request clear aligner treatment with the sole aim of correcting dental alignment.\n* Patients must be 12 years old or older.\n* Complete permanent dentition (excluding third molars).\n* Non-extraction treatment,\n* Upper or lower labial segment crowding. malocclusion to be treated with more than 20 Clear Aligners.\n\nExclusion Criteria:\n\n* Patients with systematic diseases or syndromes\n* Patients with a history or current use of Bisphosphonates\n* Patients with current use of nonsteroidal anti-inflammatory drugs (NSAIDs)\n* Active periodontal disease\n* Presence of dental prostheses,\n* The presence of dental anomalies (7) The treatment combined with fixed appliances or other auxiliary appliances.",true,"ALL","12 Years","70 Years",{"count":104,"type":105},12,"ESTIMATED","INTERVENTIONAL",[108],"NA","The decision on aligner changing is based on orthodontists' personal experience and common knowledge that an approximated time span for the aligner have exhausted its biological efficacy. However, a one size fits all approach is not always ideal, as an average determined time is not taken into account of a patient's individual biological response. The aligners could be progressed earlier than the determined time, or they may stay inactive for a while, waiting for the in-office visit. Dental MonitoringTM is the only available technology that provides 3D monitoring of teeth movement, reconstructs 3D digital models remotely, and auto-detect clinical situations by their patented AI algorithms. The investigators have reported high accuracy of DMTM to monitor the tooth movement in vitro. However, the efficacy of DMTM on orthodontic treatment and the accuracy of DMTM in the orthodontic patients has not been investigated yet. In this proposal, the investigators are implementing the Dental MonitoringTM application and 3D tracking of tooth movement powered by AI algorisms as a novel tool to customize aligner changing intervals. The ultimate goal is to reduce in-office visits and treatment duration while maintaining regular monitoring, thus not jeopardizing expected results. It is imperative to investigate the Teledentistry for its effectiveness, reliability, ease of use, patient satisfaction, and value on the overall health and oral health system, especially as a critical tool during public health emergency situations.",[111,112],"Malocclusion","Misaligned Teeth","2026-07-06",{"date":115,"type":116},"2026-07-08","ACTUAL",{"date":118,"type":116},"2022-10-17",{"date":120,"type":105},"2029-12-30",{"name":5,"class":6},4]