[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646649":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":29,"responsibleParty":41,"collaborators":19,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":19,"enrollmentInfo":54,"targetDuration":19,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":19,"overallStatus":63,"whyStopped":19,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"University Hospital, Rouen","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Study Participants","EXPERIMENTAL","Collection of saliva and stool samples for microbiota analysis and assessment of handgrip strength in adults aged over 70 years.",[13],"Procedure: Salivary and fecal microbiota sampling and muscle strength assessment",[15],{"type":16,"name":17,"description":11,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Salivary and fecal microbiota sampling and muscle strength assessment",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Prof. DECHELOTTE","CONTACT","+33 2 32 88 56 70","pierre.dechelotte@chu-rouen.fr",{"name":27,"role":23,"phone":19,"phoneExt":19,"email":28},"HERVET","mylene.hervet@chu-rouen.fr",[30],{"facility":31,"status":19,"city":32,"state":19,"zip":19,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":19},"Rouen University Hospital","Rouen","France","FR",{"type":36,"coordinates":37},"Point",[38,39],1.09932,49.44313,{"lat":39,"lon":38},{"type":42,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100646649","oral-microbiota-and-muscle-function-in-the-ageing-subject-100646649",false,"NCT07687511","Oral Microbiota and Muscle Function in the Ageing Subject","Oral Microbiota and Muscle Function in the Ageing Subject: MYOBIOTA Study","MYOBIOTA","Inclusion Criteria:\n\n* Male or female adult volunteer, over 70 years of age\n* Non-hospitalised\n* Having read and understood the information letter and signed the consent form\n* Affiliated with a Social Security scheme\n\nExclusion Criteria:\n\n* Already included in an interventional drug clinical trial\n* Unable to understand and complete the questionnaires\n* Deprived of liberty by an administrative or judicial decision or protected adult subject (under guardianship, curatorship or judicial protection order)\n* Receiving antibiotic treatment or having received antibiotic treatment during the previous 3 months\n* Taking or having taken probiotics during the previous 3 months\n* Having undergone colonic lavage\u002Fbowel cleansing during the previous 3 months\n* Presenting one of the following situations likely to alter the microbiota: active cancer, eating disorders, exclusive vegetarian diet, history of digestive surgery\n* Having a cardiac pacemaker\n* Living in a nursing home for dependent elderly persons (EHPAD)",true,"ALL","70 Years",{"count":55,"type":56},60,"ESTIMATED","INTERVENTIONAL",[59],"NA","Ageing of the general population may be a risk factor for various complications, including sarcopenia. Sarcopenia is a progressive loss of muscle mass and muscle strength, leading to a decrease in functional capacities. It affects between 0.7% and 16% of European adults over 70 years of age (1). Recent studies suggest that the faecal microbiota may be altered with ageing but also according to sarcopenic status. Furthermore, no study has currently published data on the relationship between salivary microbiota and sarcopenic status. The main hypothesis of this study is that a decrease in salivary microbiota richness could be associated with impaired handgrip strength in the ageing subject.",[62],"Non-hospitalised Men and Women Over 70 Years of Age","NOT_YET_RECRUITING","2026-07-01",{"date":66,"type":67},"2026-07-07","ACTUAL",{"date":69,"type":56},"2026-07",{"date":71,"type":56},"2028-07",{"name":5,"class":6},1]