[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659412":3},{"organization":4,"outcomesModule":7,"designInfo":24,"detailedDescription":23,"studyPopulation":27,"armGroups":28,"interventions":39,"overallOfficials":23,"centralContacts":23,"locations":50,"responsibleParty":72,"collaborators":23,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":23,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":23,"studyType":87,"phases":23,"briefSummary":88,"conditions":89,"keywords":23,"overallStatus":92,"whyStopped":23,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Olistic Research Labs S.L.","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":23},[9],{"measure":10,"description":11,"timeFrame":12},"Triple and Bigger Follicular Units","Change in triple and bigger follicular units analyzed via phototrichoscopy.","6 months",[14,17,20],{"measure":15,"description":16,"timeFrame":12},"Single and Double Follicular Units","Change in single and double follicular units analyzed via phototrichoscopy.",{"measure":18,"description":19,"timeFrame":12},"Average Hair Thickness","Change in hair shaft diameter analyzed via phototrichoscopy.",{"measure":21,"description":22,"timeFrame":12},"Health-Related Quality of Life Questionnaire (HRQoL)","A HRQoL questionnaire (Hair-Specific Skindex-29 \u002F HSS-29) was used to assess three different spheres: emotions, functionality and symptoms.",null,{"allocation":23,"interventionModel":23,"interventionModelDescription":23,"primaryPurpose":23,"observationalModel":25,"timePerspective":26,"maskingInfo":23},"COHORT","RETROSPECTIVE","Adult women with a clinical diagnosis of female pattern hair loss (Ludwig or Olsen grade I) seen at the hair disorders unit of Instituto Médico Ricart, a dermatology clinic in Madrid, Spain.\n\nThe cohort includes patients treated with low-dose oral minoxidil, alone or combined with a multifactorial drinkable nutraceutical, as part of routine clinical practice. To be included, patients had to have a baseline and a 6-month assessment with standardized phototrichoscopy.",[29,34],{"label":30,"type":23,"description":31,"interventionNames":32},"Oral Minoxidil Monotherapy Arm","Patients who were prescribed with low-dose oral minoxidil as monotherapy.",[33],"Drug: Oral low-dose Minoxidil",{"label":35,"type":23,"description":36,"interventionNames":37},"Oral Minoxidil + Nutraceutical Arm","Patients who were prescribed with low-dose oral minoxidil + nutraceutical",[33,38],"Dietary Supplement: Drinkable multifactorial food supplement containing vitamins, minerals, plant extracts, and other bioactive compounds, formulated to support hair growth and scalp health in women.",[40,45],{"type":41,"name":42,"description":43,"armGroupLabels":44,"otherNames":23},"DRUG","Oral low-dose Minoxidil","Oral low-dose Minoxidil (0,5 - 1 mg)",[35,30],{"type":46,"name":47,"description":48,"armGroupLabels":49,"otherNames":23},"DIETARY_SUPPLEMENT","Drinkable multifactorial food supplement containing vitamins, minerals, plant extracts, and other bioactive compounds, formulated to support hair growth and scalp health in women.","Drinkable multifactorial food supplement in liquid form, administered once daily in a 25 mL single-dose vial, for a duration of 180 days. The formulation contains a combination of vitamins, minerals, plant extracts, amino acids, and other bioactive compounds designed to support hair growth and scalp health in women.",[35],[51],{"facility":52,"status":23,"city":53,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Clínica dermatológica IMR Madrid - Castellana","Madrid","28046","Spain","ES",{"type":58,"coordinates":59},"Point",[60,61],-3.70256,40.4165,{"lat":61,"lon":60},[64,69],{"name":65,"role":66,"phone":67,"phoneExt":23,"email":68},"Alba Gómez-Zubiaur","CONTACT","034910603150","a.gomez@imricart.com",{"name":70,"role":71,"phone":23,"phoneExt":23,"email":23},"Alba Gómez-Zubiaur, M.D., Ph.D.","PRINCIPAL_INVESTIGATOR",{"type":73,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100659412","oral-minoxidil-with-or-without-a-multifactorial-drinkable-nutraceutical-in-female-pattern-hair-loss-a-retrospective-study-100659412",false,"NCT07862374","Oral Minoxidil With or Without a Multifactorial Drinkable Nutraceutical in Female Pattern Hair Loss: a Retrospective Study","Efficacy of a Multifactorial Drinkable Nutraceutical Combined With Oral Minoxidil Versus Oral Minoxidil Monotherapy in FPHL: A 6-Month Retrospective Observational Study","Inclusion Criteria:\n\n* Women aged 20-50 years.\n* Dermatologist-confirmed diagnosis (based on clinical and trichoscopic examination) of mild female androgenetic alopecia (FAGA) (Ludwig grade I or Olsen grade I), treated for at least 6 months with low-dose oral minoxidil (0.5-1 mg), either as monotherapy or in combination with Olistic® Women, between October 2023 and June 2026.\n* Availability of TrichoScan imaging at baseline and after 6 months of treatment, together with a hair-shedding record after washing provided at the clinic visit and a questionnaire assessing psychological impact.\n\nExclusion Criteria:\n\n* FAGA of a higher grade.\n* Missing imaging, psychological questionnaire or hair-shedding collection at baseline or at 6 months.\n* Concomitant treatment with any other drug (oral, topical or by mesotherapy) or any other food supplement during the 6-month study period.\n* Treatment with FAGA-specific drugs (by any route of administration) within the 6 months prior to study inclusion.\n* Substantial change in hair colour, hairstyle, or a marked haircut during the 6-month study period.\n* Refusal to participate in the study.","FEMALE","20 Years","50 Years",{"count":85,"type":86},30,"ESTIMATED","OBSERVATIONAL","This retrospective observational study evaluates the outcomes of a multifactorial drinkable nutraceutical combined with oral minoxidil, compared with oral minoxidil monotherapy, in women with female pattern hair loss (FPHL) treated in routine clinical practice.\n\nData were collected from a cohort of women with FPHL (Ludwig or Olsen grade I) who received either oral minoxidil alone or oral minoxidil plus the nutraceutical for 6 months. Outcomes were assessed at baseline and at 6 months. The main assessment was standardized phototrichoscopy in the frontal region. Patient-reported outcomes included a hair-specific adaptation of the Skindex-29 quality-of-life questionnaire and a treatment perception questionnaire. Adverse events were also recorded.\n\nThe study aims to explore whether adding the nutraceutical to oral minoxidil gives additional benefits in hair density, hair thickness and quality of life compared with oral minoxidil alone.",[90,91],"Female Pattern Hair Loss","Female Pattern Hair Loss, Androgenic Alopecia","NOT_YET_RECRUITING","2026-10-01",{"date":95,"type":96},"2026-10-07","ACTUAL",{"date":98,"type":86},"2026-10",{"date":100,"type":86},"2027-02",{"name":5,"class":6},1]